{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T09:01:02Z","timestamp":1773478862587,"version":"3.50.1"},"reference-count":222,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2022,9,24]],"date-time":"2022-09-24T00:00:00Z","timestamp":1663977600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>The influence of pharmacotherapy regimens on surgical patient outcomes is increasingly appreciated in the era of enhanced recovery protocols and institutional focus on reducing postoperative complications. Specifics related to medication selection, dosing, frequency of administration, and duration of therapy are evolving to optimize pharmacotherapeutic regimens for many enhanced recovery protocolized elements. This review provides a summary of recent pharmacotherapeutic strategies, including those configured within electronic health record (EHR) applications and functionalities, that are associated with the minimization of the frequency and severity of postoperative complications (POCs), shortened hospital length of stay (LOS), reduced readmission rates, and cost or revenue impacts. Further, it will highlight preventive pharmacotherapy regimens that are correlated with improved patient preparation, especially those related to surgical site infection (SSI), venous thromboembolism (VTE), nausea and vomiting (PONV), postoperative ileus (POI), and emergence delirium (PoD) as well as less commonly encountered POCs such as acute kidney injury (AKI) and atrial fibrillation (AF). The importance of interprofessional collaboration in all periprocedural phases, focusing on medication management through shared responsibilities for drug therapy outcomes, will be emphasized. Finally, examples of collaborative care through shared mental models of drug stewardship and non-medical practice agreements to improve operative throughput, reduce operative stress, and increase patient satisfaction are illustrated.<\/jats:p>","DOI":"10.3390\/jcm11195628","type":"journal-article","created":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T01:41:58Z","timestamp":1664156518000},"page":"5628","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Positive Patient Postoperative Outcomes with Pharmacotherapy: A Narrative Review including Perioperative-Specialty Pharmacist Interviews"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5324-9139","authenticated-orcid":false,"suffix":"II","given":"Richard H.","family":"Parrish","sequence":"first","affiliation":[{"name":"Department of Biomedical Sciences, Mercer University School of Medicine, Columbus, GA 31902, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heather Monk","family":"Bodenstab","sequence":"additional","affiliation":[{"name":"Department of Medical Science, Sobi Pharma, Waltham, MA 02451, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dustin","family":"Carneal","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Services, Crystal Clinic Orthopedic Center, Akron, OH 44312, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan M.","family":"Cassity","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Services, Mayo Clinic\u2013Rochester, Rochester, MN 55905, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William E.","family":"Dager","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Services, University of California Davis, Sacramento, CA 95817, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2572-629X","authenticated-orcid":false,"given":"Sara J.","family":"Hyland","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Services, OhioHealth\/Grant Medical Center, Columbus, OH 43215, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jenna K.","family":"Lovely","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Services, Mayo Clinic\u2013Rochester, Rochester, MN 55905, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9600-0520","authenticated-orcid":false,"given":"Alyssa","family":"Pollock","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Practice, Creighton University School of Pharmacy and Health Professions, Omaha, NE 68178, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tracy M.","family":"Sparkes","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, University of Maryland Medical Center, Baltimore, MD 21201, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siu-Fun","family":"Wong","sequence":"additional","affiliation":[{"name":"Division of Hematology\/Oncology, Department of Medicine, UCI Health, Orange, CA 92868, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e54","DOI":"10.1111\/anae.14860","article-title":"Enhanced postoperative recovery: Good from afar, but far from good?","volume":"75","author":"Kehlet","year":"2020","journal-title":"Anaesthesia"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1001\/jamasurg.2016.4952","article-title":"Enhanced Recovery After Surgery: A Review","volume":"152","author":"Ljungqvist","year":"2017","journal-title":"JAMA Surg."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.ijsu.2019.01.006","article-title":"Clinical pharmacist perspectives for optimizing pharmacotherapy within Enhanced Recovery After Surgery (ERAS\u00ae) programs","volume":"63","author":"Lovely","year":"2019","journal-title":"Int. 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