{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T18:41:52Z","timestamp":1791830512778,"version":"4.3.4"},"reference-count":83,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T00:00:00Z","timestamp":1664150400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Patients with single-sided deafness can experience an ipsilateral disabling tinnitus that has a major impact on individuals\u2019 social communication and quality of life. Cochlear implants appear to be superior to conventional treatments to alleviate tinnitus in single-sided deafness. We conducted a systematic review to evaluate the effectiveness of cochlear implants in single-sided deafness with disabling tinnitus when conventional treatments fail to alleviate tinnitus (PROSPERO ID: CRD42022353292). All published studies in PubMed\/MEDLINE and SCOPUS databases until December 2021 were included. A total of 474 records were retrieved, 31 studies were included and were divided into two categories according to whether tinnitus was assessed as a primary complaint or not. In all studies, cochlear implantation, evaluated using subjective validated tools, succeeded in reducing tinnitus significantly. Objective evaluation tools were less likely to be used but showed similar results. A short-(3 months) and long-(up to 72 months) term tinnitus suppression was reported. When the cochlear implant is disactivated, complete residual tinnitus inhibition was reported to persist up to 24 h. The results followed a similar pattern in studies where tinnitus was assesed as a primary complaint or not. In conclusion, the present review confirmed the effectiveness of cochlear implantation in sustainably reducing disabling tinnitus in single-sided deafness patients.<\/jats:p>","DOI":"10.3390\/jcm11195664","type":"journal-article","created":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T01:51:49Z","timestamp":1664329909000},"page":"5664","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Short- and Long-Term Effect of Cochlear Implantation on Disabling Tinnitus in Single-Sided Deafness Patients: A Systematic Review"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7782-0005","authenticated-orcid":false,"given":"Samar A.","family":"Idriss","sequence":"first","affiliation":[{"name":"Department of Audiology and Otoneurological Evaluation, Edouard Herriot Hospital, Hospices Civils de Lyon, 69002 Lyon, France"},{"name":"Department of Otorhinolaryngology and Head and Neck Surgery, Eye and Ear University Hospital, Holy Spirit University of Kaslik, Beirut 1202, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5901-4392","authenticated-orcid":false,"given":"Pierre","family":"Reynard","sequence":"additional","affiliation":[{"name":"Department of Audiology and Otoneurological Evaluation, Edouard Herriot Hospital, Hospices Civils de Lyon, 69002 Lyon, France"},{"name":"Institut de l\u2019Audition, Institut Pasteur, University of Paris, INSERM, 75012 Paris, France"},{"name":"Faculty of Medicine, University Claude Bernard Lyon 1, 69100 Villeurbanne, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathieu","family":"Marx","sequence":"additional","affiliation":[{"name":"Department of Otology, Otoneurology and Pediatric Otolaryngology, Pierre-Paul Riquet Hospital, Toulouse Purpan University Hospital, 31300 Toulouse, France"},{"name":"Brain and Cognition Laboratory, UMR 5549, Toulouse III University, 31062 Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albane","family":"Mainguy","sequence":"additional","affiliation":[{"name":"National Commission for the Evaluation of Medical Devices and Health Technologies, Haute Autorit\u00e9 de Sant\u00e9, 93210 La Plaine St Denis, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles-Alexandre","family":"Joly","sequence":"additional","affiliation":[{"name":"Department of Audiology and Otoneurological Evaluation, Edouard Herriot Hospital, Hospices Civils de Lyon, 69002 Lyon, France"},{"name":"Institut de l\u2019Audition, Institut Pasteur, University of Paris, INSERM, 75012 Paris, France"},{"name":"Faculty of Medicine, University Claude Bernard Lyon 1, 69100 Villeurbanne, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugen Constant","family":"Ionescu","sequence":"additional","affiliation":[{"name":"Department of Audiology and Otoneurological Evaluation, Edouard Herriot Hospital, Hospices Civils de Lyon, 69002 Lyon, France"},{"name":"Institut de l\u2019Audition, Institut Pasteur, University of Paris, INSERM, 75012 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2667-9499","authenticated-orcid":false,"given":"Kelly K. S.","family":"Assouly","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Head & Neck Surgery, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands"},{"name":"UMC Utrecht Brain Center, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands"},{"name":"Cochlear Technology Centre, 2800 Mechelen, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hung","family":"Thai-Van","sequence":"additional","affiliation":[{"name":"Department of Audiology and Otoneurological Evaluation, Edouard Herriot Hospital, Hospices Civils de Lyon, 69002 Lyon, France"},{"name":"Institut de l\u2019Audition, Institut Pasteur, University of Paris, INSERM, 75012 Paris, France"},{"name":"Faculty of Medicine, University Claude Bernard Lyon 1, 69100 Villeurbanne, France"},{"name":"National Commission for the Evaluation of Medical Devices and Health Technologies, Haute Autorit\u00e9 de Sant\u00e9, 93210 La Plaine St Denis, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Snapp, H.A., and Ausili, S.A. 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