{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T18:25:44Z","timestamp":1777573544551,"version":"3.51.4"},"reference-count":58,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2022,9,30]],"date-time":"2022-09-30T00:00:00Z","timestamp":1664496000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Despite advances in treatment of anorexia nervosa (AN), current therapeutic approaches do not fully consider gastrointestinal disturbances (GID), often present in AN. Addressing GID, both symptoms and disorders, is likely to improve treatment adherence and outcomes in people with AN. GID are complex and are linked to a range of factors related to eating disorder symptomology and can be impacted by nutritional treatment. It is not known which dietetic practices are currently used to address GID in AN. Therefore, this survey aimed to explore the perceived knowledge, attitudes, and practices (KAP) of Australian dietitians treating AN and co-occurring GID. Seventy dietitians participated by completing an online survey. Knowledge scores were calculated based on correct responses to knowledge items (total: 12 points); and two groups were generated: higher knowledge (\u226510 points, n = 31) and lower knowledge (\u22649 points, n = 39). A greater proportion of dietitians with higher knowledge recognized the role of GID in pathogenesis of AN (p = 0.002) and its impact on quality of life (p = 0.013) and screened for GID (p \u2264 0.001), compared with those with lower knowledge. These results suggest that attitudes and practices toward patients presenting with AN and GID differ depending on level of knowledge. This may have important implications for treatment outcomes for individuals with AN and GID.<\/jats:p>","DOI":"10.3390\/jcm11195833","type":"journal-article","created":{"date-parts":[[2022,10,8]],"date-time":"2022-10-08T23:39:31Z","timestamp":1665272371000},"page":"5833","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Diet, Digestion, and the Dietitian: A Survey of Clinicians\u2019 Knowledge, Attitudes and Practices to Advance the Treatment of Gastrointestinal Disturbances in Individuals with Anorexia Nervosa"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6590-0486","authenticated-orcid":false,"given":"Madeline L.","family":"West","sequence":"first","affiliation":[{"name":"Food & Mood Centre, IMPACT\u2014The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Deakin University, Geelong 3220, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caitlin","family":"McMaster","sequence":"additional","affiliation":[{"name":"Children\u2019s Hospital Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Westmead 2145, Australia"},{"name":"Eating and Nutrition Research Group, School of Medicine, Western Sydney University, Campbelltown 2560, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire L.","family":"Young","sequence":"additional","affiliation":[{"name":"Food & Mood Centre, IMPACT\u2014The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Deakin University, Geelong 3220, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammadreza","family":"Mohebbi","sequence":"additional","affiliation":[{"name":"Faculty of Health, Biostatistics Unit, Deakin University, Geelong 3216, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Hart","sequence":"additional","affiliation":[{"name":"Eating and Nutrition Research Group, School of Medicine, Western Sydney University, Campbelltown 2560, Australia"},{"name":"Nutrition Services, St Vincent\u2019s Health Network, Darlinghurst 2010, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heidi M.","family":"Staudacher","sequence":"additional","affiliation":[{"name":"Food & Mood Centre, IMPACT\u2014The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Deakin University, Geelong 3220, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy","family":"Loughman","sequence":"additional","affiliation":[{"name":"Food & Mood Centre, IMPACT\u2014The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Deakin University, Geelong 3220, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anu","family":"Ruusunen","sequence":"additional","affiliation":[{"name":"Food & Mood Centre, IMPACT\u2014The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Deakin University, Geelong 3220, Australia"},{"name":"Institute of Public Health and Clinical Nutrition, University of Eastern Finland, 70211 Kuopio, Finland"},{"name":"Department of Psychiatry, Kuopio University Hospital, 70210 Kuopio, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetyana","family":"Rocks","sequence":"additional","affiliation":[{"name":"Food & Mood Centre, IMPACT\u2014The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Deakin University, Geelong 3220, Australia"},{"name":"Eating and Nutrition Research Group, School of Medicine, Western Sydney University, Campbelltown 2560, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1002\/eat.23527","article-title":"Evaluating disorders of gut-brain interaction in eating disorders","volume":"54","author":"Wiklund","year":"2021","journal-title":"Int. J. Eat. Disord."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1002\/erv.2679","article-title":"Gastrointestinal alterations in anorexia nervosa\u2014A systematic review","volume":"27","author":"Schalla","year":"2019","journal-title":"Eur. Eat. Disord. Rev."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1001\/archgenpsychiatry.2011.74","article-title":"Mortality rates in patients with anorexia nervosa and other eating disorders: A meta-analysis of 36 studies","volume":"68","author":"Arcelus","year":"2011","journal-title":"Arch. Gen. Psychiatry"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1053\/j.gastro.2016.02.032","article-title":"Functional Gastrointestinal Disorders: History, Pathophysiology, Clinical Features and Rome IV","volume":"150","author":"Drossman","year":"2016","journal-title":"Gastroenterology"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1037\/0033-2909.130.1.19","article-title":"Coming to terms with risk factors for eating disorders: Application of risk terminology and suggestions for a general taxonomy","volume":"130","author":"Jacobi","year":"2004","journal-title":"Psychol. Bull."},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Santonicola, A., Gagliardi, M., Guarino, M.P.L., Siniscalchi, M., Ciacci, C., and Iovino, P. (2019). Eating Disorders and Gastrointestinal Diseases. Nutrients, 11.","DOI":"10.3390\/nu11123038"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.autneu.2006.07.023","article-title":"Gastrointestinal disturbances in eating disorders: Clinical and neurobiological aspects","volume":"129","author":"Zipfel","year":"2006","journal-title":"Auton. Neurosci."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1002\/eat.23469","article-title":"Gastrointestinal symptoms following treatment for anorexia nervosa: A systematic literature review","volume":"54","author":"West","year":"2021","journal-title":"Int. J. Eat. Disord."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"195","DOI":"10.3389\/fpsyt.2020.00195","article-title":"Which Symptoms, Complaints and Complications of the Gastrointestinal Tract Occur in Patients with Eating Disorders? A Systematic Review and Quantitative Analysis","volume":"11","author":"Riedlinger","year":"2020","journal-title":"Front. Psychiatry"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1111\/j.1365-2982.2010.01576.x","article-title":"Appearance and disappearance of functional gastrointestinal disorders in patients with eating disorders","volume":"22","author":"Boyd","year":"2010","journal-title":"Neurogastroenterol. Motil."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1002\/eat.22070","article-title":"Increased emergency department use by adolescents and young adults with eating disorders","volume":"46","author":"Lipson","year":"2013","journal-title":"Int. J. Eat. Disord."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.jpsychores.2010.11.009","article-title":"Exploring eating disorder quality of life and functional gastrointestinal disorders among eating disorder patients","volume":"70","author":"Abraham","year":"2011","journal-title":"J. Psychosom. Res."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"12262","DOI":"10.1038\/s41598-021-90739-w","article-title":"Visual mapping of body image disturbance in anorexia nervosa reveals objective markers of illness severity","volume":"11","author":"Arevian","year":"2021","journal-title":"Sci. Rep."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1002\/cpp.760","article-title":"Fluctuations of body images in anorexia nervosa: Patients\u2019 perception of contextual triggers","volume":"19","author":"Espeset","year":"2012","journal-title":"Clin. Psychol. Psychother."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1002\/1098-108X(200103)29:2<224::AID-EAT1012>3.0.CO;2-R","article-title":"Rationales for food refusal in chinese patients with anorexia nervosa","volume":"29","author":"Lee","year":"2001","journal-title":"Int. J. Eat. Disord."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1111\/j.1365-2982.2010.01621.x","article-title":"Can eating disorders cause functional gastrointestinal disorders?","volume":"22","author":"Janssen","year":"2010","journal-title":"Neurogastroenterol. Motil."},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Blanchet, C., Guillaume, S., Bat-Pitault, F., Carles, M.E., Clarke, J., Dodin, V., Duriez, P., Gerardin, P., Hanachi-Guidoum, M., and Iceta, S. (2019). Medication in AN: A Multidisciplinary Overview of Meta-Analyses and Systematic Reviews. J. Clin. Med., 8.","DOI":"10.3390\/jcm8020278"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1002\/eat.23555","article-title":"Brain-gut psychotherapies: Promising tools to address gastrointestinal problems in patients with eating disorders","volume":"54","author":"Wildes","year":"2021","journal-title":"Int. J. Eat. Disord."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1002\/eat.23255","article-title":"On bells, saliva, and abdominal pain or discomfort: Early aversive visceral conditioning and vulnerability for anorexia nervosa","volume":"53","author":"Zucker","year":"2020","journal-title":"Int. J. Eat. Disord."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1177\/0004867414555814","article-title":"Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for the treatment of eating disorders","volume":"48","author":"Hay","year":"2014","journal-title":"Aust. N. Z. J. Psychiatry"},{"key":"ref_21","unstructured":"Dietitians Australia (2018). Gastroenterology Role Statement, Dietitians Australia."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.jpsychores.2004.04.375","article-title":"Eating disorders and irritable bowel syndrome: Is there a link?","volume":"59","author":"Perkins","year":"2005","journal-title":"J. Psychosom. Res."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1136\/gutjnl-2017-313750","article-title":"The low FODMAP diet: Recent advances in understanding its mechanisms and efficacy in IBS","volume":"66","author":"Staudacher","year":"2017","journal-title":"Gut"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.cgh.2019.08.018","article-title":"From a Dietitian\u2019s Perspective, Diets for Irritable Bowel Syndrome Are Not One Size Fits All","volume":"18","author":"Scarlata","year":"2020","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"ref_25","first-page":"439","article-title":"Defecatory disorders in anorexia nervosa: A clinical study","volume":"18","author":"Sileri","year":"2014","journal-title":"Tech. Coloproctol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.dld.2013.02.022","article-title":"Audit of digestive complaints and psychopathological traits in patients with eating disorders: A prospective study","volume":"45","author":"Salvioli","year":"2013","journal-title":"Dig. Liver Dis."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1097\/MCG.0b013e31820fb914","article-title":"World gastroenterology rganization global guideline: Constipation\u2014A global perspective","volume":"45","author":"Lindberg","year":"2011","journal-title":"J. Clin. Gastroenterol."},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Heruc, G.A., Little, T.J., Kohn, M., Madden, S., Clarke, S., Horowitz, M., and Feinle-Bisset, C. (2018). Appetite Perceptions, Gastrointestinal Symptoms, Ghrelin, Peptide YY and State Anxiety Are Disturbed in Adolescent Females with Anorexia Nervosa and Only Partially Restored with Short-Term Refeeding. Nutrients, 11.","DOI":"10.3390\/nu11010059"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1002\/eat.23471","article-title":"Validating the visceral sensitivity index in an eating disorder sample","volume":"54","author":"Brown","year":"2021","journal-title":"Int. J. Eat. Disord."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1177\/0253717620946111","article-title":"Designing and Conducting Knowledge, Attitude, and Practice Surveys in Psychiatry: Practical Guidance","volume":"42","author":"Andrade","year":"2020","journal-title":"Indian J. Psychol. Med."},{"key":"ref_31","first-page":"7","article-title":"Guideline for Conducting a Knowledge, Attitude ad Practice (KAP) Study","volume":"IV","author":"Kaliyaperumal","year":"2004","journal-title":"AECS Illum."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.jada.2005.12.005","article-title":"Perceived knowledge, attitudes, and practices of California registered dietitians regarding dietary supplements","volume":"106","author":"Hetherwick","year":"2006","journal-title":"J. Am. Diet. Assoc."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1111\/1747-0080.12519","article-title":"Australian dietitians\u2019 beliefs and attitudes towards weight loss counselling and health at every size counselling for larger-bodied clients","volume":"76","author":"Willer","year":"2019","journal-title":"Nutr. Diet."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1111\/jpc.14342","article-title":"Functional gastrointestinal disorders in children and adolescents: Knowledge, practice and attitudes of Australian paediatricians","volume":"55","author":"Heinsch","year":"2019","journal-title":"J. Paediatr. Child Health"},{"key":"ref_35","first-page":"29","article-title":"Knowledge and Attitudes of Gastroenterologists towards Eating Disorders","volume":"2","author":"Riaz","year":"2017","journal-title":"ARC J. Psychiatry"},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Rodrigues, I.B., Adachi, J.D., Beattie, K.A., and MacDermid, J.C. (2017). Development and validation of a new tool to measure the facilitators, barriers and preferences to exercise in people with osteoporosis. BMC Musculoskelet. Disord., 18.","DOI":"10.1186\/s12891-017-1914-5"},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Cohen, J. (2013). Statistical Power Analysis for the Behavioral Sciences, Routledge.","DOI":"10.4324\/9780203771587"},{"key":"ref_38","unstructured":"StataCorp (Stata Statistical Software: Release 17, 2021). Stata Statistical Software: Release 17."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"e480","DOI":"10.7861\/clinmed.2021-0189","article-title":"Functional gastrointestinal disorders: History taking skills in practice","volume":"21","author":"Daly","year":"2021","journal-title":"Clin. Med."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.apnu.2016.09.002","article-title":"Knowledge, Attitudes and Challenges of Healthcare Professionals Managing People with Eating Disorders: A Literature Review","volume":"31","author":"Seah","year":"2017","journal-title":"Arch. Psychiatr. Nurs."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1002\/erv.666","article-title":"Discursive constructions of \u2018eating disorders nursing\u2019: An analysis of nurses\u2019 accounts of nursing eating disorder patients","volume":"14","author":"Ryan","year":"2006","journal-title":"Eur. Eat. Disord. Rev."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40337-018-0231-1","article-title":"Physicians\u2019 perspectives on the treatment of patients with eating disorders in the acute setting","volume":"7","author":"Davidson","year":"2019","journal-title":"J. Eat. Disord."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"383","DOI":"10.12968\/ijtr.2011.18.7.383","article-title":"Barriers and attitudes health professionals working in eating disorders experience","volume":"18","author":"Walker","year":"2011","journal-title":"Int. J. Ther. Rehabil."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1080\/10640266.2012.668476","article-title":"A qualitative analysis of job burnout in eating disorder treatment providers","volume":"20","author":"Warren","year":"2012","journal-title":"Eat. Disord."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1016\/j.cgh.2019.12.007","article-title":"Improving Patient-Provider Relationships to Improve Health Care","volume":"18","author":"Drossman","year":"2020","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.1016\/S0140-6736(20)32115-2","article-title":"Functional gastrointestinal disorders: Advances in understanding and management","volume":"396","author":"Black","year":"2020","journal-title":"Lancet"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"e14188","DOI":"10.1111\/nmo.14188","article-title":"Narrative review: Risk of eating disorders and nutritional deficiencies with dietary therapies for irritable bowel syndrome","volume":"34","author":"Simons","year":"2021","journal-title":"Neurogastroenterol. Motil."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s11920-022-01318-3","article-title":"Gastrointestinal Interoception in Eating Disorders: Charting a New Path","volume":"24","author":"Khalsa","year":"2022","journal-title":"Curr. Psychiatry Rep."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1037\/a0022186","article-title":"Alliance in individual psychotherapy","volume":"48","author":"Horvath","year":"2011","journal-title":"Psychotherapy"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1186\/s40337-020-00334-z","article-title":"ANZAED practice and training standards for dietitians providing eating disorder treatment","volume":"8","author":"Heruc","year":"2020","journal-title":"J. Eat. Disord."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1016\/j.jand.2021.12.006","article-title":"Discrepancies Between Australian Eating Disorder Clinicians and Consumers Regarding Essential Components of Dietetic Treatment","volume":"122","author":"McMaster","year":"2021","journal-title":"J. Acad. Nutr. Diet."},{"key":"ref_52","doi-asserted-by":"crossref","unstructured":"Resmark, G., Herpertz, S., Herpertz-Dahlmann, B., and Zeeck, A. (2019). Treatment of Anorexia Nervosa-New Evidence-Based Guidelines. J. Clin. Med., 8.","DOI":"10.3390\/jcm8020153"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1111\/jhn.12756","article-title":"A model of the multidimensional nature of experienced dietitian clinical decision-making in the acute care setting","volume":"33","author":"Vo","year":"2020","journal-title":"J. Hum. Nutr. Diet."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1002\/eat.20636","article-title":"Primary care physicians\u2019 knowledge of and attitudes toward the eating disorders: Do they affect clinical actions?","volume":"42","author":"Currin","year":"2009","journal-title":"Int. J. Eat. Disord."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/s40337-021-00380-1","article-title":"Understanding training needs in eating disorders of graduating and new graduate dietitians in Australia: An online survey","volume":"9","author":"Denman","year":"2021","journal-title":"J. Eat. Disord."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1097\/TIN.0000000000000059","article-title":"Education and Practice Gaps of Registered Dietitian Nutritionists Working with Clients with Eating Disorders","volume":"31","author":"Trammell","year":"2016","journal-title":"Top. Clin. Nutr."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1002\/eat.23553","article-title":"The intersect of gastrointestinal symptoms and malnutrition associated with anorexia nervosa and avoidant\/restrictive food intake disorder: Functional or pathophysiologic?-A systematic review","volume":"54","author":"Gibson","year":"2021","journal-title":"Int. J. Eat. Disord."},{"key":"ref_58","unstructured":"Health Workforce Australia (2014). Australia\u2019s Health Workforce Series\u2014Dietitians in Focus, Health Workforce Australia."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/11\/19\/5833\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:44:54Z","timestamp":1760143494000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/11\/19\/5833"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,30]]},"references-count":58,"journal-issue":{"issue":"19","published-online":{"date-parts":[[2022,10]]}},"alternative-id":["jcm11195833"],"URL":"https:\/\/doi.org\/10.3390\/jcm11195833","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,30]]}}}