{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T03:04:50Z","timestamp":1765422290551,"version":"build-2065373602"},"reference-count":40,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2022,10,5]],"date-time":"2022-10-05T00:00:00Z","timestamp":1664928000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: LUS is a validated tool for the management of COVID-19 pneumonia. Chair positioning (CP) may have beneficial effects on oxygenation and lung aeration, and may be an easier alternative to PP. This study assessed the effects of a CP session on oxygenation and lung aeration (LA) changes in non-intubated COVID-19 patients. Methods: A retrospective multicenter study was conducted in an ICU. We analyzed data from LUS exams and SpO2:FiO2 performed before\/after a CP session in non-intubated COVID-19 patients. Patients were divided into groups of responders or non-responders in terms of oxygenation or LA. Results: Thirty-three patients were included in the study; fourteen (44%) were oxygenation non-responders and eighteen (56%) were oxygenation responders, while thirteen (40.6%) and nineteen (59.4%) patients were classified as LA non-responders and responders, respectively. Changes in oxygenation and LA before\/after a CP session were not correlated (r = \u22120.19, p = 0.3, 95% CI: \u22120.5\u20130.17). The reaeration scores did not differ between oxygenation responders and non-responders (1 (\u22120.75\u20133.75) vs. 4 (\u22121\u20136), p = 0.41). The LUS score was significantly correlated with SpO2:FiO2 before a CP session (r = 0.37, p = 0.04, 95% CI: 0.03\u20130.64) but not after (r = 0.17, p = 0.35, 95% CI: \u22120.19\u20130.50). Conclusion: A CP session was associated with improved oxygenation and LA in more than half of the non-intubated COVID-19 patients.<\/jats:p>","DOI":"10.3390\/jcm11195885","type":"journal-article","created":{"date-parts":[[2022,10,8]],"date-time":"2022-10-08T23:39:31Z","timestamp":1665272371000},"page":"5885","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Effects of a Chair Positioning Session on Awake Non-Intubated COVID-19 Pneumonia Patients: A Multicenter, Observational, and Pilot Study Using Lung Ultrasound"],"prefix":"10.3390","volume":"11","author":[{"given":"Alexandre","family":"Lopez","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Intensive Care, H\u00f4pital Nord, Assistance Publique H\u00f4pitaux de Marseille, Aix-Marseille University, 13015 Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0682-9405","authenticated-orcid":false,"given":"Pierre","family":"Simeone","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care Medicine, University Hospital Timone, AP-HM, Aix Marseille University, 13015 Marseille, France"},{"name":"CNRS, Inst Neurosci Timone, Aix Marseille University, UMR 7289, 13385 Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louis","family":"Delamarre","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care, H\u00f4pital Nord, Assistance Publique H\u00f4pitaux de Marseille, Aix-Marseille University, 13015 Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3305-0077","authenticated-orcid":false,"given":"Gary","family":"Duclos","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care, H\u00f4pital Nord, Assistance Publique H\u00f4pitaux de Marseille, Aix-Marseille University, 13015 Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte","family":"Arbelot","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care, H\u00f4pital Nord, Assistance Publique H\u00f4pitaux de Marseille, Aix-Marseille University, 13015 Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0049-6248","authenticated-orcid":false,"given":"Ines","family":"Lakbar","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care, H\u00f4pital Nord, Assistance Publique H\u00f4pitaux de Marseille, Aix-Marseille University, 13015 Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6836-3903","authenticated-orcid":false,"given":"Bruno","family":"Pastene","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care, H\u00f4pital Nord, Assistance Publique H\u00f4pitaux de Marseille, Aix-Marseille University, 13015 Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karine","family":"Bezulier","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care, H\u00f4pital Nord, Assistance Publique H\u00f4pitaux de Marseille, Aix-Marseille University, 13015 Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Dahan","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care, H\u00f4pital Nord, Assistance Publique H\u00f4pitaux de Marseille, Aix-Marseille University, 13015 Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9182-7286","authenticated-orcid":false,"given":"Emilie","family":"Joffredo","sequence":"additional","affiliation":[{"name":"Hospices Civils de Lyon, Centre Hospitalier Lyon-Sud, Service de R\u00e9animation, 69310 Pierre-B\u00e9nite, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucille","family":"Jay","sequence":"additional","affiliation":[{"name":"Hospices Civils de Lyon, Centre Hospitalier Lyon-Sud, Service de R\u00e9animation, 69310 Pierre-B\u00e9nite, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lionel","family":"Velly","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care Medicine, University Hospital Timone, AP-HM, Aix Marseille University, 13015 Marseille, France"},{"name":"CNRS, Inst Neurosci Timone, Aix Marseille University, UMR 7289, 13385 Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0988-1716","authenticated-orcid":false,"given":"Bernard","family":"Allaouchiche","sequence":"additional","affiliation":[{"name":"Hospices Civils de Lyon, Centre Hospitalier Lyon-Sud, Service de R\u00e9animation, 69310 Pierre-B\u00e9nite, France"},{"name":"Department of Anesthesiology and Critical Care Medicine, Facult\u00e9 de M\u00e9decine et de Ma\u00efeutique Lyon Sud-Charles M\u00e9rieux, Universit\u00e9 Claude Bernard Lyon 1, 69100 Villeurbanne, France"},{"name":"VetAgro Sup, Campus V\u00e9t\u00e9rinaire de Lyon, 69007 Marcy l\u2019\u00c9toile, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sami","family":"Hraiech","sequence":"additional","affiliation":[{"name":"Service de M\u00e9decine Intensive\u2014R\u00e9animation, AP-HM, H\u00f4pital Nord, 13015 Marseille, France"},{"name":"Health Service Research and Quality of Life Center (CEReSS), 27 Boulevard Jean-Moulin, Aix-Marseille Universit\u00e9, 13005 Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3097-758X","authenticated-orcid":false,"given":"Marc","family":"Leone","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care, H\u00f4pital Nord, Assistance Publique H\u00f4pitaux de Marseille, Aix-Marseille University, 13015 Marseille, France"},{"name":"Center for Cardiovascular and Nutrition Research (C2VN), Aix Marseille Universit\u00e9, INSERM, INRA, 13005 Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurent","family":"Zieleskiewicz","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care, H\u00f4pital Nord, Assistance Publique H\u00f4pitaux de Marseille, Aix-Marseille University, 13015 Marseille, France"},{"name":"Center for Cardiovascular and Nutrition Research (C2VN), Aix Marseille Universit\u00e9, INSERM, INRA, 13005 Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1007\/s00134-020-06186-0","article-title":"Comparative study of lung ultrasound and chest computed tomography scan in the assessment of severity of confirmed COVID-19 pneumonia","volume":"46","author":"Zieleskiewicz","year":"2020","journal-title":"Intensive Care Med."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1186\/s13054-020-03369-5","article-title":"Multi-organ point-of-care ultrasound for COVID-19 (PoCUS4COVID): International expert consensus","volume":"24","author":"Hussain","year":"2020","journal-title":"Crit. 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Med."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/S2213-2600(20)30268-X","article-title":"Feasibility and physiological effects of prone positioning in non-intubated patients with acute respiratory failure due to COVID-19 (PRON-COVID): A prospective cohort study","volume":"8","author":"Coppo","year":"2020","journal-title":"Lancet Respir. Med."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1136\/thoraxjnl-2020-215133","article-title":"Awake prone positioning in COVID-19","volume":"75","author":"Koeckerling","year":"2020","journal-title":"Thorax"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"R230","DOI":"10.1186\/cc10471","article-title":"Short-term effects of combining upright and prone positions in patients with ARDS: A prospective randomized study","volume":"15","author":"Robak","year":"2011","journal-title":"Crit. 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Intensiv."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/11\/19\/5885\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:46:46Z","timestamp":1760143606000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/11\/19\/5885"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,5]]},"references-count":40,"journal-issue":{"issue":"19","published-online":{"date-parts":[[2022,10]]}},"alternative-id":["jcm11195885"],"URL":"https:\/\/doi.org\/10.3390\/jcm11195885","relation":{},"ISSN":["2077-0383"],"issn-type":[{"type":"electronic","value":"2077-0383"}],"subject":[],"published":{"date-parts":[[2022,10,5]]}}}