{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T05:31:37Z","timestamp":1791869497937,"version":"4.3.4"},"reference-count":23,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2022,10,9]],"date-time":"2022-10-09T00:00:00Z","timestamp":1665273600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Up to 56% of patients develop chronic postsurgical pain (CPSP) after coronary artery bypass grafting (CABG). CPSP can affect patients\u2019 moods and decrease daily activities. The primary aim of this study was to investigate CPSP severity in patients following off-pump (OP) CABG using the Neuropathic Pain Symptom Inventory (NPSI). This was a prospective cohort study conducted in a cardiac surgery department of a teaching hospital. Patients undergoing OP-CABG were enrolled in an erector spinae plane block (ESPB) group (n = 27) or a control (CON) group (n = 24). Before the induction of general anesthesia, ESPB was performed on both sides under ultrasound guidance using 0.375% ropivacaine. The secondary outcomes included cumulative oxycodone consumption, acute pain intensity, mechanical ventilation time, hospital length of stay, and postoperative complications. CPSP intensity was lower in the ESPB group than in the CON group 1, 3, and 6 months post-surgery (p &lt; 0.001). Significant between-group differences were also observed in other outcomes, including postoperative pain severity, opioid consumption, mechanical ventilation time, and hospital length of stay, in favor of the ESPB group. Preemptive ESPB appears to decrease the risk of CPSP development in patients undergoing OP-CABG. Reduced acute pain severity and shorter mechanical ventilation times and hospital stays should improve patients\u2019 satisfaction and reduce perioperative complications.<\/jats:p>","DOI":"10.3390\/jcm11195949","type":"journal-article","created":{"date-parts":[[2022,10,9]],"date-time":"2022-10-09T20:49:31Z","timestamp":1665348571000},"page":"5949","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Erector Spinae Plane Block Decreases Chronic Postoperative Pain Severity in Patients Undergoing Coronary Artery Bypass Grafting"],"prefix":"10.3390","volume":"11","author":[{"given":"Marcin","family":"Wiech","sequence":"first","affiliation":[{"name":"Second Department of Anesthesia and Intensive Therapy, Medical University of Lublin, Staszica 16, 20-081 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3947-3094","authenticated-orcid":false,"given":"S\u0142awomir","family":"\u017burek","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Medical Faculty, University of Rzeszow, Lwowska 60, 35-301 Rzeszow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arkadiusz","family":"Kurowicki","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Medical Faculty, University of Rzeszow, Lwowska 60, 35-301 Rzeszow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beata","family":"Horeczy","sequence":"additional","affiliation":[{"name":"Pro-Familia Hospital, Medical College of Rzeszow University, Witolda 6B, 35-302 Rzeszow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9025-6717","authenticated-orcid":false,"given":"Miros\u0142aw","family":"Czuczwar","sequence":"additional","affiliation":[{"name":"Second Department of Anesthesia and Intensive Therapy, Medical University of Lublin, Staszica 16, 20-081 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8529-484X","authenticated-orcid":false,"given":"Pawe\u0142","family":"Piwowarczyk","sequence":"additional","affiliation":[{"name":"Second Department of Anesthesia and Intensive Therapy, Medical University of Lublin, Staszica 16, 20-081 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9150-8410","authenticated-orcid":false,"given":"Kazimierz","family":"Widenka","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Medical Faculty, University of Rzeszow, Lwowska 60, 35-301 Rzeszow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6183-811X","authenticated-orcid":false,"given":"Micha\u0142","family":"Borys","sequence":"additional","affiliation":[{"name":"Second Department of Anesthesia and Intensive Therapy, Medical University of Lublin, Staszica 16, 20-081 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1161\/CIRCULATIONAHA.116.022572","article-title":"Current practice of state-of-the-art surgical coronary revascularization","volume":"136","author":"Head","year":"2017","journal-title":"Circulation"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1034\/j.1399-6576.2001.450803.x","article-title":"Chronic post-sternotomy pain","volume":"45","author":"Kalso","year":"2001","journal-title":"Acta Anaesthesiol. Scand."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0304-3959(00)00466-8","article-title":"Prevalence and characteristics of post coronary artery bypass graft surgery pain (PCP)","volume":"92","author":"Eisenberg","year":"2001","journal-title":"Pain"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1093\/bja\/aet213","article-title":"Regional anaesthesia to prevent chronic pain after surgery: A Cochrane systematic review and meta-analysis","volume":"111","author":"Andreae","year":"2013","journal-title":"Br. J. Anaesth."},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Borys, M., Hanych, A., and Czuczwar, M. (2020). Paravertebral block versus preemptive ketamine effect on pain intensity after posterolateral thoracotomies: A randomized controlled trial. J. Clin. Med., 9.","DOI":"10.20944\/preprints202002.0093.v1"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1213\/XAA.0000000000000478","article-title":"Continuous erector spinae plane block for rescue analgesia in thoracotomy after epidural failure: A case report","volume":"8","author":"Forero","year":"2017","journal-title":"A A Case. Rep."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"323","DOI":"10.4103\/aca.ACA_16_18","article-title":"Comparison of continuous thoracic epidural analgesia with bilateral erector spinae plane block for perioperative pain management in cardiac surgery","volume":"21","author":"Nagaraja","year":"2018","journal-title":"Ann. Card. Anaesth."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1053\/j.jvca.2018.05.050","article-title":"Bilateral erector spinae plane block for acute post-surgical pain in adult cardiac surgical patients: A randomized controlled trial","volume":"33","author":"Krishna","year":"2019","journal-title":"J. Cardiothorac. Vasc. Anesth."},{"key":"ref_9","first-page":"208","article-title":"Erector spinae-plane block as an analgesic alternative in patients undergoing mitral and\/or tricuspid valve repair through a right mini-thoracotomy\u2014An observational cohort study","volume":"15","author":"Borys","year":"2020","journal-title":"Videosurg. Other Miniinvasive Tech."},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Gaw\u0119da, B., Borys, M., Belina, B., B\u0105k, J., Czuczwar, M., Wo\u0142oszczuk-G\u0119bicka, B., Kolowca, M., and Widenka, K. (2020). Postoperative pain treatment with erector spinae plane block and pectoralis nerve blocks in patients undergoing mitral\/tricuspid valve repair\u2014a randomized controlled trial. BMC Anesthesiol., 20.","DOI":"10.1186\/s12871-020-00961-8"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"10","DOI":"10.5114\/ait.2020.93160","article-title":"Implementation of enhanced recovery after surgery (ERAS) protocol in off-pump coronary artery bypass graft surgery.A prospective cohort feasibility study","volume":"52","author":"Borys","year":"2020","journal-title":"Anaesthesiol. Intensive Ther."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.pain.2003.12.024","article-title":"Development and validation of the neuropathic pain symptom inventory","volume":"108","author":"Bouhassira","year":"2004","journal-title":"Pain"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"257","DOI":"10.5114\/ait.2019.88071","article-title":"Transversus abdominis plane block and quadratus lumborum block did not reduce the incidence or severity of chronic postsurgical pain following cesarean section: A prospective, observational study","volume":"51","author":"Borys","year":"2019","journal-title":"Anaesthesiol. Intensive Ther."},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Borys, M., Zamaro, A., Horeczy, B., G\u0119szka, E., Janiak, M., W\u0119grzyn, P., Czuczwar, M., and Piwowarczyk, P. (2021). Quadratus lumborum and transversus abdominis plane blocks and their impact on acute and chronic pain in patients after cesarean section: A randomized controlled Study. Int. J. Environ. Res. Public Health, 18.","DOI":"10.3390\/ijerph18073500"},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Weinstein, E., Levene, J., Cohen, M., Andreae, D., Chao, J., Johnson, M., Hall, C., and Andreae, M. (2018). Local anaesthetics and regional anaesthesia versus conventional analgesia for preventing persistent postoperative pain in adults and children. Cochrane Database Syst. Rev.","DOI":"10.1002\/14651858.CD007105.pub3"},{"key":"ref_16","first-page":"206","article-title":"Correlation of acute pain treatment to occurrence of chronic pain in tumor patients after thoracotomy","volume":"27","author":"Lu","year":"2008","journal-title":"Aizheng"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1213\/01.ane.0000230603.92574.4e","article-title":"Preincisional paravertebral block reduces the prevalence of chronic pain after breast surgery","volume":"103","author":"Kairaluoma","year":"2006","journal-title":"Anesth. Analg."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Borys, M., Szajowska, P., Jednakiewicz, M., Wita, G., Czarnik, T., Mieszkowski, M., Tuyakov, B., Ga\u0142kin, P., Rahnama-Hezavah, M., and Czuczwar, M. (2021). Quadratus Lumborum Block Reduces Postoperative Opioid Consumption and Decreases Persistent Postoperative Pain Severity in Patients Undergoing Both Open and Laparoscopic Nephrectomies-A Randomized Controlled Trial. J. Clin. Med., 10.","DOI":"10.20944\/preprints202105.0495.v1"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1097\/AAP.0000000000000663","article-title":"Chronic Poststernotomy Pain: Incidence, Risk Factors, Treatment, Prevention, and the Anesthesiologist\u2019s Role","volume":"42","author":"Kleiman","year":"2017","journal-title":"Reg. Anesth. Pain Med."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1097\/ALN.0000000000003837","article-title":"Pharmacotherapy for the Prevention of Chronic Pain after Surgery in Adults: An Updated Systematic Review and Meta-analysis","volume":"135","author":"Carley","year":"2021","journal-title":"Anesthesiology"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1111\/anae.15164","article-title":"Efficacy of erector spinae plane block for analgesia in breast surgery: A systematic review and meta-analysis","volume":"76","author":"Leong","year":"2021","journal-title":"Anaesthesia"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1007\/s12630-020-01793-3","article-title":"Quadratus lumborum block for postoperative analgesia: A systematic review and meta-analysis","volume":"67","author":"Uppal","year":"2020","journal-title":"Can. J. Anaesth."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1053\/j.jvca.2018.11.021","article-title":"Ultrasound-Guided Continuous Thoracic Erector Spinae Plane Block Within an Enhanced Recovery Program Is Associated with Decreased Opioid Consumption and Improved Patient Postoperative Rehabilitation After Open Cardiac Surgery-A Patient-Matched, Controlled Before-and-After Study","volume":"33","author":"Macaire","year":"2019","journal-title":"J. Cardiothorac. Vasc. 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