{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T22:28:15Z","timestamp":1767997695258,"version":"3.49.0"},"reference-count":29,"publisher":"MDPI AG","issue":"20","license":[{"start":{"date-parts":[[2022,10,11]],"date-time":"2022-10-11T00:00:00Z","timestamp":1665446400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Long urethral strictures or even recurrent urethral strictures, mostly with scar tissue showing insufficient healing tendencies, are defined as complex and represent a big challenge in modern reconstructive urology. Initially, the treatment of complicated urethral strictures was associated with a high failure rate (20\u201340%) due to the growth of hair in the neourethra and a lack of sufficient suitable epithelium when scrotal skin was used. Although much effort was put into tissue engineering recently, harvesting and transplanting autologous tissue represent the standard of care for urethral substitution or augmentation. Since 1977, two-staged urethroplasty with the usage of free foreskin or 0.1 mm thick meshed skin from the upper leg was performed in complicated cases and was initially described in 1984 and 1989 by Schreiter and Schreiter and Noll, respectively. In stage 1, the graft is harvested by cutting the skin thinly above the hair follicles and transplanted as a plate around the opened urethra. In stage 2, after 8\u201312 weeks, the neourethra is formed. Success rates of up to 84% are described. Considering the complexity of the strictures in which mesh graft urethroplasty is usually performed, the reachable success rates are outstanding, especially considering that this surgery is most likely the last opportunity to prevent perineostomy or even urinary diversion. This article describes the surgical technique and embeds the mesh graft urethroplasty in today\u2019s literature to underline its importance in the surgical management of complex urethral strictures.<\/jats:p>","DOI":"10.3390\/jcm11205989","type":"journal-article","created":{"date-parts":[[2022,10,11]],"date-time":"2022-10-11T22:18:13Z","timestamp":1665526693000},"page":"5989","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Mesh Graft Urethroplasty\u2014Still a Safe and Promising Technique in Mostly Unpromising Complex Urethral Strictures"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2045-5005","authenticated-orcid":false,"given":"Mathias","family":"Reichert","sequence":"first","affiliation":[{"name":"Department of Urology, Universit\u00e4tsmedizin G\u00f6ttingen, 37099 G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maurizio","family":"Aragona","sequence":"additional","affiliation":[{"name":"Department of Urology, St\u00e4dtisches Klinikum L\u00fcneburg, 21339 L\u00fcneburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmad","family":"Soukkar","sequence":"additional","affiliation":[{"name":"Department of Urology, St\u00e4dtisches Klinikum L\u00fcneburg, 21339 L\u00fcneburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Olianas","sequence":"additional","affiliation":[{"name":"Department of Urology, St\u00e4dtisches Klinikum L\u00fcneburg, 21339 L\u00fcneburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1007\/s00120-006-1031-9","article-title":"Urethralstriktur\u2014Operative Konzepte [Urethral strictures\u2014Operative strategy]","volume":"45","author":"Olianas","year":"2006","journal-title":"Urol. 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