{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T09:10:50Z","timestamp":1787735450427,"version":"build-2784847793"},"reference-count":94,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2022,10,24]],"date-time":"2022-10-24T00:00:00Z","timestamp":1666569600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Over the past two decades, transcatheter aortic valve replacement (TAVR) swiftly evolved from a disrupting technology towards mainstream therapy in the field of severe symptomatic aortic stenosis. A series of randomized evaluations established its role in treating severe aortic stenosis patients across all surgical risk categories, paving the way for an extension of its indications to younger low-risk patients with a longer life expectancy. Therefore, managing comorbidities and limiting procedural complications, which may affect long-term outcomes, is of paramount importance. Among those, new-onset conduction disturbances and concomitant coronary artery disease remain two of the most debated issues. In the present review, we will discuss the incidence, prognostic impact, and unmet needs of patients with post-TAVR new-onset conduction disturbances and the ongoing challenges posed by the management of concomitant coronary artery disease.<\/jats:p>","DOI":"10.3390\/jcm11216256","type":"journal-article","created":{"date-parts":[[2022,10,24]],"date-time":"2022-10-24T06:37:45Z","timestamp":1666593465000},"page":"6256","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Unmet Needs in TAVR: Conduction Disturbances and Management of Coronary Artery Disease"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0535-2120","authenticated-orcid":false,"given":"Vincent","family":"Auffret","sequence":"first","affiliation":[{"name":"CHU Rennes Service de Cardiologie, Universit\u00e9 de Rennes 1, Inserm LTSI U1099, 35000 Rennes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carine","family":"Ridard","sequence":"additional","affiliation":[{"name":"CHU Rennes Service de Cardiologie, Universit\u00e9 de Rennes 1, Inserm LTSI U1099, 35000 Rennes, France"},{"name":"Vivalto Sant\u00e9, Centre Hospitalier Priv\u00e9 St-Gr\u00e9goire, 35760 St-Gr\u00e9goire, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Salerno","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences, Division of Cardiology, Magna Graecia University, 88100 Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabato","family":"Sorrentino","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences, Division of Cardiology, Magna Graecia University, 88100 Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1055\/s-0037-1607457","article-title":"Antithrombotic Treatment after Transcatheter Heart Valves Implant","volume":"44","author":"Sorrentino","year":"2018","journal-title":"Semin. 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