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In recent years there has been an increase in the use of serious games (SG) to address these factors with positive results. The aim of this study was to analyze the efficacy of the intervention with a new SG (e-Estesia), as an adjunct to a CBT intervention for GD. The sample comprised two groups (experimental group (n = 40) and control group (n = 64)) of patients with GD diagnosis. Both groups received 16 weekly CBT sessions and, concurrently, only the experimental group received 15 additional sessions with e-Estesia. Pre-post treatment with e-Estesia administered in both groups were: DSM-5 Criteria, South Oaks Gambling Screen, Symptom Checklist-Revised and measure of relapses, dropout and compliance of treatment. As regards the experimental group were also administered: Difficulties in Emotion Regulation Scale, Emotion Regulation Questionnaire, and Impulsive Behavior Scale. No statistically significant differences in the general psychopathological state, emotion regulation or impulsivity were found when comparing the groups. However, patients enrolled in the e-Estesia intervention had significantly less relapses and better indicators of treatment compliance than the control group. Considering these results, the use of complementary tools such as SG are useful for addressing GD.<\/jats:p>","DOI":"10.3390\/jcm11226798","type":"journal-article","created":{"date-parts":[[2022,11,17]],"date-time":"2022-11-17T06:19:01Z","timestamp":1668665941000},"page":"6798","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["e-Estesia: A Serious Game for Reducing Arousal, Improving Emotional Regulation and Increasing Wellbeing in Individuals with Gambling Disorder"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4172-9714","authenticated-orcid":false,"given":"Teresa","family":"Mena-Moreno","sequence":"first","affiliation":[{"name":"Department of Psychiatry, University Hospital of Bellvitge, Bellvitge Institute for Biomedical Research (IDIBELL), 08907 Barcelona, Spain"},{"name":"Ciber Fisiopatolog\u00eda Obesidad y Nutrici\u00f3n (CIBERObn), Instituto de Salud Carlos III, 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Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9426-5082","authenticated-orcid":false,"given":"Ignacio","family":"Lucas","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University Hospital of Bellvitge, Bellvitge Institute for Biomedical Research (IDIBELL), 08907 Barcelona, Spain"},{"name":"Ciber Fisiopatolog\u00eda Obesidad y Nutrici\u00f3n (CIBERObn), Instituto de Salud Carlos III, 28029 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2968-9898","authenticated-orcid":false,"given":"Fernando","family":"Fern\u00e1ndez-Aranda","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University Hospital of Bellvitge, Bellvitge Institute for Biomedical Research (IDIBELL), 08907 Barcelona, Spain"},{"name":"Ciber Fisiopatolog\u00eda Obesidad y Nutrici\u00f3n (CIBERObn), Instituto de Salud Carlos III, 28029 Madrid, 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