{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T23:44:45Z","timestamp":1788997485783,"version":"build-2803163510"},"reference-count":44,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2022,11,19]],"date-time":"2022-11-19T00:00:00Z","timestamp":1668816000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Cablon Medical"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Iron deficiency (ID) and anemia in patients with Inflammatory Bowel Disease (IBD) are associated with a reduced quality of life. We assessed the prevalence of ID and anemia in Dutch outpatients with IBD and compared routine ID(A) management among medical professionals to the European Crohn\u2019s and Colitis Organisation (ECCO) treatment guidelines. Methods: Between January and November 2021, consecutive adult outpatients with IBD were included in this study across 16 Dutch hospitals. Clinical and biochemical data were extracted from medical records. Additionally, medical professionals filled out questionnaires regarding routine ID(A) management. Results: In total, 2197 patients (1271 Crohn\u2019s Disease, 849 Ulcerative Colitis, and 77 IBD-unclassified) were included. Iron parameters were available in 59.3% of cases. The overall prevalence of anemia, ID, and IDA was: 18.0%, 43.4%, and 12.2%, respectively. The prevalence of all three conditions did not differ between IBD subtypes. ID(A) was observed more frequently in patients with biochemically active IBD than in quiescent IBD (ID: 70.8% versus 23.9%; p &lt; 0.001). Contrary to the guidelines, most respondents prescribed standard doses of intravenous or oral iron regardless of biochemical parameters or inflammation. Lastly, 25% of respondents reported not treating non-anemic ID. Conclusions: One in five patients with IBD suffers from anemia that\u2014despite inconsistently measured iron parameters\u2014is primarily caused by ID. Most medical professionals treat IDA with oral iron or standard doses of intravenous iron regardless of biochemical inflammation; however, non-anemic ID is often overlooked. Raising awareness about the management of ID(A) is needed to optimize and personalize routine care.<\/jats:p>","DOI":"10.3390\/jcm11226843","type":"journal-article","created":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T04:33:32Z","timestamp":1669005212000},"page":"6843","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Anemia and Iron Deficiency in Outpatients with Inflammatory Bowel Disease: Ubiquitous Yet Suboptimally Managed"],"prefix":"10.3390","volume":"11","author":[{"given":"Roberta","family":"Loveikyte","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden University, 2333 ZA Leiden, The Netherlands"},{"name":"Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Menno","family":"Boer","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden University, 2333 ZA Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catharina N.","family":"van der Meulen","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden University, 2333 ZA Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rinze W. F.","family":"ter Steege","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Martini Hospital, 9728 NT Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greetje","family":"Tack","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Medical Center Leeuwarden, 8934 AD Leeuwarden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6802-360X","authenticated-orcid":false,"given":"Johan","family":"Kuyvenhoven","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Spaarne Gasthuis Hospital, 2000 AK Haarlem, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bindia","family":"Jharap","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Meander Medical Center, 3813 TZ Amersfoort, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"My K.","family":"Vu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Alrijne Hospital, 2350 CC Leiderdorp, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauran","family":"Vogelaar","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Diakonessenhuis Hospital, 3582 KE Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel L.","family":"West","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Franciscus Gasthuis & Vlietland Hospital, 3004 BA Rotterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sander","family":"van der Marel","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Haaglanden Medical Center, 2512 VA The Hague, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tessa E. H.","family":"R\u00f6mkens","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Jeroen Bosch Hospital, 5223 GZ Den Bosch, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5211-0381","authenticated-orcid":false,"given":"Zlatan","family":"Mujagic","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Maastricht University Medical Center+, Maastricht University, 6229 HX Maastricht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5314-4452","authenticated-orcid":false,"given":"Frank","family":"Hoentjen","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Radboud University Medical Center, Radboud University, 6525 GA Nijmegen, The Netherlands"},{"name":"Division of Gastroenterology, University of Alberta, Edmonton, AB T6G 2X8, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2636-303X","authenticated-orcid":false,"given":"Adriaan A.","family":"van Bodegraven","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Geriatrics, Internal- and Intensive Care Medicine (COMIK), Zuyderland Medical Center, 6130 MB Sittard-Geleen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fiona D. M.","family":"van Schaik","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht University, 3584 CX Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annemarie C.","family":"de Vries","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Erasmus University Rotterdam, 3015 GD Rotterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4563-7462","authenticated-orcid":false,"given":"Gerard","family":"Dijkstra","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea E.","family":"van der Meulen-de Jong","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden University, 2333 ZA Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,11,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1111\/j.1365-2036.2006.03146.x","article-title":"Systematic review: Managing anaemia in crohn\u2019s disease","volume":"24","author":"Kulnigg","year":"2006","journal-title":"Aliment. Pharmacol. Ther."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"44s","DOI":"10.1016\/j.amjmed.2003.12.011","article-title":"Prevalence and outcomes of anemia in inflammatory bowel disease: A systematic review of the literature","volume":"116","author":"Wilson","year":"2004","journal-title":"Am. J. Med."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"S6","DOI":"10.1111\/hdi.12542","article-title":"Overview of iron metabolism in health and disease","volume":"21","author":"Dev","year":"2017","journal-title":"Hemodial. Int."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/anae.15432","article-title":"The misogyny of iron deficiency","volume":"76","author":"Dugan","year":"2021","journal-title":"Anaesthesia"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1136\/gut.2003.035758","article-title":"Iron, anaemia, and inflammatory bowel diseases","volume":"53","author":"Gasche","year":"2004","journal-title":"Gut"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1097\/MIB.0000000000000768","article-title":"Iron deficiency in the absence of anemia impairs the perception of health-related quality of life of patients with inflammatory bowel disease","volume":"22","author":"Casellas","year":"2016","journal-title":"Inflamm. Bowel Dis."},{"key":"ref_7","first-page":"22","article-title":"Prevalence of iron deficiency without anaemia in inflammatory bowel disease and impact on health-related quality of life","volume":"41","author":"Crespo","year":"2018","journal-title":"Gastroenterol. Hepatol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"S343","DOI":"10.14309\/00000434-201810001-00599","article-title":"Half of IBD patients without anemia have iron deficiency leading to similar rates of fatigue as iron deficiency anemia: 599","volume":"113","author":"Thuluvath","year":"2018","journal-title":"Off. J. Am. Coll. Gastroenterol.|ACG"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1002\/ibd.20925","article-title":"Oral and intravenous iron treatment in inflammatory bowel disease: Hematological response and quality of life improvement","volume":"15","author":"Gisbert","year":"2009","journal-title":"Inflamm. Bowel Dis."},{"key":"ref_10","first-page":"199","article-title":"High-dose intravenous treatment in iron deficiency anaemia in inflammatory bowel disease: Early efficacy and impact on quality of life","volume":"14","author":"Bocos","year":"2016","journal-title":"Blood Transfus."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1093\/ecco-jcc\/jju009","article-title":"European consensus on the diagnosis and management of iron deficiency and anaemia in inflammatory bowel diseases","volume":"9","author":"Dignass","year":"2015","journal-title":"J. Crohn\u2019s Colitis"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1111\/apt.15739","article-title":"Comparative accuracy of ferritin, transferrin saturation and soluble transferrin receptor for the diagnosis of iron deficiency in inflammatory bowel disease","volume":"51","author":"Daude","year":"2020","journal-title":"Aliment. Pharmacol. Ther."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1111\/apt.15833","article-title":"Letter: Assessing iron deficiency in patients with IBD-a step in the right direction, but uncertainty remains","volume":"52","author":"Garg","year":"2020","journal-title":"Aliment. Pharmacol. Ther."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1111\/joim.13503","article-title":"Iron deficiency screening is a key issue in chronic inflammatory diseases: A call to action","volume":"292","author":"Cacoub","year":"2022","journal-title":"J. Intern. Med."},{"key":"ref_15","unstructured":"Gulhar, R., Ashraf, M.A., and Jialal, I. (2021). Physiology, acute phase reactants. StatPearls. Treasure Island (FL): StatPearls Publishing Copyright \u00a9 2021, StatPearls Publishing LLC."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Mahalhal, A., Burkitt, M., Duckworth, C., Hold, G., Campbell, B., Pritchard, D., and Probert, C. (2021). Long-term iron deficiency and dietary iron excess exacerbate acute dextran sodium sulphate-induced colitis and are associated with significant dysbiosis. Int. J. Mol. Sci., 22.","DOI":"10.3390\/ijms22073646"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"5a","DOI":"10.1155\/2005\/269076","article-title":"Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: Report of a working party of the 2005 montreal world congress of gastroenterology","volume":"19","author":"Silverberg","year":"2005","journal-title":"Can. J. Gastroenterol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1136\/gut.2005.082909","article-title":"The montreal classification of inflammatory bowel disease: Controversies, consensus, and implications","volume":"55","author":"Satsangi","year":"2006","journal-title":"Gut"},{"key":"ref_19","unstructured":"Hooijkaas, H.M.K., Souverijn, J.H.M., and Smeets, L.C. (2013). Tax GHM Handboek Medische Laboratoriumdiagnostiek, Prelum Uitgevers."},{"key":"ref_20","unstructured":"Nederlands Huisartsen Genootschap (2022, October 18). Laboratoriumdiagnostiek Vitamine B12-Defici\u00ebntie (LESA). Available online: https:\/\/www.nhg.org\/themas\/publicaties\/laboratoriumdiagnostiek-vitamine-b12-volledige-tekst."},{"key":"ref_21","unstructured":"Nederlandse Vereniging voor Klinische Chemie en Laboratoriumgeneeskunde (2022, October 18). Algemeen Overzicht Referentiewaarden. Available online: https:\/\/www.nvkc.nl\/algemeen-overzicht-referentiewaarden."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.dld.2015.10.012","article-title":"The burden of anaemia in patients with inflammatory bowel diseases","volume":"48","author":"Testa","year":"2016","journal-title":"Dig. Liver Dis."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1016\/j.crohns.2010.07.008","article-title":"Prevalence of anaemia in inflammatory bowel disease in Switzerland: A cross-sectional study in patients from private practices and university hospitals","volume":"4","author":"Voegtlin","year":"2010","journal-title":"J. Crohn\u2019s Colitis"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"304","DOI":"10.3109\/00365521.2010.533382","article-title":"The prevalence of anemia and iron deficiency in IBD outpatients in Scandinavia","volume":"46","author":"Bager","year":"2011","journal-title":"Scand. J. Gastroenterol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1097\/01.MIB.0000442728.74340.fd","article-title":"Prevalence of anemia in inflammatory bowel diseases in european countries: A systematic review and individual patient data meta-analysis","volume":"20","author":"Filmann","year":"2014","journal-title":"Inflamm. Bowel Dis."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1111\/apt.14920","article-title":"Incidence, prevalence and clinical outcome of anaemia in inflammatory bowel disease: A population-based cohort study","volume":"48","author":"Eriksson","year":"2018","journal-title":"Aliment. Pharmacol. Ther."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1590\/s0004-2803.202000000-51","article-title":"Anemia and iron deficiency in inflammatory bowel disease patients in a referral center in Brazil: Prevalence and risk factors","volume":"57","author":"Parra","year":"2020","journal-title":"Arq. Gastroenterol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"5637","DOI":"10.1007\/s10620-022-07474-z","article-title":"Iron deficiency in patients with inflammatory bowel diseases: A prospective multicenter cross-sectional study","volume":"67","author":"Bouguen","year":"2022","journal-title":"Dig. Dis. Sci."},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Bergamaschi, G., Castiglione, F., D\u2019Inc\u00e0, R., Astegiano, M., Fries, W., Milla, M., Ciacci, C., Rizzello, F., Saibeni, S., and Ciccocioppo, R. (2022). Prevalence, pathogenesis and management of anemia in inflammatory bowel disease: An IG-IBD multicenter, prospective, and observational study. Inflamm. Bowel Dis., izac054.","DOI":"10.1093\/ibd\/izac054"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"199","DOI":"10.3324\/haematol.2009.009985","article-title":"Prevalence and pathogenesis of anemia in inflammatory bowel disease. Influence of anti-tumor necrosis factor- treatment","volume":"95","author":"Bergamaschi","year":"2010","journal-title":"Haematologica"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1111\/apt.12541","article-title":"Anaemia in inflammatory bowel disease: A population-based 10-year follow-up","volume":"39","author":"Reinisch","year":"2014","journal-title":"Aliment. Pharmacol. Ther."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.dld.2016.12.005","article-title":"Anemia at the time of diagnosis of inflammatory bowel disease: Prevalence and associated factors in adolescent and adult patients","volume":"49","author":"Lucendo","year":"2017","journal-title":"Dig. Liver. Dis."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"4186","DOI":"10.3748\/wjg.v24.i36.4186","article-title":"Frequency, types, and treatment of anemia in Turkish patients with inflammatory bowel disease","volume":"24","author":"Bengi","year":"2018","journal-title":"World J. Gastroenterol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1093\/ibd\/izy054","article-title":"The Relevance of Vitamin and Iron Deficiency in Patients with Inflammatory Bowel Diseases in Patients of the Swiss IBD Cohort","volume":"24","author":"Madanchi","year":"2018","journal-title":"Inflamm. Bowel Dis."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"15","DOI":"10.15403\/jgld.2014.1121.lpu","article-title":"Prevalence of anemia and iron deficiency in romanian patients with inflammatory bowel disease: A prospective multicenter study","volume":"24","author":"Lupu","year":"2015","journal-title":"J. Gastrointest. Liver Dis."},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Foteinogiannopoulou, K., Karmiris, K., Axiaris, G., Velegraki, M., Gklavas, A., Kapizioni, C., Karageorgos, C., Kateri, C., Katsoula, A., and Kokkotis, G. (2021). The burden and management of anemia in Greek patients with inflammatory bowel disease: A retrospective, multicenter, observational study. BMC Gastroenterol., 21.","DOI":"10.1186\/s12876-021-01826-1"},{"key":"ref_37","unstructured":"World Health Organization (2022, November 09). Haemoglobin Concentrations for the Diagnosis of Anaemia and Assessment of Severity. Published 2011. Available online: https:\/\/apps.who.int\/iris\/bitstream\/handle\/10665\/85839\/WHO_NMH_NHD_MNM_11.1_eng.pdf?ua=1."},{"key":"ref_38","unstructured":"Rokkam, V.R., and Kotagiri, R. (2022). Secondary thrombocytosis. StatPearls. Treasure Island (FL): StatPearls Publishing Copyright \u00a9 2022, StatPearls Publishing LLC."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1097\/MEG.0b013e328365ca7f","article-title":"Anaemia management in patients with inflammatory bowel disease: Routine practice across nine European countries","volume":"25","author":"Stein","year":"2013","journal-title":"Eur. J. Gastroenterol. Hepatol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"116202","DOI":"10.1016\/j.bone.2021.116202","article-title":"Hypophosphatemia after intravenous iron therapy: Comprehensive review of clinical findings and recommendations for management","volume":"154","author":"Schaefer","year":"2022","journal-title":"Bone"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.3324\/haematol.2019.220830","article-title":"Iron absorption from supplements is greater with alternate day than with consecutive day dosing in iron-deficient anemic women","volume":"105","author":"Stoffel","year":"2020","journal-title":"Haematologica"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"e524","DOI":"10.1016\/S2352-3026(17)30182-5","article-title":"Iron absorption from oral iron supplements given on consecutive versus alternate days and as single morning doses versus twice-daily split dosing in iron-depleted women: Two open-label, randomised controlled trials","volume":"4","author":"Stoffel","year":"2017","journal-title":"Lancet Haematol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"3531","DOI":"10.1007\/s12325-021-01770-2","article-title":"Intravenous iron-induced hypophosphatemia: An emerging syndrome","volume":"38","author":"Glaspy","year":"2021","journal-title":"Adv. Ther."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1111\/j.1572-0241.2008.01846.x","article-title":"Common misconceptions in the diagnosis and management of anemia in inflammatory bowel disease","volume":"103","author":"Gisbert","year":"2008","journal-title":"Am. J. Gastroenterol."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/11\/22\/6843\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:22:03Z","timestamp":1760145723000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/11\/22\/6843"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,19]]},"references-count":44,"journal-issue":{"issue":"22","published-online":{"date-parts":[[2022,11]]}},"alternative-id":["jcm11226843"],"URL":"https:\/\/doi.org\/10.3390\/jcm11226843","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,19]]}}}