{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:50:29Z","timestamp":1787028629359,"version":"build-2736575974"},"reference-count":24,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2022,11,20]],"date-time":"2022-11-20T00:00:00Z","timestamp":1668902400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: In recent years, several actions have been made to shorten the chain of survival in out-of-hospital cardiac arrest (OHCA). These include placing defibrillators in public places, training first responders, and providing dispatcher-assisted CPR (DA-CPR). In this work, we aimed to evaluate the impact of these changes on patients\u2019 outcomes, including achieving return of spontaneous circulation (ROSC), survival to discharge, and survival with favorable neurological function. Methods: We retrospectively retrieved data of all calls to the national emergency medical service in Ashdod city, Israel, of individuals who underwent OHCA at the age of 18 and older between the years 2018 and 2021. Data was collected on prehospital and hospital interventions. The association between pre-hospital and hospital interventions to ROSC, survival to discharge, and neurological outcomes was evaluated. Logistic regression was used for multivariable analysis. Results: During the years 2018\u20132021, there were 1253 OHCA cases in the city of Ashdod. ROSC was achieved in 207 cases (32%), survival to discharge was attained in 48 cases (7.4%), and survival with favorable neurological function was obtained in 26 cases (4%). Factors significantly associated with good prognosis were shockable rhythm, witnessed arrest, DA-CPR, use of AED, and treatment for STEMI. All patients that failed to achieve ROSC outside of the hospital setting had a poor prognosis. Conclusions: This study demonstrates the prognostic role of the initial rhythm and the use of AED in OHCA. Hospital management, including STEMI documentation and catheterization, was also an important prognostication factors. Additionally, when ROSC is not achieved in the field, hospital transfer should be considered.<\/jats:p>","DOI":"10.3390\/jcm11226851","type":"journal-article","created":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T04:33:32Z","timestamp":1669005212000},"page":"6851","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["The Impact of Prehospital and Hospital Care on Clinical Outcomes in Out-of-Hospital Cardiac Arrest"],"prefix":"10.3390","volume":"11","author":[{"given":"Yotam","family":"Deri","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine Assuta Ashdod Hospital, Ashdod 7747629, Israel"},{"name":"Goldman Medical School, Ben-Gurion University of the Negev, Be\u2019er Sheva 8410501, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baruch","family":"Berzon","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Assuta Ashdod Hospital, Ashdod 7747629, Israel"},{"name":"Goldman Medical School, Ben-Gurion University of the Negev, Be\u2019er Sheva 8410501, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debra","family":"West","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Assuta Ashdod Hospital, Ashdod 7747629, Israel"},{"name":"Goldman Medical School, Ben-Gurion University of the Negev, Be\u2019er Sheva 8410501, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matan","family":"Machloof","sequence":"additional","affiliation":[{"name":"Goldman Medical School, Ben-Gurion University of the Negev, Be\u2019er Sheva 8410501, Israel"},{"name":"Internal Medicine B, Assuta Ashdod Hospital, Ashdod 7747629, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Refael","family":"Strugo","sequence":"additional","affiliation":[{"name":"Magen David Adom, Ha-Refu\u2019a St 1, Ashdod 6021805, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomer","family":"Kaplan","sequence":"additional","affiliation":[{"name":"Magen David Adom, Ha-Refu\u2019a St 1, Ashdod 6021805, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shelly","family":"Soffer","sequence":"additional","affiliation":[{"name":"Goldman Medical School, Ben-Gurion University of the Negev, Be\u2019er Sheva 8410501, Israel"},{"name":"Internal Medicine B, Assuta Ashdod Hospital, Ashdod 7747629, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,11,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1016\/j.resuscitation.2010.08.006","article-title":"Global incidences of out-of-hospital cardiac arrest and survival rates: Systematic review of 67 prospective studies","volume":"81","author":"Berdowski","year":"2010","journal-title":"Resuscitation"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/s13054-020-2773-2","article-title":"The global survival rate among adult out-of-hospital cardiac arrest patients who received cardiopulmonary resuscitation: A systematic review and meta-analysis","volume":"24","author":"Yan","year":"2020","journal-title":"Crit. 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