{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T23:44:10Z","timestamp":1782258250084,"version":"3.54.5"},"reference-count":27,"publisher":"MDPI AG","issue":"23","license":[{"start":{"date-parts":[[2022,11,25]],"date-time":"2022-11-25T00:00:00Z","timestamp":1669334400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Korsakoff syndrome (KS) is a severe neuropsychiatric syndrome derived from acute thiamine deficiency and concomitant alcohol use disorders. KS patients need lifelong assistance because of the severity of their cognitive problems. In clinical practice and research, errorless learning has proven to be an effective cognitive rehabilitation method for patients with KS. Our study focused on optimizing errorless learning by introducing new software technology to support the training process of errorless learning. Although the benefits of errorless learning for patients with Korsakoff\u2019s syndrome have been thoroughly investigated, it is currently unclear whether new technology could contribute to better learning and maintenance of everyday tasks. Therefore, an errorless learning application was built. This device is a web application and can be used on a tablet, laptop, or smartphone. The application allows clinicians and researchers to insert pictures, videoclips, timers, and audio fragments in the different steps of an errorless learning training plan. This way, the different steps are visible and easy to follow for patients. Moreover, it ensures as a learning method that the training is executed exactly the same way for each and every training. The aim of this study was twofold: to examine whether the use of the errorless learning application is effective, and whether it leads to better results than a regular errorless learning of everyday activities. In total, 13 patients with KS were trained in instrumental activities of daily living by means of the application, and 10 patients were trained with traditional instructions. Results showed an equal improvement for both training methods. Importantly, the technology group could better remember the training when probed at a later moment than the traditional errorless learning group. These results are promising for further development of novel technology to support errorless learning applications in clinical practice.<\/jats:p>","DOI":"10.3390\/jcm11236947","type":"journal-article","created":{"date-parts":[[2022,11,25]],"date-time":"2022-11-25T03:34:24Z","timestamp":1669347264000},"page":"6947","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The Use of an Errorless Learning Application to Support Re-Learning of (Instrumental) Activities for People Living with Korsakoff Syndrome"],"prefix":"10.3390","volume":"11","author":[{"given":"Roeline","family":"Biemond","sequence":"first","affiliation":[{"name":"Experimental Psychology, Helmholtz Institute, Utrecht University, 3584 CS Utrecht, The Netherlands"},{"name":"Amsta, Cluster Korsakoff, 1052 LS Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4441-0365","authenticated-orcid":false,"given":"Erik","family":"Oudman","sequence":"additional","affiliation":[{"name":"Experimental Psychology, Helmholtz Institute, Utrecht University, 3584 CS Utrecht, The Netherlands"},{"name":"Slingedael Korsakoff Center, Lelie Care Group, 3086 EZ Rotterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Postma","sequence":"additional","affiliation":[{"name":"Experimental Psychology, Helmholtz Institute, Utrecht University, 3584 CS Utrecht, The Netherlands"},{"name":"Slingedael Korsakoff Center, Lelie Care Group, 3086 EZ Rotterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,11,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1093\/alcalc\/agn118","article-title":"The Korsakoff syndrome: Clinical aspects, psychology and treatment","volume":"44","author":"Kopelman","year":"2009","journal-title":"Alcohol. Alcohol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"2875","DOI":"10.2147\/NDT.S130078","article-title":"Korsakoff\u2019s syndrome: A critical review","volume":"13","author":"Arts","year":"2017","journal-title":"Neuropsychiatr. Dis. Treat."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s11065-012-9197-y","article-title":"Remote memory function and dysfunction in Korsakoff\u2019s syndrome","volume":"22","author":"Race","year":"2012","journal-title":"Neuropsychol. Rev."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1080\/13803395.2016.1248811","article-title":"Personal semantic and episodic autobiographical memories in Korsakoff syndrome: A comparison of interview methods","volume":"39","author":"Rensen","year":"2017","journal-title":"J. Clin. Exp. Neuropsychol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1007\/s11065-012-9204-3","article-title":"Implicit memory in Korsakoff\u2019s syndrome: A review of procedural learning and priming studies","volume":"22","author":"Hayes","year":"2012","journal-title":"Neuropsychol. Rev."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1007\/s11065-015-9288-7","article-title":"Procedural learning and memory rehabilitation in Korsakoff\u2019s syndrome-a review of the literature","volume":"25","author":"Oudman","year":"2015","journal-title":"Neuropsychol. Rev."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11065-008-9051-4","article-title":"Errorless learning in the rehabilitation of memory impairment: A critical review","volume":"18","author":"Clare","year":"2008","journal-title":"Neuropsychol. Rev."},{"key":"ref_8","first-page":"1177","article-title":"Errorless learning of everyday tasks in people with dementia","volume":"8","author":"Boelen","year":"2013","journal-title":"Clin. Interv. Aging"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"2867","DOI":"10.2147\/NDT.S140950","article-title":"The effect of errorless learning on quality of life in patients with Korsakoff\u2019s syndrome","volume":"13","author":"Rensen","year":"2017","journal-title":"Neuropsychiatr. Dis. Treat."},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Scheper, I., Kessels, R.P., Brazil, I.A., and Bertens, D. (2021). Errorless and trial-and-error learning of object locations in patients with executive deficits after brain injury. Neuropsychol. Rehabil., 1\u201313.","DOI":"10.1080\/09602011.2021.1997765"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1080\/09658211.2019.1661493","article-title":"The impact of error frequency on errorless and errorful learning of object locations using a novel paradigm","volume":"27","author":"Scheper","year":"2019","journal-title":"Memory"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1076\/1380-3395(200002)22:1;1-8;FT132","article-title":"Intervening with everyday memory problems in dementia of Alzheimer type: An errorless learning approach","volume":"22","author":"Clare","year":"2000","journal-title":"J. Clin. Exp. Neuropsychol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1080\/096020100389200","article-title":"Errorless and effortful processes involved in the learning of face-name associations by patients with alcoholic Korsakoff\u2019s syndrome","volume":"10","author":"Komatsu","year":"2000","journal-title":"Neuropsychol. Rehabil."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1080\/09602011.2013.835738","article-title":"Acquisition of an instrumental activity of daily living in patients with Korsakoff\u2019s syndrome: A comparison of trial and error and errorless learning","volume":"23","author":"Oudman","year":"2013","journal-title":"Neuropsychol. Rehabil."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1080\/09602011.2017.1379419","article-title":"Errorless (re) learning of everyday activities in patients with Korsakoff\u2019s syndrome: A feasibility study","volume":"29","author":"Rensen","year":"2017","journal-title":"Neuropsychol. Rehabil."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1017\/S1041610218000492","article-title":"The effect of errorless learning on psychotic and affective symptoms, as well as aggression and apathy in patients with Korsakoff\u2019s syndrome in long-term care facilities","volume":"31","author":"Rensen","year":"2019","journal-title":"Int. Psychogeriatr."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1017\/S1041610221000016","article-title":"Are people with mild dementia able to (re) learn how to use technology? A literature review","volume":"34","author":"Kerkhof","year":"2022","journal-title":"Int. Psychogeriatr."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1080\/17483107.2020.1765420","article-title":"Randomized controlled feasibility study of FindMyApps: First evaluation of a tablet-based intervention to promote self-management and meaningful activities in people with mild dementia","volume":"17","author":"Kerkhof","year":"2022","journal-title":"Disabil. Rehabil. Assist. Technol."},{"key":"ref_19","first-page":"CD009627","article-title":"Assistive technology for memory support in dementia","volume":"6","author":"Wenborn","year":"2017","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1080\/09602011.2013.814573","article-title":"Impact of SenseCam on memory, identity and mood in Korsakoff\u2019s syndrome: A single case experimental design study","volume":"24","author":"Svanberg","year":"2014","journal-title":"Neuropsychol. Rehabil."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1080\/13554794.2019.1602145","article-title":"Smartwatch aids time-based prospective memory in Korsakoff syndrome: A case study","volume":"25","author":"Lloyd","year":"2019","journal-title":"Neurocase"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1080\/13554794.2021.2024237","article-title":"Smartwatch reminders are as effective as verbal reminders in patients with Korsakoff\u2019s syndrome: Three case studies","volume":"28","author":"Smits","year":"2022","journal-title":"Neurocase"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1192\/bjp.179.1.85-a","article-title":"Diagnostic and statistical manual of mental disorders (4th edn, text revision)(DSM\u2013IV\u2013TR) American Psychiatric Association: Washington, DC, USA, 2000;. ISBN 0 89042 025 4","volume":"179","author":"Cooper","year":"2001","journal-title":"Br. J. Psychiatry"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"2152","DOI":"10.1093\/brain\/awf229","article-title":"Disorders of memory","volume":"125","author":"Kopelman","year":"2002","journal-title":"Brain"},{"key":"ref_25","unstructured":"Wechsler, D. (2012). Wechsler Preschool and Primary Scale of Intelligence, The Psychological Corporation. [4th ed.]. Dutch Version."},{"key":"ref_26","unstructured":"Cascella, M., and Al Khalili, Y. (2021). Short Term Memory Impairment, StatPearls Publishing. 21 July 2021."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"446","DOI":"10.3109\/11038128.2013.821161","article-title":"Use of an electronic cognitive aid by a person with Korsakoff syndrome","volume":"20","author":"Hartjes","year":"2013","journal-title":"Scand. J. Occup. Ther."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/11\/23\/6947\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:26:30Z","timestamp":1760145990000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/11\/23\/6947"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,25]]},"references-count":27,"journal-issue":{"issue":"23","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["jcm11236947"],"URL":"https:\/\/doi.org\/10.3390\/jcm11236947","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,25]]}}}