{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T20:04:13Z","timestamp":1782504253343,"version":"3.54.5"},"reference-count":26,"publisher":"MDPI AG","issue":"23","license":[{"start":{"date-parts":[[2022,11,30]],"date-time":"2022-11-30T00:00:00Z","timestamp":1669766400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81300858"],"award-info":[{"award-number":["81300858"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Purpose: The purpose of this study is to analyze the change and stability of mandibular morphology in patients with asymmetric mandibular prognathism after bilateral sagittal split ramus osteotomy (BSSRO). Methods: We retrospectively analyzed fifty patients with asymmetric mandibular prognathism from the West China Hospital of Stomatology, Sichuan University, between January 2018 to March 2021. The spiral CT data before surgery, within two weeks after surgery, and at more than six months after surgery of each patient were collected. According to the deflection direction of the chin, the bilateral mandibles were defined as the long side and the short side. The morphological data of the bilateral condyle, the mandibular ramus, and the mandibular body were analyzed to determine the effect and stability of BSSRO on asymmetric mandibular prognathism. Results: It was found that the long-side mandible had greater condylar volume and diameter, mandibular ramus height and volume, and mandibular body length and volume (p &lt; 0.05) before surgery. After surgery, the volume of the mandibular ramus increased, while the length and volume of the mandibular body decreased (p &lt; 0.05) at the long side of the mandible; the morphological changes of the mandibular ramus and body at the short side of the mandible were not statistically significant (p &gt; 0.05). When comparing the long and short sides of the mandible, the long side still had greater height and volume of the mandibular ramus (p &lt; 0.01). The volume difference of the mandibular body from the two sides was corrected (p &gt; 0.05), and the length difference of the mandibular body from the two sides was overcorrected (p &lt; 0.05). At more than six months after surgery, the volume of the mandibular ramus and body increased, while their height decreased at the long side of the mandible (p &lt; 0.05). For the other side, or the short side, the volume of the ramus and body increased, too. However, their height decreased (p &lt; 0.01). Conclusion: The results of this study suggested good effect and stability of BSSRO on asymmetric mandibular prognathism, except for the correction of ramus height and volume.<\/jats:p>","DOI":"10.3390\/jcm11237131","type":"journal-article","created":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T02:24:46Z","timestamp":1669861486000},"page":"7131","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["BSSRO Improves Mandibular Morphology Mainly through Correction of Body Length and Volume in Patients with Asymmetric Mandibular Prognathism"],"prefix":"10.3390","volume":"11","author":[{"given":"Yanfei","family":"Liu","sequence":"first","affiliation":[{"name":"State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Orthognathic & TMJ Surgery Center, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunfeng","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Orthognathic & TMJ Surgery Center, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,11,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1016\/j.joms.2009.12.007","article-title":"Motivating factors for patients undergoing orthognathic surgery evaluation","volume":"68","author":"Proothi","year":"2010","journal-title":"J. Oral Maxillofac. Surg."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"4103905","DOI":"10.1155\/2017\/4103905","article-title":"Impact of Orthognathic Surgery on Quality of Life in Patients with Dentofacial Deformities","volume":"2017","author":"Eslamipour","year":"2017","journal-title":"Int. J. Dentistry."},{"key":"ref_3","first-page":"806","article-title":"Spectrum and management of dentofacial deformities in a multiethnic Asian population","volume":"76","author":"Ming","year":"2006","journal-title":"Angle Orthod."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.oooo.2017.01.009","article-title":"Changes in condylar position after BSSRO with and without Le Fort I osteotomy via surgery-first approach in mandibular prognathism with facial asymmetry","volume":"123","author":"Li","year":"2017","journal-title":"Oral Surg. Oral Med. Oral Pathol. Oral Radio"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.ijom.2005.01.007","article-title":"Stabilisation of sagittal split set-back osteotomies with miniplates: A prospective, multicentre study with 2-year follow-up","volume":"34","author":"Borstlap","year":"2005","journal-title":"Int. J. Oral Maxillofac. Surg."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/0278-2391(89)90276-0","article-title":"Factors contributing to relapse in rigidly fixed mandibular setbacks","volume":"47","author":"Je","year":"1989","journal-title":"J. Oral Maxillofac. Surg."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/j.ajodo.2005.02.021","article-title":"Maxillofacial 3-dimensional Image Analysis for the Diagnosis of Facial Asymmetry","volume":"130","author":"Hwang","year":"2006","journal-title":"Am. J. Orthod. Dentofac."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"085018","DOI":"10.1088\/1361-6560\/ab7a71","article-title":"Learning-based local-to-global landmark annotation for automatic 3D cephalometry","volume":"65","author":"Yun","year":"2020","journal-title":"Phys. Med. Bio."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"2143","DOI":"10.1016\/j.joms.2011.08.028","article-title":"Do Patients Treated with Bimaxillary Surgery Have More Stable Condylar Positions than Those Who Have Undergone Single-Jaw Surgery?","volume":"70","author":"Kim","year":"2012","journal-title":"J. Oral Maxillofac. Surg."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.ajodo.2017.08.024","article-title":"Three-dimensional computed tomography analysis of mandibular morphology in patients with facial a symmetry and mandibular retrognathism","volume":"153","author":"You","year":"2018","journal-title":"Am. J. Orthod. Dentofac."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1016\/j.ijom.2013.03.007","article-title":"Three-dimensional cone beam computed tomography definition of the anatomical subregions of the upper airway: A validation study","volume":"42","author":"Swennen","year":"2013","journal-title":"Int. J. Oral Max Surg."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/j.jcms.2012.03.003","article-title":"Changes in temporomandibular joint and ramus after sagittal split ramus osteotomy in mandibular prognathism patients with and without asymmetry","volume":"40","author":"Ueki","year":"2012","journal-title":"J. Cranio. Maxill Surg."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"S58","DOI":"10.1016\/j.ajodo.2009.01.025","article-title":"Evaluating the mandible with cone-beam computed tomography","volume":"137","author":"Ueki","year":"2010","journal-title":"Am. J. Orthod. Dentofac."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1067\/mod.2000.108781","article-title":"Stability of bilateral sagittal split ramus osteotomy: Rigid fixation versus transosseous wiring","volume":"118","author":"Berger","year":"2000","journal-title":"Am. J. Orthod. Dentofac."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1016\/j.joms.2019.03.020","article-title":"Three-Dimensional Evaluation of the Postsurgical Stability of Mandibular Setback with the Surgery-First Approach: Comparison between Patients With Symmetry and Asymmetry","volume":"77","author":"Sun","year":"2019","journal-title":"J. Oral Maxillofac. Surg."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1016\/j.jcms.2014.06.008","article-title":"Asymmetric mandibular prognathism: Outcome, stability and patient satisfaction after BSSRO surgery. A retrospective study","volume":"42","author":"Stenvik","year":"2014","journal-title":"J. Cranio-Maxillofac. Surg."},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Lin, H., Zhu, P., Lin, Q., Huang, X., Xu, Y., and Yang, X. (2016). Comprehensive Analysis of Mandibular Residual Asymmetry after Bilateral Sagittal Split Ramus Osteotomy Correction of Menton Point Deviation. PLoS ONE, 11.","DOI":"10.1371\/journal.pone.0161601"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.ijom.2021.08.008","article-title":"Three-dimensional condylar displacement and remodelling in patients with asymmetrical mandibular prognathism following bilateral sagittal split osteotomy","volume":"51","author":"Abotaleb","year":"2021","journal-title":"Int. J. Oral Maxillofac. Surg."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"209","DOI":"10.4041\/kjod.2013.43.5.209","article-title":"Comparison of the condyle-fossa relationship between skeletal class III malocclusion patients with and without asymmetry: A retrospective three-dimensional cone-beam computed tomograpy study","volume":"43","author":"Kim","year":"2013","journal-title":"Korean J. Orthod."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.tripleo.2005.04.007","article-title":"Is there any difference in the condylar position and angulation after asymmetric mandibular setback?","volume":"101","author":"Baek","year":"2006","journal-title":"Oral Surg. Oral Med. Oral Pathol. Oral Radio"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1093\/ejo\/cjp143","article-title":"Stress change on the temporomandibular joint in mandibular prognathism subjects with asymmetry after orthognathic surgery","volume":"32","author":"Ueki","year":"2010","journal-title":"Eur. J. Orthodont."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1007\/s10237-019-01227-0","article-title":"Effects on loads in temporomandibular joints for patients with mandibular asymmetry before and after orthognathic surgeries under the unilateral molar clenching","volume":"19","author":"Shu","year":"2020","journal-title":"Biomech. Model Mechan."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1016\/j.ijom.2016.08.015","article-title":"Comparison of the computed tomography values of the bone fragment gap after sagittal split ramus osteotomy in mandibular prognathism with and without asymmetry","volume":"45","author":"Moroi","year":"2016","journal-title":"Int. J. Oral Maxillofac. Surg."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.jcms.2015.11.019","article-title":"Change in mandibular body height at the site of a fixation plate in the advance (lengthening) and setback (shortening) sides after sagittal split ramus osteotomy","volume":"44","author":"Ueki","year":"2016","journal-title":"J. Cranio-Maxillofac. Surg."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"37","DOI":"10.4103\/1117-6806.199961","article-title":"Evaluation of Mandibular Condylar Changes in Patients following Orthognathic Surgery: A Retrospective Study","volume":"23","author":"Aneja","year":"2017","journal-title":"Niger. J. Surg."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1054\/bjom.2000.0303","article-title":"Evaluation of skeletal stability following surgical correction of mandibular prognathism","volume":"38","author":"Ayoub","year":"2000","journal-title":"Br. J. Oral Maxillofac. Surg."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/11\/23\/7131\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:30:43Z","timestamp":1760146243000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/11\/23\/7131"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,30]]},"references-count":26,"journal-issue":{"issue":"23","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["jcm11237131"],"URL":"https:\/\/doi.org\/10.3390\/jcm11237131","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,30]]}}}