{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T02:11:10Z","timestamp":1772244670315,"version":"3.50.1"},"reference-count":27,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2022,12,7]],"date-time":"2022-12-07T00:00:00Z","timestamp":1670371200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Singularity AG"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: This randomised crossover mannequin study aimed to compare the insertion time for the newly developed SingularityTM Air and the Ambu\u00ae AuraGainTM. The SingularityTM Air includes a bendable tube in order to allow optimal passform. Methods: Fifty anaesthetists with a minimum of 100 supraglottic airway device insertions were recruited and randomly assigned to start either with the SingularityTM Air or with the Ambu\u00ae AuraGainTM. Participants watched a tutorial video the day before the assessment and received a standardized introduction immediately before the assessment. The primary outcome was the time for successful insertion. Secondary parameters were the overall insertion success rate, the numbers of insertion attempts (maximum three), the glottic view through a flexible bronchoscope, and the success rate for gastric tube insertion. Results: Fifty participants were eventually recruited and randomly assigned to insert both devices according to the randomization. The insertion time was 24 s for SingularityTM Air as compared to 20 s for Ambu\u00ae AuraGainTM (p &lt; 0.001). Overall insertion rate was 92% for the SingularityTM Air as compared to 100% for the Ambu\u00ae AuraGainTM (p could not be derived as one variable is a constant). The primary insertion success rate was better for the Ambu\u00ae AuraGainTM than for the SingularityTM Air (94% versus 68%; p: 0.002, respectively). Conclusion: The time for successful insertion and the insertion success rate for the newly developed SingularityTM Air is inferior to that for the Ambu\u00ae AuraGainTM.<\/jats:p>","DOI":"10.3390\/jcm11247266","type":"journal-article","created":{"date-parts":[[2022,12,8]],"date-time":"2022-12-08T02:51:56Z","timestamp":1670467916000},"page":"7266","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Evaluation of the New SingularityTM Air versus Ambu\u00ae Aura GainTM: A Randomized, Crossover Mannequin Study"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4659-9114","authenticated-orcid":false,"given":"Lukas","family":"Gasteiger","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine, Medical University of Innsbruck, 6020 Innsbruck, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rouven","family":"Hornung","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine, Medical University of Innsbruck, 6020 Innsbruck, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Woyke","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine, Medical University of Innsbruck, 6020 Innsbruck, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabeth","family":"Hoerner","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine, Medical University of Innsbruck, 6020 Innsbruck, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabrina","family":"Neururer","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology, Tyrolean Federal Institute for Integrated Care, Tirol Kliniken GmbH, 6020 Innsbruck, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berthold","family":"Moser","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine, Medical University of Innsbruck, 6020 Innsbruck, Austria"},{"name":"Department of Anaesthesiology and Intensive Care Medicine, See-Spital Horgen, 8810 Horgen, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1097\/00000542-199307000-00021","article-title":"The laryngeal mask airway. Its uses in anesthesiology","volume":"79","author":"Pennant","year":"1993","journal-title":"Anesthesiology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1093\/bja\/84.5.650","article-title":"The LMA \u2018ProSeal\u2019\u2014A laryngeal mask with an oesophageal vent","volume":"84","author":"Brain","year":"2000","journal-title":"Br. J. Anaesth."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1097\/00000542-200007000-00019","article-title":"The ProSeal laryngeal mask airway: A randomized, crossover study with the standard laryngeal mask airway in paralyzed, anesthetized patients","volume":"93","author":"Brimacombe","year":"2000","journal-title":"Anesthesiology"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1097\/00000539-200010000-00046","article-title":"Does the ProSeal laryngeal mask airway prevent aspiration of regurgitated fluid?","volume":"91","author":"Keller","year":"2000","journal-title":"Anesth. Analg."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1111\/j.1365-2044.2010.06422.x","article-title":"Comparison of guided insertion of the LMA ProSeal vs the i-gel","volume":"65","author":"Gasteiger","year":"2010","journal-title":"Anaesthesia"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1111\/anae.12178","article-title":"A randomised, non-crossover study of the GuardianCPV Laryngeal Mask versus the LMA Supreme in paralysed, anaesthetised female patients","volume":"68","author":"Tiefenthaler","year":"2013","journal-title":"Anaesthesia"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1111\/j.1365-2044.2008.05682.x","article-title":"The laryngeal mask airway Supreme\u2014A single use laryngeal mask airway with an oesophageal vent. A randomised, cross-over study with the laryngeal mask airway ProSeal in paralysed, anaesthetised patients","volume":"64","author":"Eschertzhuber","year":"2009","journal-title":"Anaesthesia"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"684","DOI":"10.23736\/S0375-9393.17.12254-6","article-title":"A prospective, randomized trial of the Ambu AuraGain laryngeal mask versus the LMA(R) protector airway in paralyzed, anesthetized adult men","volume":"84","author":"Moser","year":"2018","journal-title":"Minerva Anestesiol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1007\/s00101-021-00914-x","article-title":"Guided vs. non-guided insertion of Ambu AuraGain in edentulous patients","volume":"70","author":"Gasteiger","year":"2021","journal-title":"Anaesthesist"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1097\/ALN.0b013e31827773b2","article-title":"Practice guidelines for management of the difficult airway: An updated report by the American Society of Anesthesiologists Task Force on Management of the Difficult Airway","volume":"118","author":"Apfelbaum","year":"2013","journal-title":"Anesthesiology"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1093\/bja\/aev371","article-title":"Difficult Airway Society 2015 guidelines for management of unanticipated difficult intubation in adults","volume":"115","author":"Frerk","year":"2015","journal-title":"Br. J. Anaesth."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1111\/pan.13785","article-title":"The design of the perfect pediatric supraglottic airway device","volume":"30","author":"Huang","year":"2020","journal-title":"Paediatr. Anaesth."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/s10877-020-00537-4","article-title":"The case for a 3rd generation supraglottic airway device facilitating direct vision placement","volume":"35","author":"Kumar","year":"2021","journal-title":"J. Clin. Monit. Comput."},{"key":"ref_14","unstructured":"(2022, November 12). Singularity_AG. Available online: https:\/\/singularityag.ch."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/s12630-018-1235-7","article-title":"Ambu(R) Aura Gain versus Ambu(R) Aura Once in children: A randomized, crossover study assessing oropharyngeal leak pressure and fibreoptic position","volume":"66","author":"Stogermuller","year":"2019","journal-title":"Can. J. Anaesth."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/aas.13242","article-title":"Fiberoptic intubation of severely obese patients through supraglottic airway: A prospective, randomized trial of the Ambu((R)) AuraGain laryngeal mask vs the i-gel airway","volume":"63","author":"Moser","year":"2019","journal-title":"Acta Anaesthesiol. Scand."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.23736\/S0375-9393.20.14422-5","article-title":"A randomized trial comparing the Ambu(R) Aura-i and the Ambu(R) Aura Gain laryngeal mask as conduit for tracheal intubation in children","volume":"86","author":"Gasteiger","year":"2020","journal-title":"Minerva Anestesiol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1093\/bja\/81.2.186","article-title":"Influence of cuff volume on oropharyngeal leak pressure and fibreoptic position with the laryngeal mask airway","volume":"81","author":"Keller","year":"1998","journal-title":"Br. J. Anaesth."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1007\/s12630-017-0936-7","article-title":"Flexible bronchoscopic intubation through the AuraGain laryngeal mask versus a slit Guedel tube: A non-inferiority randomized-controlled trial","volume":"64","author":"Moser","year":"2017","journal-title":"Can. J. Anaesth."},{"key":"ref_20","first-page":"457","article-title":"A proposed fiber-optic scoring system to standardize the assessment of laryngeal mask airway position","volume":"76","author":"Brimacombe","year":"1993","journal-title":"Anesth. Analg."},{"key":"ref_21","first-page":"e2020016","article-title":"Insertion of four different types of supraglottic airway devices by emergency nurses. A mannequin-based simulation study","volume":"91","author":"Liti","year":"2020","journal-title":"Acta Biomed."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"348","DOI":"10.4103\/joacp.JOACP_214_17","article-title":"Ambu AuraGain versus intubating laryngeal tube suction as a conduit for endotracheal intubation","volume":"35","author":"Bruceta","year":"2019","journal-title":"J. Anaesthesiol. Clin. Pharmacol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1111\/anae.12230","article-title":"Use of the air-Q intubating laryngeal airway for rapid-sequence intubation in infants with severe airway obstruction: A case series","volume":"68","author":"Jagannathan","year":"2013","journal-title":"Anaesthesia"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1111\/j.1460-9592.2010.03284.x","article-title":"Proposal for the management of the unexpected difficult pediatric airway","volume":"20","author":"Weiss","year":"2010","journal-title":"Paediatr. Anaesth."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1007\/s00431-018-3134-x","article-title":"Performance and skill retention of five supraglottic airway devices for the pediatric difficult airway in a manikin","volume":"177","author":"Kulnig","year":"2018","journal-title":"Eur. J. Pediatr."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.ajem.2015.03.006","article-title":"Performance of intubation with 4 different airway devices by unskilled rescuers: Manikin study","volume":"33","author":"Lee","year":"2015","journal-title":"Am. J. Emerg. Med."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.resuscitation.2015.05.001","article-title":"A radiographic comparison of human airway anatomy and airway manikins--Implications for manikin-based testing of artificial airways","volume":"92","author":"Schalk","year":"2015","journal-title":"Resuscitation"}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/11\/24\/7266\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:35:53Z","timestamp":1760146553000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/11\/24\/7266"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,7]]},"references-count":27,"journal-issue":{"issue":"24","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["jcm11247266"],"URL":"https:\/\/doi.org\/10.3390\/jcm11247266","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,7]]}}}