{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T21:12:00Z","timestamp":1769548320957,"version":"3.49.0"},"reference-count":20,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2022,12,26]],"date-time":"2022-12-26T00:00:00Z","timestamp":1672012800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100016224","name":"University Medical Center Maribor","doi-asserted-by":"publisher","award":["IRP-2020\/01-04"],"award-info":[{"award-number":["IRP-2020\/01-04"]}],"id":[{"id":"10.13039\/501100016224","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Aim: To compare the perinatal outcome and delivery intervals after the induction of labour with the Prostin vaginal tablet versus the Propess vaginal system in pregnant women with term-PROM. Design: One centre paralleled randomised controlled trial with a computer-generated table to allocate treatments. Setting: University Medical Centre in Slovenia. Participants: A total of 205 singleton healthy pregnant women with term-PROM. Intervention: Induction of labour with the Propess vaginal system (intervention group) versus Prostin tablets (control group). Main outcomes: The rate of failed inductions, complications in labour, time intervals between the PROM, induction, the beginning of the active phase, and delivery. Results: A total of 104 patients received Prostin, and 101 patients received Propess. Induction failure rates in the Prostin and the Propess groups were 8\/104 (7.7%) and 5\/101 (5.0%), respectively (p = 0.80). Delivery abnormalities were uncommon and comparable across the groups. The rates of caesarean sections in the Prostin and Propess groups were 4\/96 (4.2%) and 6\/96 (6.3%), respectively. The delivery intervals were comparable across the groups. Conclusions: In term-PROM pregnancies, the Propess vaginal system is a safe and effective option for inducing labour.<\/jats:p>","DOI":"10.3390\/jcm12010174","type":"journal-article","created":{"date-parts":[[2022,12,27]],"date-time":"2022-12-27T02:55:07Z","timestamp":1672109707000},"page":"174","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A Randomised Controlled Trial Comparing Induction of Labour with the Propess Vaginal System to the Prostin Vaginal Tablet in Premature Rupture of Membranes at Term"],"prefix":"10.3390","volume":"12","author":[{"given":"Veronika","family":"Anzeljc","sequence":"first","affiliation":[{"name":"Department of Perinatology, University Medical Centre Maribor, Ljubljanska 5, 2000 Maribor, Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faris","family":"Mujezinovi\u0107","sequence":"additional","affiliation":[{"name":"Department of Perinatology, University Medical Centre Maribor, Ljubljanska 5, 2000 Maribor, Slovenia"},{"name":"Faculty of Medicine, University of Maribor, Taborska 8, 2000 Maribor, Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1080\/01443615.2017.1329284","article-title":"Induction of labour in term premature rupture of membranes; oxytocin versus sublingual misoprostol a randomised clinical trial","volume":"38","author":"Pourali","year":"2018","journal-title":"J. Obstet. Gynaecol. J. Inst. Obstet. Gynaecol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1016\/j.jogc.2020.02.111","article-title":"Oral Misoprostol for Induction of Labour in Term PROM: A Systematic Review","volume":"42","author":"Padayachee","year":"2020","journal-title":"J. Obstet. Gynaecol. Can."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Committee on Practice Bulletins-Obstetrics (2018). ACOG Practice Bulletin No. 188: Prelabor Rupture of Membranes. Obstet. Gynecol., 131, e1\u2013e14.","DOI":"10.1097\/AOG.0000000000002663"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"151216","DOI":"10.1016\/j.semperi.2019.151216","article-title":"Cervical ripening: Why we do what we do","volume":"44","author":"Levine","year":"2020","journal-title":"Semin. 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Rev."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/12\/1\/174\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:51:12Z","timestamp":1760147472000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/12\/1\/174"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,26]]},"references-count":20,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,1]]}},"alternative-id":["jcm12010174"],"URL":"https:\/\/doi.org\/10.3390\/jcm12010174","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,26]]}}}