{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T18:22:53Z","timestamp":1783362173048,"version":"3.54.6"},"reference-count":35,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31670992"],"award-info":[{"award-number":["31670992"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["AQKY22-2-2"],"award-info":[{"award-number":["AQKY22-2-2"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Align Special Fund","award":["31670992"],"award-info":[{"award-number":["31670992"]}]},{"name":"Align Special Fund","award":["AQKY22-2-2"],"award-info":[{"award-number":["AQKY22-2-2"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Scissor bites have been reported in relatively few epidemiological studies because of their extremely low prevalence rate (below 1%). The etiology of scissor bites remains obscure, but its impact on growth and function should not be ignored. Methods: In this case report, a novel treatment that utilizes Invisalign aligners was performed on a 3-year-old child who presented with a bilateral posterior scissor bite and anterior crossbite, accompanied by multisite obstruction in the upper airway. The aligners functioned as occlusion pads to unlock the scissor bite relationship and combined with cross-traction to narrow the maxillary arch and enlarge the mandibular arch simultaneously. Results: The duration of orthodontic therapy was 28 weeks. A multidisciplinary consultation (orthodontics department, ENT department, and spinal surgery) was conducted and a stable result was achieved. A healthy occlusal relationship, improved dental esthetics and a better lateral profile were eventually obtained. Conclusions: Positive treatment outcomes rely on patients\u2019 good compliance in this case. In addition, we hope that clinicians will consider our situation in terms of alternative treatments and interprofessional experience.<\/jats:p>","DOI":"10.3390\/jcm12010333","type":"journal-article","created":{"date-parts":[[2023,1,2]],"date-time":"2023-01-02T03:00:59Z","timestamp":1672628459000},"page":"333","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Invisalign Treatment of a Three-Year-Old Child with Bilateral Posterior Scissor Bite and Multisite Upper Airway Obstruction: A Case Report"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5697-7302","authenticated-orcid":false,"given":"Yilin","family":"Xin","sequence":"first","affiliation":[{"name":"State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongling","family":"Zhou","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifan","family":"Zhao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lixing","family":"Zhao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.ajodo.2003.07.005","article-title":"Unilateral Brodie bite treated with distraction osteogenesis","volume":"125","author":"King","year":"2004","journal-title":"Am. J. Orthod. Dentofac. Orthop."},{"key":"ref_2","unstructured":"Kraus, B.S., and Riedel, R.A. (1962). The function matrix. Vistas of Orthodontics, Lea and Febiger."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/S2213-2600(17)30351-X","article-title":"Can we avoid development of a narrow upper airway and secondary abnormal breathing during sleep?","volume":"5","author":"Sullivan","year":"2017","journal-title":"Lancet Respir. Med."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1001\/archoto.2010.187","article-title":"Variation of patterns of malocclusion by site of pharyngeal obstruction in children","volume":"136","author":"Nunes","year":"2010","journal-title":"Arch. Otolaryngol. Head Neck Surg."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.ajodo.2014.10.028","article-title":"Influence of tonsillar grade on the dental arch measurements","volume":"147","author":"Diouf","year":"2015","journal-title":"Am. J. Orthod. Dentofac. Orthop."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.ijporl.2014.12.013","article-title":"Are distinct etiologies of upper airway obstruction in mouth-breathing children associated with different cephalometric patterns?","volume":"79","author":"Franco","year":"2015","journal-title":"Int. J. Pediatr. Otorhinolaryngol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"359","DOI":"10.2319\/073118-553.1","article-title":"Incidence of white spot lesions among patients treated with clear aligners and traditional braces","volume":"89","author":"Buschang","year":"2019","journal-title":"Angle Orthod."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s40510-019-0263-3","article-title":"Clear aligner treatment: Different perspectives between orthodontists and general dentists","volume":"20","author":"Perillo","year":"2019","journal-title":"Prog. Orthod."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1590\/S1678-77572012000300011","article-title":"Influence of lingual bracket position on microbial and periodontal parameters in vivo","volume":"20","author":"Sfondrini","year":"2012","journal-title":"J. Appl. Oral Sci."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.micpath.2018.08.011","article-title":"Comparison of oral microbiota in orthodontic patients and healthy individuals","volume":"123","author":"Sun","year":"2018","journal-title":"Microb. Pathog."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"401","DOI":"10.2214\/ajr.133.3.401","article-title":"Radiographic evaluation of adenoidal size in children: Adenoidal-nasopharyngeal ratio","volume":"133","author":"Fujioka","year":"1979","journal-title":"AJR Am. J. Roentgenol."},{"key":"ref_12","first-page":"43","article-title":"The adenoid-nasopharynx ratio: Its clinical value in children","volume":"31","author":"Zou","year":"1997","journal-title":"Chin. J. Radiol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"577","DOI":"10.2319\/031708-152.1","article-title":"Use of palatal miniscrew anchorage and lingual multi-bracket appliances to enhance efficiency of molar scissors-bite correction","volume":"79","author":"Tamamura","year":"2009","journal-title":"Angle Orthod."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.ajodo.2016.01.019","article-title":"Orthodontic uprighting of a horizontally impacted third molar and protraction of mandibular second and third molars into the missing first molar space for a patient with posterior crossbites","volume":"151","author":"Baik","year":"2017","journal-title":"Am. J. Orthod. Dentofac. Orthop."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S0889-5406(95)70084-6","article-title":"A case report of a Brodie bite","volume":"108","author":"Harper","year":"1995","journal-title":"Am. J. Orthod. Dentofac. Orthop."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/S0889-5406(03)00345-7","article-title":"Effectiveness of treatment for Class II malocclusion with the Herbst or twin-block appliances: A randomized, controlled trial","volume":"124","author":"Wright","year":"2003","journal-title":"Am. J. Orthod. Dentofac. Orthop."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/S0889-5406(03)00352-4","article-title":"Effectiveness of early orthodontic treatment with the Twin-block appliance: A multicenter, randomized, controlled trial. Part 1: Dental and skeletal effects","volume":"124","author":"Wright","year":"2003","journal-title":"Am. J. Orthod. Dentofac. Orthop."},{"key":"ref_18","first-page":"199","article-title":"Prevalence of malocclusion in children with upper airway obstruction","volume":"58","author":"Tinano","year":"2017","journal-title":"Rev. Port. Estomatol. Med. Dent. Cir. Maxilofac."},{"key":"ref_19","first-page":"147","article-title":"Oral respiration: Facial maldevelopment and corrective dentofacial orthopedics","volume":"50","author":"Subtelny","year":"1980","journal-title":"Angle Orthod."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/0002-9416(81)90379-1","article-title":"Primate experiments on oral respiration","volume":"79","author":"Harvold","year":"1981","journal-title":"Am. J. Orthod."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/S0011-8532(22)00626-7","article-title":"Habits affecting dental and maxillofacial growth and development","volume":"39","author":"Josell","year":"1995","journal-title":"Dent. Clin. N. Am."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"334","DOI":"10.14219\/jada.archive.1944.0071","article-title":"Frequency of allergy in orthodontic patients","volume":"31","author":"Straub","year":"1994","journal-title":"J. Am. Dent. Assoc."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/j.ijporl.2006.12.018","article-title":"An analysis of the incidence of adenoid hypertrophy in allergic children","volume":"71","author":"Modrzynski","year":"2007","journal-title":"Int. J. Pediatr. Otorhinolaryngol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1177\/1945892418765003","article-title":"Local Atopy in Childhood Adenotonsillar Hypertrophy","volume":"32","author":"Cho","year":"2018","journal-title":"Am. J. Rhinol. Allergy"},{"key":"ref_25","first-page":"45","article-title":"Correlation between allergy factors and maxillofacial malformation in children with tonsil and adenoid hypertrophy in denture replacement period","volume":"36","author":"Jin","year":"2022","journal-title":"J. Otolaryngol. Ophthalmol. Shandong Univ."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/j.ajodo.2016.10.027","article-title":"Relationships among nasal resistance, adenoids, tonsils, and tongue posture and maxillofacial form in Class II and Class III children","volume":"151","author":"Iwasaki","year":"2017","journal-title":"Am. J. Orthod. Dentofac. Orthop."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/S0165-5876(03)00095-8","article-title":"Muscular, functional and orthodontic changes in pre school children with enlarged adenoids and tonsils","volume":"67","author":"Valera","year":"2003","journal-title":"Int. J. Pediatr. Otorhinolaryngol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1093\/ejo\/cjs015","article-title":"The association of tongue posture with the dentoalveolar maxillary and mandibular morphology in Class III malocclusion: A controlled study","volume":"35","author":"Primozic","year":"2013","journal-title":"Eur. J. Orthod."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.ajodo.2008.12.028","article-title":"Three-dimensional ultrasound diagnostics of tongue posture in children with unilateral posterior crossbite","volume":"138","author":"Volk","year":"2010","journal-title":"Am. J. Orthod. Dentofac. Orthop."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1302\/1863-2548.13.190100","article-title":"Evaluation of a relationship between malocclusion and idiopathic scoliosis in children and adolescents","volume":"13","author":"Laskowska","year":"2019","journal-title":"J. Child. Orthop."},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Butera, A., Gallo, S., Pascadopoli, M., Taccardi, D., and Scribante, A. (2022). Home Oral Care of Periodontal Patients Using Antimicrobial Gel with Postbiotics, Lactoferrin, and Aloe Barbadensis Leaf Juice Powder vs. Conventional Chlorhexidine Gel: A Split-Mouth Randomized Clinical Trial. Antibiotics, 11.","DOI":"10.3390\/antibiotics11010118"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"42","DOI":"10.52010\/ijom.2014.40.1.4","article-title":"The Essential Role of the Com in the Management of Sleep-Disordered Breathing: A Literature Review and Discussion","volume":"40","author":"Frey","year":"2014","journal-title":"Int. J. Orofac. Myol."},{"key":"ref_33","first-page":"217","article-title":"Atypical swallowing: A review","volume":"63","author":"Maspero","year":"2014","journal-title":"Minerva Stomatol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"15","DOI":"10.52010\/ijom.1993.19.1.3","article-title":"Orthodontic changes in oral dyskinesia and malocclusion under the influence of myofunctional therapy","volume":"19","author":"Daglio","year":"1993","journal-title":"Int. J. Orofac. Myol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"66","DOI":"10.52010\/ijom.1995.21.1.10","article-title":"Integrating orthodontics and oral myofunctional therapy for patients with oral myofunctional disorders","volume":"21","author":"Takahashi","year":"1995","journal-title":"Int. J. Orofac. Myol."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/12\/1\/333\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T17:55:34Z","timestamp":1760118934000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/12\/1\/333"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,1]]},"references-count":35,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,1]]}},"alternative-id":["jcm12010333"],"URL":"https:\/\/doi.org\/10.3390\/jcm12010333","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,1]]}}}