{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T21:39:19Z","timestamp":1771623559739,"version":"3.50.1"},"reference-count":35,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,1,5]],"date-time":"2023-01-05T00:00:00Z","timestamp":1672876800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>The aim of this multicenter, national clinical audit is to evaluate the predictive factors and management of postoperative macular edema (ME) after retropupillary iris-claw intraocular lens (RICI) implantation and pars plana vitrectomy (PPV). Preoperative, surgical and postoperative data were collected. Number and type of intravitreal injections (IT) administered (anti-VEGF or dexamethasone implant), visual acuity (VA), intraocular pressure (IOP) and central retinal thickness (CRT) assessed by OCT were collected at 1, 3, 6 and 12 months. From 325 eyes (325 patients), 11.7% (38\/325) developed postoperative ME. Previous complicated cataract surgery with no capsular support was the only significant predictive factor for developing postoperative ME (OR 2.27, 95% CI 1.38\u20134.52, p = 0.02) after RICI implant. Mean time to ME development was 11.4 \u00b1 10.7 weeks, and mean CRT peaked at 3 months follow-up. Different treatment options were non-steroidal anti-inflammatory (NSAIDs) drops (31.6%, 12\/38), dexamethasone (DEX) implant (50%, 19\/38), anti-VEGF (7.9%, 3\/38) or combined IT (10.5%, 4\/38). Cumulative probability of ME resolution was higher in the group treated with IT than in the group treated with topical NSAIDs (85.2% vs. 58.3%, p = 0.9). Performing RICI implantation after complicated cataract surgery is a risk factor for the development of postoperative ME. DEX implants may be an effective treatment for postoperative ME in these cases.<\/jats:p>","DOI":"10.3390\/jcm12020436","type":"journal-article","created":{"date-parts":[[2023,1,5]],"date-time":"2023-01-05T04:51:31Z","timestamp":1672894291000},"page":"436","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Predictive Factors and Management of Macular Edema after Retropupillary Iris-Claw Intraocular Lens Implantation in Aphakia: National Multicenter Audit\u2014Report 2"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5469-3963","authenticated-orcid":false,"given":"Carolina","family":"Bernal-Morales","sequence":"first","affiliation":[{"name":"Institut Cl\u00ednic d\u2019Oftalmologia (ICOF), Hospital Cl\u00ednic, 08028 Barcelona, Spain"},{"name":"August Pi i Sunyer Biomedical Research Institute (IDIBAPS), 08036 Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel Javier","family":"Navarro-Angulo","sequence":"additional","affiliation":[{"name":"Institut Cl\u00ednic d\u2019Oftalmologia (ICOF), Hospital Cl\u00ednic, 08028 Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariano","family":"Rodriguez-Maqueda","sequence":"additional","affiliation":[{"name":"Hospital Universitario V\u00edrgen del Roc\u00edo, 41013 Sevilla, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8677-6859","authenticated-orcid":false,"given":"Daniel","family":"Velazquez-Villoria","sequence":"additional","affiliation":[{"name":"Hospital Povisa, 36211 Vigo, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan Manuel","family":"Cubero-Parra","sequence":"additional","affiliation":[{"name":"Hospital La Arruzafa, 14012 C\u00f3rdoba, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1185-375X","authenticated-orcid":false,"given":"Joaqu\u00edn","family":"Marticorena","sequence":"additional","affiliation":[{"name":"Instituto Oftalmol\u00f3gico La Esperanza, HM La Esperanza, 15705 Santiago de Compostela, Spain"},{"name":"Servicio de Oftalmolog\u00eda, Complejo Hospitalario Universitario, 15006 A Coru\u00f1a, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adri\u00e1n","family":"Hern\u00e1ndez-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Hospital Universitario Valme, 41014 Sevilla, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel","family":"Ruiz-Miguel","sequence":"additional","affiliation":[{"name":"Hospital Donostia, 20014 San Sebasti\u00e1n, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfredo","family":"Adan","sequence":"additional","affiliation":[{"name":"Institut Cl\u00ednic d\u2019Oftalmologia (ICOF), Hospital Cl\u00ednic, 08028 Barcelona, Spain"},{"name":"August Pi i Sunyer Biomedical Research Institute (IDIBAPS), 08036 Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Ruiz-Casas","sequence":"additional","affiliation":[{"name":"Servicio de Oftalmolog\u00eda, Hospital Ramon y Cajal, 28029 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2338-8143","authenticated-orcid":false,"given":"Javier","family":"Zarranz-Ventura","sequence":"additional","affiliation":[{"name":"Institut Cl\u00ednic d\u2019Oftalmologia (ICOF), Hospital Cl\u00ednic, 08028 Barcelona, Spain"},{"name":"August Pi i Sunyer Biomedical Research Institute (IDIBAPS), 08036 Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.ophtha.2016.10.024","article-title":"Late In-the-Bag Intraocular Lens Dislocation: A Randomized Clinical Trial Comparing Lens Repositioning and Lens Exchange","volume":"124","author":"Kristianslund","year":"2017","journal-title":"Ophthalmology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2016\/7013709","article-title":"Outcomes of Sutureless Iris-Claw Lens Implantation","volume":"2016","author":"Choragiewicz","year":"2016","journal-title":"J. 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