{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:45:36Z","timestamp":1760147136930,"version":"build-2065373602"},"reference-count":71,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,1,9]],"date-time":"2023-01-09T00:00:00Z","timestamp":1673222400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Medical University of Lodz, Poland"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Crohn\u2019s disease (CD) is a subtype of chronic inflammatory bowel diseases (IBD) with characteristic skip lesions and transmural inflammation that may affect the entire gastrointestinal tract from the mouth to the anus. Persistent pain is one of the main symptoms of CD. This pain has multifactorial pathogenesis, but most often arises from intestinal inflammation itself, as well as from gut distention or partial intestinal obstruction. Some current evidence also suggests sensitization of sensory pathways, as well as modulation of those signals by the central nervous system, which highlights the impact of biopsychosocial factors. To date, most studies have focused only on the pain located in the abdomen, while pelvic pain has rarely been explored, despite it being a common symptom. The aim of this study is to provide an abbreviated summary of the current state of knowledge on the origins and treatment of pelvic pain in CD.<\/jats:p>","DOI":"10.3390\/jcm12020526","type":"journal-article","created":{"date-parts":[[2023,1,9]],"date-time":"2023-01-09T05:57:14Z","timestamp":1673243834000},"page":"526","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Management of Pelvic Pain in Patients with Crohn\u2019s Disease\u2014Current Overview"],"prefix":"10.3390","volume":"12","author":[{"given":"Jakub","family":"W\u0142odarczyk","sequence":"first","affiliation":[{"name":"Department of General and Oncological, Medical University of Lodz, Pomorska 251, 90-213 Lodz, Poland"},{"name":"Department of Biochemistry, Medical University of Lodz, Mazowiecka 6\/8, 92-215 Lodz, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacek","family":"Burzy\u0144ski","sequence":"additional","affiliation":[{"name":"Department of General and Oncological, Medical University of Lodz, Pomorska 251, 90-213 Lodz, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bart\u0142omiej","family":"Czerwi\u0144ski","sequence":"additional","affiliation":[{"name":"Department of General and Oncological, Medical University of Lodz, Pomorska 251, 90-213 Lodz, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mateusz","family":"Prusisz","sequence":"additional","affiliation":[{"name":"Department of General and Oncological, Medical University of Lodz, Pomorska 251, 90-213 Lodz, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7706-2080","authenticated-orcid":false,"given":"Katarzyna","family":"Soca\u0142a","sequence":"additional","affiliation":[{"name":"Department of Animal Physiology and Pharmacology, Institute of Biological Sciences, Maria Curie-Sk\u0142odowska University, Akademicka 19, 20-033 Lublin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4359-3953","authenticated-orcid":false,"given":"Ewa","family":"Poleszak","sequence":"additional","affiliation":[{"name":"Chair and Department of Applied and Social Pharmacy, Medical University of Lublin, Chod\u017aki 1, 20-093 Lublin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8443-4417","authenticated-orcid":false,"given":"Jakub","family":"Fichna","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Medical University of Lodz, Mazowiecka 6\/8, 92-215 Lodz, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kasper","family":"Mary\u0144czak","sequence":"additional","affiliation":[{"name":"Department of General and Oncological, Medical University of Lodz, Pomorska 251, 90-213 Lodz, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9118-4623","authenticated-orcid":false,"given":"Marcin","family":"W\u0142odarczyk","sequence":"additional","affiliation":[{"name":"Department of General and Oncological, Medical University of Lodz, Pomorska 251, 90-213 Lodz, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0141ukasz","family":"Dziki","sequence":"additional","affiliation":[{"name":"Department of General and Oncological, Medical University of Lodz, Pomorska 251, 90-213 Lodz, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,9]]},"reference":[{"key":"ref_1","first-page":"S53","article-title":"Apoptosis Markers of Circulating Leukocytes Are Associated with the Clinical Course of Inflammatory Bowel Disease","volume":"11","author":"Kadijani","year":"2018","journal-title":"Gastroenterol. 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