{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T15:38:03Z","timestamp":1783957083827,"version":"3.55.0"},"reference-count":31,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2023,2,16]],"date-time":"2023-02-16T00:00:00Z","timestamp":1676505600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Key R&amp;D Program of China","award":["2017YFC1308000"],"award-info":[{"award-number":["2017YFC1308000"]}]},{"name":"National Key R&amp;D Program of China","award":["2018-2-2-66"],"award-info":[{"award-number":["2018-2-2-66"]}]},{"name":"National Key R&amp;D Program of China","award":["PXM2017_014226_000037"],"award-info":[{"award-number":["PXM2017_014226_000037"]}]},{"name":"Capital Health Research and Development of Special","award":["2017YFC1308000"],"award-info":[{"award-number":["2017YFC1308000"]}]},{"name":"Capital Health Research and Development of Special","award":["2018-2-2-66"],"award-info":[{"award-number":["2018-2-2-66"]}]},{"name":"Capital Health Research and Development of Special","award":["PXM2017_014226_000037"],"award-info":[{"award-number":["PXM2017_014226_000037"]}]},{"name":"Beijing Lab for Cardiovascular Precision Medicine","award":["2017YFC1308000"],"award-info":[{"award-number":["2017YFC1308000"]}]},{"name":"Beijing Lab for Cardiovascular Precision Medicine","award":["2018-2-2-66"],"award-info":[{"award-number":["2018-2-2-66"]}]},{"name":"Beijing Lab for Cardiovascular Precision Medicine","award":["PXM2017_014226_000037"],"award-info":[{"award-number":["PXM2017_014226_000037"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>There are relatively few articles on the relationship between serum albumin and acute kidney injury (AKI). Therefore, the objective of this research was to study the relationship between serum albumin and AKI in patients who were undergoing surgery for acute type A aortic dissection. Methods: We retrospectively collected data from 624 patients attending a Chinese hospital between January 2015 and June 2017. The target independent variable was serum albumin measured before surgery after hospital admission, and the dependent variable was AKI, defined in accordance with the Kidney Disease Improving Global Outcomes (KDIGO) criteria. Results: The mean age of these 624 selected patients was 48.5 \u00b1 11.1 years, and almost 73.7% were male. A nonlinear association was detected between serum albumin and AKI; the turning point was 32 g\/L. The risk of AKI decreased gradually as the serum albumin level increased up to 32 g\/L (adjusted OR = 0.87; 95% CI 0.82\u20130.92; p &lt; 0.001). When the serum albumin level exceeded 32 g\/L, the level of serum albumin was not associated with the risk of AKI (OR = 1.01, 95% CI 0.94\u20131.08; p = 0.769). Conclusions: The findings suggest that preoperative serum albumin below 32 g\/L was an independent risk factor for AKI in patients undergoing surgery for acute type A aortic dissection. Trial registration: A retrospective cohort study.<\/jats:p>","DOI":"10.3390\/jcm12041581","type":"journal-article","created":{"date-parts":[[2023,2,17]],"date-time":"2023-02-17T01:32:56Z","timestamp":1676597576000},"page":"1581","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Influence of Preoperative Serum Albumin on Acute Kidney Injury after Aortic Surgery for Acute Type A Aortic Dissection: A Retrospective Cohort Study"],"prefix":"10.3390","volume":"12","author":[{"given":"Shijun","family":"Xu","sequence":"first","affiliation":[{"name":"Beijing Aortic Disease Center, Department of Cardiac Surgery, Beijing Anzhen Hospital, Beijing 100029, China"},{"name":"Beijing Laboratory for Cardiovascular Precision Medicine, Beijing Institute of Heart Lung and Blood Vessel Diseases, Capital Medical University, Beijing 100029, China"},{"name":"Beijing Engineering Research Center of Vascular Prostheses, No.2 Anzhen Street, Beijing 100029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6629-8944","authenticated-orcid":false,"given":"Zining","family":"Wu","sequence":"additional","affiliation":[{"name":"Beijing Aortic Disease Center, Department of Cardiac Surgery, Beijing Anzhen Hospital, Beijing 100029, China"},{"name":"Beijing Laboratory for Cardiovascular Precision Medicine, Beijing Institute of Heart Lung and Blood Vessel Diseases, Capital Medical University, Beijing 100029, China"},{"name":"Beijing Engineering Research Center of Vascular Prostheses, No.2 Anzhen Street, Beijing 100029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongmin","family":"Liu","sequence":"additional","affiliation":[{"name":"Beijing Aortic Disease Center, Department of Cardiac Surgery, Beijing Anzhen Hospital, Beijing 100029, China"},{"name":"Beijing Laboratory for Cardiovascular Precision Medicine, Beijing Institute of Heart Lung and Blood Vessel Diseases, Capital Medical University, Beijing 100029, China"},{"name":"Beijing Engineering Research Center of Vascular Prostheses, No.2 Anzhen Street, Beijing 100029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junming","family":"Zhu","sequence":"additional","affiliation":[{"name":"Beijing Aortic Disease Center, Department of Cardiac Surgery, Beijing Anzhen Hospital, Beijing 100029, China"},{"name":"Beijing Laboratory for Cardiovascular Precision Medicine, Beijing Institute of Heart Lung and Blood Vessel Diseases, Capital Medical University, Beijing 100029, China"},{"name":"Beijing Engineering Research Center of Vascular Prostheses, No.2 Anzhen Street, Beijing 100029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Gong","sequence":"additional","affiliation":[{"name":"Beijing Aortic Disease Center, Department of Cardiac Surgery, Beijing Anzhen Hospital, Beijing 100029, China"},{"name":"Beijing Laboratory for Cardiovascular Precision Medicine, Beijing Institute of Heart Lung and Blood Vessel Diseases, Capital Medical University, Beijing 100029, China"},{"name":"Beijing Engineering Research Center of Vascular Prostheses, No.2 Anzhen Street, Beijing 100029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lizhong","family":"Sun","sequence":"additional","affiliation":[{"name":"Beijing Aortic Disease Center, Department of Cardiac Surgery, Beijing Anzhen Hospital, Beijing 100029, China"},{"name":"Beijing Laboratory for Cardiovascular Precision Medicine, Beijing Institute of Heart Lung and Blood Vessel Diseases, Capital Medical University, Beijing 100029, China"},{"name":"Beijing Engineering Research Center of Vascular Prostheses, No.2 Anzhen Street, Beijing 100029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Ran","sequence":"additional","affiliation":[{"name":"Beijing Aortic Disease Center, Department of Cardiac Surgery, Beijing Anzhen Hospital, Beijing 100029, China"},{"name":"Beijing Laboratory for Cardiovascular Precision Medicine, Beijing Institute of Heart Lung and Blood Vessel Diseases, Capital Medical University, Beijing 100029, China"},{"name":"Beijing Engineering Research Center of Vascular Prostheses, No.2 Anzhen Street, Beijing 100029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongjia","family":"Zhang","sequence":"additional","affiliation":[{"name":"Beijing Aortic Disease Center, Department of Cardiac Surgery, Beijing Anzhen Hospital, Beijing 100029, China"},{"name":"Beijing Laboratory for Cardiovascular Precision Medicine, Beijing Institute of Heart Lung and Blood Vessel Diseases, Capital Medical University, Beijing 100029, China"},{"name":"Beijing Engineering Research Center of Vascular Prostheses, No.2 Anzhen Street, Beijing 100029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,2,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"I237","DOI":"10.1161\/01.CIR.0000138219.67028.2a","article-title":"Differences in Clinical Presentation, Management, and Outcomes of Acute Type A Aortic Dissection in Patients With and Without Previous Cardiac Surgery","volume":"110","author":"Collins","year":"2004","journal-title":"Circulation"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0003-4975(00)01824-5","article-title":"Emergency operation for acute type A aortic dissection: Neurologic complications and early mortality","volume":"71","author":"Sinatra","year":"2001","journal-title":"Ann. 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Anesth."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/12\/4\/1581\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T18:38:20Z","timestamp":1760121500000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/12\/4\/1581"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,16]]},"references-count":31,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2023,2]]}},"alternative-id":["jcm12041581"],"URL":"https:\/\/doi.org\/10.3390\/jcm12041581","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,16]]}}}