{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T17:11:50Z","timestamp":1789060310460,"version":"build-2803163510"},"reference-count":52,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2023,2,17]],"date-time":"2023-02-17T00:00:00Z","timestamp":1676592000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>The objectives of this study were to characterize dietary fiber (DF) intake in patients with ankylosing spondylitis (AS), to assess whether DF intake affects disease activity in AS, and to investigate the effect of DF intake on disease activity in AS in the context of functional bowel disease (FBD) symptoms. We recruited 165 patients with AS and divided them into two groups according to whether they had a high DF intake &gt; 25 g\/d to investigate the characteristics of people with high DF intake. Some 72 of the 165 AS patients (43%) met the criteria for high DF intake, which was more common in patients with negative FBD symptoms (68%). Data analysis revealed that DF intake was negatively associated with AS disease activity and did not differ statistically significantly from FBD symptoms. Multivariate adjusted models were used to explore the effect of DF intake on AS disease activity. ASDAS-CRP and BASDAI were stable and negatively correlated across models in both groups with and without FBD symptoms. Thus, DF intake positively affected disease activity in patients with AS. ASDAS-CRP and BASDAI were negatively correlated with DF intake.<\/jats:p>","DOI":"10.3390\/jcm12041621","type":"journal-article","created":{"date-parts":[[2023,2,20]],"date-time":"2023-02-20T02:02:09Z","timestamp":1676858529000},"page":"1621","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Dietary Fiber Intake Influences Changes in Ankylosing Spondylitis Disease Status"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2844-2527","authenticated-orcid":false,"given":"Chuan","family":"Song","sequence":"first","affiliation":[{"name":"Department of Rheumatology and Immunology, The First Medical Center, Chinese PLA General Hospital, Beijing 100039, China"},{"name":"Medical School of Chinese PLA, Beijing 100039, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, The First Medical Center, Chinese PLA General Hospital, Beijing 100039, China"},{"name":"Department of Gastroenterology, Air Force Medical Center, Air Force Medical University, Beijing 100142, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4753-191X","authenticated-orcid":false,"given":"Xiaojian","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, The First Medical Center, Chinese PLA General Hospital, Beijing 100039, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiwen","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, The First Medical Center, Chinese PLA General Hospital, Beijing 100039, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lidong","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, The First Medical Center, Chinese PLA General Hospital, Beijing 100039, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingkang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, The First Medical Center, Chinese PLA General Hospital, Beijing 100039, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaxin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, The First Medical Center, Chinese PLA General Hospital, Beijing 100039, China"},{"name":"Medical School of Chinese PLA, Beijing 100039, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simin","family":"Liao","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, The First Medical Center, Chinese PLA General Hospital, Beijing 100039, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yishu","family":"Yan","sequence":"additional","affiliation":[{"name":"Medical School of Chinese PLA, Beijing 100039, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, The First Medical Center, Chinese PLA General Hospital, Beijing 100039, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2319-873X","authenticated-orcid":false,"given":"Feng","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, The First Medical Center, Chinese PLA General Hospital, Beijing 100039, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,2,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2563","DOI":"10.1056\/NEJMra1406182","article-title":"Ankylosing Spondylitis and Axial Spondyloarthritis","volume":"374","author":"Taurog","year":"2016","journal-title":"N. 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