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The development of atherosclerosis is the most common culprit behind ailments such as myocardial infarction, stroke, and peripheral vascular disease. Consequently, it imposes a significant burden on life expectancy, quality of life, morbidity, and societal costs. Both increased cholesterol levels and the activation of the inflammatory cascade are known as cardiovascular risk facts. Their relative weight is in the spotlight of curent biomedical research. Newly published data shed light on the role of inflammation in determining cardiovascular risk irrespective of cholesterol levels and cholesterol-lowering therapies.<\/jats:p>","DOI":"10.3390\/jcm12072519","type":"journal-article","created":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T05:34:30Z","timestamp":1679895270000},"page":"2519","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Inflammation Beats Cholesterol: A Comment on the Unequivocal Driver of Cardiovascular Disease Risk"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3060-318X","authenticated-orcid":false,"given":"Mauro","family":"Vaccarezza","sequence":"first","affiliation":[{"name":"Curtin Medical School, Faculty of Health Sciences, Curtin University, Bentley, Perth, WA 6102, Australia"},{"name":"Curtin Health Innovation Research Institute, Faculty of Health Sciences, Curtin University, Bentley, Perth, WA 6102, Australia"},{"name":"Department of Environmental and Prevention Sciences, University of Ferrara, 44121 Ferrara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco Maria","family":"Galassi","sequence":"additional","affiliation":[{"name":"Department of Anthropology, Faculty of Biology and Environmental Protection, University of Lodz, 90-237 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,3,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1161\/CIRCRESAHA.117.311427","article-title":"A Unique Case of Stroke and Upper Limb Paralysis in a Mid-18th Century Natural Mummy","volume":"121","author":"Galassi","year":"2017","journal-title":"Circ. 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