{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T04:00:59Z","timestamp":1792555259419,"version":"4.5.0"},"reference-count":30,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T00:00:00Z","timestamp":1680480000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>This study investigated the impact of partial splenic embolization (PSE) on portal hypertensive gastropathy (PHG). We retrospectively analyzed endoscopic findings and the portal venous system of 31 cirrhotic patients with PHG. The improved group was defined as the amelioration of PHG findings using the McCormack classification. Child\u2013Pugh scores of the improved group (18 of 31 patients) were significantly lower compared with those of the non-improved group (p = 0.018). The changes in the diameters of the portal trunk and those of the spleno-portal junction and spleen hilum in the splenic vein of the improved group were significantly larger than those of the non-improved group (p = 0.007, p = 0.025, and p = 0.003, respectively). The changes in the diameters of the portal vein and splenic hilum of the splenic vein showed significant correlations with Child\u2013Pugh score (r = 0.386, p = 0.039; r = 0.510, p = 0.004). In a multivariate analysis of baseline factors related to the improved group, Child\u2013Pugh grade A was significantly associated with the improvement of PHG (odds ratio 6.875, p = 0.033). PSE could be useful for PHG, especially in patients with Child\u2013Pugh grade A, at least in the short term.<\/jats:p>","DOI":"10.3390\/jcm12072662","type":"journal-article","created":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T02:10:13Z","timestamp":1680487813000},"page":"2662","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The Impact of Partial Splenic Embolization on Portal Hypertensive Gastropathy in Cirrhotic Patients with Portal Hypertension"],"prefix":"10.3390","volume":"12","author":[{"given":"Michio","family":"Saeki","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Juntendo University Nerima Hospital, Tokyo 177-8521, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hironao","family":"Okubo","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Juntendo University Nerima Hospital, Tokyo 177-8521, Japan"},{"name":"Department of Gastroenterology, Graduate School of Medicine, Juntendo University, Tokyo 113-8421, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5036-4545","authenticated-orcid":false,"given":"Yusuke","family":"Takasaki","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Juntendo University Nerima Hospital, Tokyo 177-8521, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eisuke","family":"Nakadera","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Juntendo University Nerima Hospital, Tokyo 177-8521, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuka","family":"Fukuo","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Juntendo University Nerima Hospital, Tokyo 177-8521, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroo","family":"Fukada","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Graduate School of Medicine, Juntendo University, Tokyo 113-8421, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuta","family":"Hotchi","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Juntendo University Nerima Hospital, Tokyo 177-8521, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3371-3157","authenticated-orcid":false,"given":"Hitoshi","family":"Maruyama","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Graduate School of Medicine, Juntendo University, Tokyo 113-8421, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigehiro","family":"Kokubu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Juntendo University Nerima Hospital, Tokyo 177-8521, Japan"},{"name":"Department of Gastroenterology, Shin-Yurigaoka General Hospital, Kawasaki 215-0026, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuichiro","family":"Shiina","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Graduate School of Medicine, Juntendo University, Tokyo 113-8421, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5979-4384","authenticated-orcid":false,"given":"Akihito","family":"Nagahara","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Graduate School of Medicine, Juntendo University, Tokyo 113-8421, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenichi","family":"Ikejima","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Graduate School of Medicine, Juntendo University, Tokyo 113-8421, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1136\/gut.26.11.1226","article-title":"Gastric lesions in portal hypertension: Inflammatory gastritis or congestive gastropathy?","volume":"26","author":"McCormack","year":"1985","journal-title":"Gut"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1002\/hep.1840180323","article-title":"Involvement of nitric oxide and prostaglandins in gastric mucosal hyperemia of portal-hypertensive anesthetized rats","volume":"18","author":"Casadevall","year":"1993","journal-title":"Hepatology"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00508-019-01593-w","article-title":"Portal hypertensive gastropathy is associated with iron deficiency anemia","volume":"132","author":"Simbrunner","year":"2020","journal-title":"Wien Klin. 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