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Taiwan","award":["DMR-HHC-109-12"],"award-info":[{"award-number":["DMR-HHC-109-12"]}]},{"name":"China Medical University Hospital, Taichung, Taiwan","award":["DMR-HHC-110-10"],"award-info":[{"award-number":["DMR-HHC-110-10"]}]},{"name":"China Medical University Hospital, Taichung, Taiwan","award":["DMR-HHC-111-8"],"award-info":[{"award-number":["DMR-HHC-111-8"]}]},{"name":"China Medical University Hospital, Taichung, Taiwan","award":["CMUH-C1110812016-11"],"award-info":[{"award-number":["CMUH-C1110812016-11"]}]},{"name":"National Science and Technology Council, Taiwan","award":["NSTC 111-2314-B-039-041-MY3"],"award-info":[{"award-number":["NSTC 111-2314-B-039-041-MY3"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>The efficacy of current pharmaceutical treatments for fibromyalgia are limited. Vitamin D has shown promise in relieving pain. However, there is a lack of comprehensive analysis of psychological outcomes with vitamin D supplementation in fibromyalgia. This study aimed to investigate the impact of vitamin D supplementation on psychological outcomes and quality of life in fibromyalgia patients, given the unmet clinical need for effective treatment options. A meta-analysis of randomized controlled trials comparing vitamin D to placebo and prospective studies examining changes before and after vitamin D supplementation for patients with fibromyalgia was conducted to evaluate the effects of vitamin D on psychological outcomes, quality of life, and pain scores in patients with fibromyalgia. Databases were searched for relevant articles published from earliest available date to October 31, 2022. (PROSPERO number, CRD42022369889). We included 8 trials with a total of 694 participants and found that vitamin D supplementation had significant positive effects on physical function (standard mean differences (SMD) = 0.44, 95% CI = [0.10, 0.77 ]), role limitations due to emotional health (SMD = 0.57, 95% CI = [0.32, 0.82]), social function (SMD = 0.50, 95% CI = [0.08, 0.93]), and general health (SMD = 0.36, 95% CI = [0.11, 0.61]). Improvement of the Fibromyalgia Impact Questionnaire (FIQ) scores was noted (SMD = \u22120.414, 95% CI = [\u22120.808, \u22120.021]), but not on the Visual Analog Scale (VAS) (SMD = \u22120.15, 95% CI = [\u22120.771, 0.471]) and the Beck\u2019s Depression Inventory (BDI) scores (SMD = \u22120.456, 95% CI = [\u22121.27, 0.30]). In conclusion, vitamin D supplementation might be an alternative option for improvement of psychological outcomes and quality of life in patients with fibromyalgia.<\/jats:p>","DOI":"10.3390\/jcm12072750","type":"journal-article","created":{"date-parts":[[2023,4,7]],"date-time":"2023-04-07T04:04:16Z","timestamp":1680840256000},"page":"2750","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Psychological Outcomes and Quality of Life of Fibromyalgia Patients with Vitamin D Supplementation\u2014A Meta-Analysis"],"prefix":"10.3390","volume":"12","author":[{"given":"Chia-Chun","family":"Yang","sequence":"first","affiliation":[{"name":"Department of General Psychiatry, Taoyuan Psychiatric Center, Taoyuan 330, Taiwan"},{"name":"Mind-Body Interface Laboratory (MBI-Lab), Department of Psychiatry, China Medical University Hospital, Taichung 404, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9932-7801","authenticated-orcid":false,"given":"Sheng-Ta","family":"Tsai","sequence":"additional","affiliation":[{"name":"School of Medicine, China Medical University, Taichung 404, Taiwan"},{"name":"Department of Neurology, China Medical University Hospital, Taichung 404, Taiwan"},{"name":"Neuroscience and Brain Disease Center, China Medical University, Taichung 404, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5752-082X","authenticated-orcid":false,"given":"Berne","family":"Ting","sequence":"additional","affiliation":[{"name":"Mind-Body Interface Laboratory (MBI-Lab), Department of Psychiatry, China Medical University Hospital, Taichung 404, Taiwan"},{"name":"Ph.D. Program for Aging, College of Medicine, China Medical University, Taichung 404, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-Chih","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, China Medical University Hsinchu Hospital, China Medical University, Hsinchu 302, Taiwan"},{"name":"Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei 106, Taiwan"},{"name":"Research Center of Big Data and Meta-Analysis, Wan Fang Hospital, Taipei Medical University, Taipei 110, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5371-7847","authenticated-orcid":false,"given":"Chin-Kun","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Chung Shan Medical University, Taichung 402, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5582-0928","authenticated-orcid":false,"given":"Jane","family":"Chang","sequence":"additional","affiliation":[{"name":"Mind-Body Interface Laboratory (MBI-Lab), Department of Psychiatry, China Medical University Hospital, Taichung 404, Taiwan"},{"name":"School of Medicine, China Medical University, Taichung 404, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4501-2502","authenticated-orcid":false,"given":"Kuan-Pin","family":"Su","sequence":"additional","affiliation":[{"name":"Mind-Body Interface Laboratory (MBI-Lab), Department of Psychiatry, China Medical University Hospital, Taichung 404, Taiwan"},{"name":"Graduate Institute of Biomedical Sciences, China Medical University, Taichung 404, Taiwan"},{"name":"An-Nan Hospital, China Medical University, Tainan 709, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"495","DOI":"10.3109\/07853890.2011.595734","article-title":"Fibromyalgia diagnosis and diagnostic criteria","volume":"43","author":"Wolfe","year":"2011","journal-title":"Ann. Med."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.rbr.2016.10.004","article-title":"Prevalence of fibromyalgia: Literature review update","volume":"57","author":"Marques","year":"2017","journal-title":"Rev. Bras. Reumatol. Engl. Ed."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1002\/acr.20140","article-title":"The American College of Rheumatology Preliminary Diagnostic Criteria for Fibromyalgia and Measurement of Symptom Severity","volume":"62","author":"Wolfe","year":"2010","journal-title":"Arthritis Care Res."},{"key":"ref_4","first-page":"R54","article-title":"Treating patients with fibromyalgia in primary care settings under routine medical practice: A claim database cost and burden of illness study","volume":"11","author":"Rejas","year":"2009","journal-title":"Thromb. Haemost."},{"key":"ref_5","first-page":"S39","article-title":"Resource utilisation and health care costs in patients diagnosed with fibromyalgia in Spain","volume":"27","author":"Rivera","year":"2009","journal-title":"Clin. Exp. Rheumatol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1038\/s41584-020-00506-w","article-title":"Fibromyalgia: An update on clinical characteristics, aetiopathogenesis and treatment","volume":"16","author":"Giorgi","year":"2020","journal-title":"Nat. Rev. Rheumatol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"2238","DOI":"10.3899\/jrheum.110026","article-title":"The Longitudinal Outcome of Fibromyalgia: A Study of 1555 Patients","volume":"38","author":"Walitt","year":"2011","journal-title":"J. Rheumatol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.biopsych.2014.01.008","article-title":"Omega-3 Fatty Acids in the Prevention of Interferon-Alpha-Induced Depression: Results from a Randomized, Controlled Trial","volume":"76","author":"Su","year":"2014","journal-title":"Biol. Psychiatry"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.biopsych.2010.03.018","article-title":"A Meta-Analytic Review of Polyunsaturated Fatty Acid Compositions in Patients with Depression","volume":"68","author":"Lin","year":"2010","journal-title":"Biol. Psychiatry"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Kv\u00e6l, L.A.H., L\u00f8chting, I., and Molin, M. (2021). Use of Dietary Supplements and Perceived Knowledge among Adults Living with Fibromyalgia in Norway: A Cross-Sectional Study. Nutrients, 14.","DOI":"10.3390\/nu14010005"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.biopha.2018.04.056","article-title":"Fibromyalgia and nutrition: Therapeutic possibilities?","volume":"103","author":"Dadar","year":"2018","journal-title":"Biomed. Pharmacother."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1100\/tsw.2006.25","article-title":"Vitamin D as a Neuroactive Substance: Review","volume":"6","author":"Kiraly","year":"2006","journal-title":"Sci. World J."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.bbi.2019.04.006","article-title":"Altered gut microbiota and endocannabinoid system tone in vitamin D deficiency-mediated chronic pain","volume":"85","author":"Guida","year":"2019","journal-title":"Brain Behav. Immun."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1017\/S1368980018000551","article-title":"The association between vitamin D concentration and pain: A systematic review and meta-analysis","volume":"21","author":"Wu","year":"2018","journal-title":"Public Heal. Nutr."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1136\/ard.2009.116053","article-title":"Musculoskeletal pain is associated with very low levels of vitamin D in men: Results from the European Male Ageing Study","volume":"69","author":"McBeth","year":"2010","journal-title":"Ann. Rheum. Dis."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"R23","DOI":"10.1530\/JOE-16-0514","article-title":"The interfaces between vitamin D, sleep and pain","volume":"234","author":"Hirotsu","year":"2017","journal-title":"J. Endocrinol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1002\/da.23025","article-title":"The effect of vitamin D supplement on negative emotions: A systematic review and meta-analysis","volume":"37","author":"Cheng","year":"2020","journal-title":"Depress. Anxiety"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"250","DOI":"10.3344\/kjp.2017.30.4.250","article-title":"Vitamin D and fibromyalgia: A meta-analysis","volume":"30","author":"Makrani","year":"2017","journal-title":"Korean J. Pain"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"820","DOI":"10.3389\/fimmu.2020.00820","article-title":"Vitamin D and Its Potential Interplay With Pain Signaling Pathways","volume":"11","author":"Habib","year":"2020","journal-title":"Front. Immunol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1002\/brb3.17","article-title":"White matter maturation of normal human fetal brain. An in vivo diffusion tensor tractography study","volume":"1","author":"Zanin","year":"2011","journal-title":"Brain Behav."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"e01760","DOI":"10.1002\/brb3.1760","article-title":"Vitamin D supplementation improves anxiety but not depression symptoms in patients with vitamin D deficiency","volume":"10","author":"Zhu","year":"2020","journal-title":"Brain Behav."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"109323","DOI":"10.1016\/j.mehy.2019.109323","article-title":"Patient characteristics and analgesic efficacy of antiviral therapy in postherpetic neuralgia","volume":"131","author":"Lin","year":"2019","journal-title":"Med. Hypotheses"},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Hausmann, J., Kubesch, A., Amiri, M., Filmann, N., and Blumenstein, I. (2019). Vitamin D Deficiency is Associated with Increased Disease Activity in Patients with Inflammatory Bowel Disease. J. Clin. Med., 8.","DOI":"10.3390\/jcm8091319"},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Aksan, A., Tugal, D., Hein, N., Boettger, K., Caicedo-Zea, Y., Diehl, I., Schumann, C., Armbruster, F.-P., and Stein, J. (2020). Measuring Vitamin D Status in Chronic Inflammatory Disorders: How does Chronic Inflammation Affect the Reliability of Vitamin D Metabolites in Patients with IBD?. J. Clin. Med., 9.","DOI":"10.3390\/jcm9020547"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1080\/15592294.2016.1276681","article-title":"Vitamin D limits inflammation-linked microRNA expression in adipocytes in vitro and in vivo: A new mechanism for the regulation of inflammation by vitamin D","volume":"13","author":"Karkeni","year":"2018","journal-title":"Epigenetics"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1097\/00002281-200403000-00016","article-title":"Fibromyalgia pain: Do we know the source?","volume":"16","author":"Staud","year":"2004","journal-title":"Curr. Opin. Rheumatol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1136\/ard.2008.090456","article-title":"Vitamin D and chronic widespread pain in a white middle-aged British population: Evidence from a cross-sectional population survey","volume":"68","author":"Atherton","year":"2008","journal-title":"Ann. Rheum. Dis."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1111\/papr.12252","article-title":"Cerebrospinal Fluid Cytokines and Neurotrophic Factors in Human Chronic Pain Populations: A Comprehensive Review","volume":"16","author":"Bjurstrom","year":"2014","journal-title":"Pain Pr."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1080\/17512433.2022.2081151","article-title":"The efficacy of vitamin D in treatment of fibromyalgia: A meta-analysis of randomized controlled studies and systematic review","volume":"15","author":"Qu","year":"2022","journal-title":"Expert Rev. Clin. Pharmacol."},{"key":"ref_30","first-page":"105906","article-title":"The PRISMA 2020 statement: An updated guideline for reporting systematic reviews","volume":"89","author":"Page","year":"2021","journal-title":"Syst. Rev."},{"key":"ref_31","first-page":"12","article-title":"Diffuse Musculoskeletal Pain Is Not Associated With Low Vitamin D Levels or Improved by Treatment With Vitamin D","volume":"14","author":"Warner","year":"2008","journal-title":"Am. J. Clin. Oncol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"2825","DOI":"10.1007\/s10067-017-3754-y","article-title":"Effect of vitamin D supplementation in chronic widespread pain: A systematic review and meta-analysis","volume":"36","author":"Yong","year":"2017","journal-title":"Clin. Rheumatol."},{"key":"ref_33","first-page":"295","article-title":"THU0327\u2005Efficacy of Vitamin D Supplementation in the Treatment of Fibromyalgia: Randomized Controlled Trial","volume":"73","author":"Helmii","year":"2014","journal-title":"Ann. Rheum. Dis."},{"key":"ref_34","first-page":"1333","article-title":"Fibromyalgia, bone density and vitamin D deficiency","volume":"17","author":"Mole","year":"2002","journal-title":"J. Bone Miner. Res."},{"key":"ref_35","first-page":"307","article-title":"Fibromyalgia, bone density and vitamin D deficiency","volume":"62","author":"Mole","year":"2003","journal-title":"Ann. Rheum. Dis."},{"key":"ref_36","first-page":"331","article-title":"The relation between vitamin D deficiency and fibromyalgia syndrome","volume":"33","year":"2012","journal-title":"Saudi Med. J."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.ejr.2019.05.002","article-title":"Vitamin D deficiency and treatment in Iraqi patients with primary fibromyalgia syndrome","volume":"42","author":"Aldaoseri","year":"2020","journal-title":"Egypt. Rheumatol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1007\/s42399-021-01105-w","article-title":"Prevalence of Vitamin D Deficiency and Its Relationship with Clinical Outcomes in Patients with Fibromyalgia: A Systematic Review of the Literature","volume":"4","author":"Ali","year":"2022","journal-title":"SN Compr. Clin. Med."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1136\/annrheumdis-2016-eular.2289","article-title":"Haplotypes of vitamin d receptor gene: Both risky and protective for fibromiyalgia (FMS)","volume":"75","author":"Balkarli","year":"2016","journal-title":"Ann. Rheum. Dis."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.4065\/79.12.1585","article-title":"Vitamin D deficiency is not associated with nonspecific musculoskeletal pain syndromes including fibromyalgia","volume":"79","author":"Block","year":"2004","journal-title":"Mayo Clin Proc"},{"key":"ref_41","first-page":"S306","article-title":"Fibromyalgia and vitamin D deficiency: Is there a correlation","volume":"50","author":"Braun","year":"2004","journal-title":"Arthritis Rheum."},{"key":"ref_42","first-page":"379","article-title":"Vitamin D Supplementation Seems to Improve Fibromyalgia Symptoms: Preliminary Results","volume":"20","author":"Aires","year":"2018","journal-title":"Isr. Med. Assoc. J."},{"key":"ref_43","first-page":"S134","article-title":"Complementary and alternative medicine in fibromyalgia: A practical clinical debate of agreements and contrasts","volume":"31","author":"Cassisi","year":"2013","journal-title":"Clin. Exp. Rheumatol."},{"key":"ref_44","first-page":"712","article-title":"Fibromyalgia\u2014Should we be testing and treating for vitamin D deficiency?","volume":"40","author":"Daniel","year":"2011","journal-title":"Aust. Fam. Physician"},{"key":"ref_45","unstructured":"Dogru, A., Balkarli, A., \u00c7obankara, V., Sahin, M., and Tunc, S. (2016). Effects of vitamin d therapy on quality of life in patients with fibromyalgia [Conference Object]. Ann. Rheum. Dis."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"3470","DOI":"10.1093\/pm\/pnz377","article-title":"Fibromyalgia Symptom Severity and Psychosocial Outcomes in Fibromyalgia Patients with Hypovitaminosis D: A Prospective Questionnaire Study","volume":"21","author":"Lin","year":"2020","journal-title":"Pain Med."},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Ellis, S.D., Kelly, S.T., Shurlock, J.H., and Hepburn, A.L.N. (2018). The role of vitamin D testing and replacement in fibromyalgia: A systematic literature review. BMC Rheumatol., 2.","DOI":"10.1186\/s41927-018-0035-6"},{"key":"ref_48","first-page":"E877","article-title":"Is serum hypovitaminosis D associated with chronic widespread pain including fibromyalgia? A meta-analysis of observational studies","volume":"18","author":"Hsiao","year":"2015","journal-title":"Pain Physician"},{"key":"ref_49","first-page":"S248","article-title":"Vitamin D in female systemic lupus erythematosus and fibromyalgia patients","volume":"43","author":"Huisman","year":"2000","journal-title":"Arthritis Rheum."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.apunts.2017.07.001","article-title":"Therapeutic physical exercise and supplements to treat fibromyalgia","volume":"53","year":"2018","journal-title":"Apunt. Med. l\u2019Esport"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11916-013-0355-6","article-title":"The Role of Vitamin D in Pathophysiology and Treatment of Fibromyalgia","volume":"17","author":"Jesus","year":"2013","journal-title":"Curr. Pain Headache Rep."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"2260","DOI":"10.1093\/nutrit\/nuac036","article-title":"Review of nutritional approaches to fibromyalgia","volume":"80","author":"Kadayifci","year":"2022","journal-title":"Nutr. Rev"},{"key":"ref_53","doi-asserted-by":"crossref","unstructured":"Karras, S., Rapti, E., Matsoukas, S., and Kotsa, K. (2016). Vitamin D in fibromyalgia: A causative or confounding biological interplay?. Nutrients, 8.","DOI":"10.3390\/nu8060343"},{"key":"ref_54","first-page":"181","article-title":"Early replacement of vitamin D in vitamin D-deficient fibromyalgia patients improves reported pain and number of tender points","volume":"55","author":"Khan","year":"2016","journal-title":"Rheumatology"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"164","DOI":"10.3109\/10582452.2011.582984","article-title":"Fibromyalgia syndrome and Vitamin D","volume":"19","author":"Lewis","year":"2011","journal-title":"J. Musculoskelet. Pain"},{"key":"ref_56","doi-asserted-by":"crossref","unstructured":"Lombardo, M., Feraco, A., Ottaviani, M., Rizzo, G., Camajani, E., Caprio, M., and Armani, A. (2022). The Efficacy of Vitamin D Supplementation in the Treatment of Fibromyalgia Syndrome and Chronic Musculoskeletal Pain. Nutrients, 14.","DOI":"10.3390\/nu14153010"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1089\/dna.2017.3817","article-title":"Vitamin D supplementation prevents placental ischemia induced endothelial dysfunction by downregulating placental soluble FMS-like tyrosine kinase-1","volume":"36","author":"Ma","year":"2017","journal-title":"DNA Cell Biol."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1111\/1756-185X.12878","article-title":"Relationship between FokI polymorphism in the vitamin D receptor gene and fibromyalgia syndrome","volume":"19","author":"Ozdolap","year":"2016","journal-title":"Int. J. Rheum. Dis."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1300\/J104v32n01_11","article-title":"Potential clinical benefit of nutritional supplements in the management of fibromyalgia","volume":"7","author":"Martin","year":"1999","journal-title":"J. Musculoskelet. Pain"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1093\/nutrit\/nuz033","article-title":"Is hypovitaminosis D associated with fibromyalgia? A systematic review","volume":"78","author":"Martins","year":"2020","journal-title":"Nutr. Rev."},{"key":"ref_61","first-page":"925","article-title":"The relation between vitamin D deficiency and fibromyalgia syndrome in women","volume":"32","author":"Matthana","year":"2011","journal-title":"Saudi Med. J."},{"key":"ref_62","first-page":"331","article-title":"The relation between vitamin D deficiency and fibromyalgia syndrome Reply","volume":"33","author":"Matthana","year":"2012","journal-title":"Saudi Med. J."},{"key":"ref_63","first-page":"143","article-title":"How do you treat fibromyalgia in your practice?","volume":"20","author":"Miao","year":"2008","journal-title":"Med. Acupunct."},{"key":"ref_64","first-page":"E877","article-title":"Fibromyalgia and vitamin D levels","volume":"24","year":"2017","journal-title":"Rev. La Soc. Esp. Dolor"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.pop.2010.07.007","article-title":"Fibromyalgia: Helping your patient while maintaining your sanity","volume":"37","author":"Motley","year":"2010","journal-title":"Prim. Care Clin. Off. Pract."},{"key":"ref_66","first-page":"577","article-title":"Vitamin D deficiency in multicultural primary care: A case series of 299 patients","volume":"57","author":"Mytton","year":"2007","journal-title":"Br. J. Gen. Pract."},{"key":"ref_67","unstructured":"NCT (2023, March 07). Valuation of Efficacy and Safety of Vitamin D3 Use in 80 Women Diagnosed With Fibromyalgia. Using FIQ Score and VAS, Available online: https:\/\/clinicaltrials.gov\/show\/NCT03369379."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1186\/s13023-020-01434-4","article-title":"The international X-linked hypophosphataemia (XLH) registry (NCT03193476): Rationale for and description of an international, observational study","volume":"15","author":"Padidela","year":"2020","journal-title":"Orphanet. J. Rare. Dis."},{"key":"ref_69","doi-asserted-by":"crossref","unstructured":"Pagliai, G., Giangrandi, I., Dinu, M., Sofi, F., and Colombini, B. (2020). Nutritional Interventions in the Management of Fibromyalgia Syndrome. Nutrients, 12.","DOI":"10.3390\/nu12092525"},{"key":"ref_70","first-page":"e27113","article-title":"Relationship Between Vitamin D Receptor Gene BsmI Polymorphism and Fibromyalgia Syndrome","volume":"14","author":"Parvez","year":"2022","journal-title":"Cureus"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.4065\/79.12.1586","article-title":"Vitamin D deficiency is not associated with nonspecific musculoskeletal pain syndromes including fibromyalgia\u2014Reply","volume":"79","author":"Plotnikoff","year":"2004","journal-title":"Mayo Clin. Proc."},{"key":"ref_72","first-page":"S117","article-title":"Fibromyalgia and nutrition: What news?","volume":"33","author":"Rossi","year":"2015","journal-title":"Clin. Exp. Rheumatol."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"237","DOI":"10.2217\/ijr.14.16","article-title":"Fibromyalgia: Could vitamin D help?","volume":"9","author":"Scheuer","year":"2014","journal-title":"Int. J. Clin. Rheumatol."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.injr.2012.10.007","article-title":"Vitamin D deficiency: A \u2018Blindspot\u2019 for clinicians and a veritable \u2018Ray\u2019 of hope for patients with chronic musculoskeletal pains?","volume":"7","author":"Shanmuganandan","year":"2012","journal-title":"Indian J. Rheumatol."},{"key":"ref_75","doi-asserted-by":"crossref","unstructured":"Siracusa, R., Di Paola, R., Cuzzocrea, S., and Impellizzeri, D. (2021). Fibromyalgia: Pathogenesis, mechanisms, diagnosis and treatment options update. Int. J. Mol. Sci., 22.","DOI":"10.3390\/ijms22083891"},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1136\/annrheumdis-2022-eular.5289","article-title":"Vitamin D supplementation in fibromyalgia: A systematic review","volume":"81","author":"Sousa","year":"2022","journal-title":"Ann. Rheum. Dis."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1300\/J094v15n01_07","article-title":"Fibromyalgia syndrome review","volume":"15","author":"Spaeth","year":"2007","journal-title":"J. Musculoskelet. Pain"},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.pain.2008.11.010","article-title":"Vitamin D and chronic pain","volume":"141","author":"Straube","year":"2009","journal-title":"Pain"},{"key":"ref_79","doi-asserted-by":"crossref","unstructured":"Straube, S., Derry, S., Straube, C., and Moore, R.A. (2015). Vitamin D for the treatment of chronic painful conditions in adults. Cochrane Database Syst. Rev., 2015.","DOI":"10.1002\/14651858.CD007771.pub3"},{"key":"ref_80","first-page":"6","article-title":"One year in review 2017: Fibromyalgia","volume":"35","author":"Talotta","year":"2017","journal-title":"Clin. Exp. Rheumatol."},{"key":"ref_81","first-page":"53","article-title":"The effects of bone mineral density and level of serum vitamin-D on pain and quality of life in fibromialgia patients","volume":"16","year":"2010","journal-title":"Osteoporoz Dunya."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1038\/nrrheum.2016.25","article-title":"Neuroinflammation in fibromyalgia and CRPS is multifactorial","volume":"12","author":"Vasquez","year":"2016","journal-title":"Nat. Rev. Rheumatol."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"S131","DOI":"10.1016\/j.bone.2008.10.016","article-title":"Vitamin D levels on patients with Fibromyalgia","volume":"43","author":"Velozo","year":"2008","journal-title":"Bone"},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"317","DOI":"10.2174\/1573397118666220307122152","article-title":"Efficacy of Vitamin D Supplementation in the Improvement of Clinical Status in Pa-tients Diagnosed with Fibromyalgia Syndrome: A Systematic Review","volume":"18","author":"Venkatesan","year":"2022","journal-title":"Curr. Rheumatol. Rev."},{"key":"ref_85","doi-asserted-by":"crossref","unstructured":"Vittorio, S., Erica, S., Cinzia, C., Alvise, M., Elena, M., Alessandro, P., Enrico, P., Katia, D., Teresa, V.M., and Luca, D.C. (2020). Comparison between Acupuncture and Nutraceutical Treatment with Migratens((R)) in Patients with Fibromyalgia Syndrome: A Prospective Randomized Clinical Trial. Nutrients, 12.","DOI":"10.3390\/nu12030821"},{"key":"ref_86","first-page":"S517","article-title":"Treatment with vitamin D does not reduce pain in fibromyalgia patients with low vitamin D levels","volume":"52","author":"Warner","year":"2005","journal-title":"Arthritis Rheum."},{"key":"ref_87","first-page":"415","article-title":"Effect of Vitamin D Supplementation on Pain: A Systematic Review and Meta-analysis","volume":"19","author":"Wu","year":"2016","journal-title":"Pain Physician"},{"key":"ref_88","first-page":"S108","article-title":"Effects of vitamin D on quality of life in fibromyalgia patients: A randomized controlled trial","volume":"26","author":"Zabihiyeganeh","year":"2015","journal-title":"Osteoporos. Int."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.survophthal.2020.05.006","article-title":"Fibromyalgia syndrome and the eye-A review","volume":"66","author":"Zdebik","year":"2021","journal-title":"Surv. Ophthalmol."},{"key":"ref_90","doi-asserted-by":"crossref","unstructured":"Higgins, J., Thomas, J., Chandler, J., Cumpston, M., Li, T., Page, M., and Welch, V. (2019). Cochrane Handbook for Systematic Reviews of Interventions, John Wiley & Sons. [2nd ed.].","DOI":"10.1002\/9781119536604"},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"80","DOI":"10.13105\/wjma.v5.i4.80","article-title":"Assessing the quality of studies in meta-analyses: Advantages and limitations of the Newcastle Ottawa Scale","volume":"5","author":"Luchini","year":"2017","journal-title":"World J. Meta Anal."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"203","DOI":"10.4158\/EP.15.3.203","article-title":"Correlation of Symptoms with Vitamin D Deficiency and Symptom Response to Cholecalciferol Treatment: A Randomized Controlled Trial","volume":"15","author":"Arvold","year":"2009","journal-title":"Endocr. Pr."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.pain.2013.10.002","article-title":"Effects of vitamin D on patients with fibromyalgia syndrome: A randomized placebo-controlled trial","volume":"155","author":"Wepner","year":"2014","journal-title":"Pain"},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"167","DOI":"10.14196\/mjiri.32.29","article-title":"Effects of vitamin D optimization on quality of life of patients with fibromyalgia: A randomized controlled trial","volume":"32","author":"Mirzaei","year":"2018","journal-title":"Med J. Islam. Repub. Iran"},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"3257","DOI":"10.1007\/s10067-021-05640-8","article-title":"Efficacy and safety of weekly vitamin D3 in patients with fibromyalgia: 12-week, double-blind, randomized, controlled placebo trial","volume":"40","year":"2021","journal-title":"Clin. Rheumatol."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"2591","DOI":"10.1016\/j.pain.2014.09.024","article-title":"Effect of vitamin D on musculoskeletal pain and headache: A randomized, double-blind, placebo-controlled trial among adult ethnic minorities in Norway","volume":"155","author":"Knutsen","year":"2014","journal-title":"Pain"},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1111\/1756-185X.12960","article-title":"Efficacy of vitamin D replacement therapy on patients with chronic nonspecific widespread musculoskeletal pain with vitamin D deficiency","volume":"19","author":"Yilmaz","year":"2016","journal-title":"Int. J. Rheum. Dis."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"113","DOI":"10.5152\/eurasianjmed.2017.16283","article-title":"Effects of Vitamin D Therapy on Quality of Life in Patients with Fibromyalgia","volume":"49","author":"Dogru","year":"2017","journal-title":"Eurasian J. Med."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1002\/art.1780330203","article-title":"The American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia. Report of the Multicenter Criteria Committee","volume":"33","author":"Wolfe","year":"1990","journal-title":"Arthritis Rheumatol."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.3899\/jrheum.100594","article-title":"Fibromyalgia Criteria and Severity Scales for Clinical and Epidemiological Studies: A Modification of the ACR Preliminary Diagnostic Criteria for Fibromyalgia","volume":"38","author":"Wolfe","year":"2011","journal-title":"J. Rheumatol."},{"key":"ref_101","doi-asserted-by":"crossref","unstructured":"Von Hippel, P.T. (2015). The heterogeneity statistic I2 can be biased in small meta-analyses. BMC Med. Res. Methodol., 15.","DOI":"10.1186\/s12874-015-0024-z"},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"117","DOI":"10.2147\/PRBM.S178240","article-title":"Psychological impact of fibromyalgia: Current perspectives","volume":"12","author":"Duschek","year":"2019","journal-title":"Psychol. Res. Behav. Manag."},{"key":"ref_103","unstructured":"Ware, J.E., Snow, K.K., Kosinski, M., and Gandek, B. (1993). SF-36 Health Survey. Manual and Interpretation Guide, The Health Institute."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1097\/00005650-199206000-00002","article-title":"The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection","volume":"30","author":"Ware","year":"1992","journal-title":"Med. Care"},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"S26","DOI":"10.1016\/0002-9343(92)90133-V","article-title":"Comorbidity of gastrointestinal complaints, depression, and anxiety in the epidemiologic catchment area (ECA) study","volume":"92","author":"Walker","year":"1992","journal-title":"Am. J. Med."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0304-3959(03)00301-4","article-title":"Mood and anxiety disorders associated with chronic pain: An examination in a nationally representative sample","volume":"106","author":"McWilliams","year":"2003","journal-title":"Pain"},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"E495","DOI":"10.1097\/BRS.0b013e31810768fc","article-title":"Comorbidity and Impact of Chronic Spinal Pain in Nigeria","volume":"32","author":"Gureje","year":"2007","journal-title":"Spine"},{"key":"ref_108","first-page":"476","article-title":"The global prevalence of common mental disorders: A systematic review and meta-analysis 1980\u20132013","volume":"43","author":"Steel","year":"2014","journal-title":"Leuk. Res."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1097\/HRP.0000000000000198","article-title":"Pain and Depression: A Systematic Review","volume":"26","author":"Ishak","year":"2018","journal-title":"Harv. Rev. Psychiatry"},{"key":"ref_110","first-page":"882","article-title":"For The New Zealand Mental Health Survey Research Team Mental-Physical Comorbidity in Te Rau Hinengaro: The New Zealand Mental Health Survey","volume":"40","author":"Scott","year":"2006","journal-title":"Aust. New Zealand J. Psychiatry"},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"2433","DOI":"10.1001\/archinte.163.20.2433","article-title":"Depression and Pain Comorbidity: A literature review","volume":"163","author":"Bair","year":"2003","journal-title":"Arch. Intern. Med."},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1002\/art.38191","article-title":"Disrupted Brain Circuitry for Pain-Related Reward\/Punishment in Fibromyalgia","volume":"66","author":"Loggia","year":"2013","journal-title":"Arthritis Rheumatol."},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"9957","DOI":"10.1523\/JNEUROSCI.4605-14.2015","article-title":"Chronic Back Pain Is Associated with Alterations in Dopamine Neurotransmission in the Ventral Striatum","volume":"35","author":"Martikainen","year":"2015","journal-title":"J. Neurosci."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.biopsych.2014.10.026","article-title":"Inflammatory Factors Mediate Vulnerability to a Social Stress-Induced Depressive-like Phenotype in Passive Coping Rats","volume":"78","author":"Wood","year":"2014","journal-title":"Biol. Psychiatry"},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1124\/pr.113.008144","article-title":"Neuroinflammation and Comorbidity of Pain and Depression","volume":"66","author":"Walker","year":"2013","journal-title":"Pharmacol. Rev."},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"643609","DOI":"10.3389\/fpsyt.2021.643609","article-title":"Comorbid Chronic Pain and Depression: Shared Risk Factors and Differential Antidepressant Effectiveness","volume":"12","author":"Roughan","year":"2021","journal-title":"Front. Psychiatry"},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.genhosppsych.2009.07.002","article-title":"Axis I and Axis II psychiatric disorders in patients with fibromyalgia","volume":"32","author":"Uguz","year":"2010","journal-title":"Gen. Hosp. Psychiatry"},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.4088\/JCP.v67n0807","article-title":"Comorbidity of Fibromyalgia and Psychiatric Disorders","volume":"67","author":"Arnold","year":"2006","journal-title":"J. Clin. Psychiatry"},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.jad.2010.07.004","article-title":"Fibromyalgia syndrome and depressive symptoms: Comorbidity and clinical correlates","volume":"128","author":"Aguglia","year":"2011","journal-title":"J. Affect. Disord."},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1056\/NEJMe1206858","article-title":"Vitamin D\u2014Baseline Status and Effective Dose","volume":"367","author":"Heaney","year":"2012","journal-title":"New Engl. J. Med."},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.3390\/nu6041501","article-title":"Vitamin D and Depression: A Systematic Review and Meta-Analysis Comparing Studies with and without Biological Flaws","volume":"6","author":"Spedding","year":"2014","journal-title":"Nutrients"},{"key":"ref_122","first-page":"i158","article-title":"279. Association Between Vitamin D and Multiple Symptom Domains in Fibromyalgia","volume":"54","author":"Singh","year":"2015","journal-title":"Rheumatology"},{"key":"ref_123","first-page":"523","article-title":"Relationship between seasonal serum 25-hydroxyvitamin d levels and disease activity in patients with ankylosing spondylitis, osteoarthritis and fibromyalgia syndrome","volume":"8","author":"Ozkan","year":"2017","journal-title":"J. Clin. Anal. Med."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"329","DOI":"10.5152\/tftrd.2014.45143","article-title":"Vitamin D Levels in Women with Fibromyalgia and Relationship between Pain, Depression, and Sleep","volume":"60","author":"Aras","year":"2014","journal-title":"Turk. J. Phys. Med. 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