{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:04:50Z","timestamp":1760148290293,"version":"build-2065373602"},"reference-count":17,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2023,4,18]],"date-time":"2023-04-18T00:00:00Z","timestamp":1681776000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Pyoderma gangrenosum (PG) is an uncommon inflammatory skin disorder typically presenting as painful skin ulcers, which may also exhibit extracutaneous findings. PG can occur at the site of trauma or surgery, which is known as the pathergic phenomenon. A 36-year-old man developed bilateral steroid-induced glaucoma after prolonged systemic immunosuppressive treatment for cutaneous pyoderma gangrenosum. After successful Ahmed glaucoma valve implantation surgery with donor scleral patch graft in the right eye, the same surgery failed repeatedly in the left eye and complicated with the prolonged conjunctival necrosis and the exposure of the donor scleral patch graft. Under the impression of ocular involvement of PG, microinvasive glaucoma surgery (MIGS) with XEN\u00ae Gel Stent was performed in the left eye; the conjunctival bleb was successfully formed without conjunctival necrosis, and intraocular pressure was well maintained. Ophthalmic surgery can be complicated in patients with PG, and the surgical option should be selected prudently to minimize surgical trauma. MIGS, as a minimally invasive surgical technique, could offer an advantage for patients with PG.<\/jats:p>","DOI":"10.3390\/jcm12082930","type":"journal-article","created":{"date-parts":[[2023,4,18]],"date-time":"2023-04-18T05:18:13Z","timestamp":1681795093000},"page":"2930","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Management of Steroid-Induced Glaucoma in a Patient with Pyoderma Gangrenosum"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4519-9474","authenticated-orcid":false,"given":"Ji Yeon","family":"Byun","sequence":"first","affiliation":[{"name":"Department of Dermatology, Ewha Womans University College of Medicine, Seoul 07804, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong Koo","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, School of Medicine, Kyungpook National University, Daegu 41944, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1706-007X","authenticated-orcid":false,"given":"Yong Hyun","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Dermatology, School of Medicine, Kyungpook National University, Daegu 41944, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Kook","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9155-5092","authenticated-orcid":false,"given":"Dai Woo","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, School of Medicine, Kyungpook National University, Daegu 41944, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1134939","DOI":"10.3389\/fmed.2023.1134939","article-title":"Practical aspects of the diagnosis and management of pyoderma gangrenosum","volume":"10","author":"Chen","year":"2023","journal-title":"Front. Med."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"191","DOI":"10.2165\/11595240-000000000-00000","article-title":"Etiology and management of pyoderma gangrenosum: A comprehensive review","volume":"13","author":"Ahronowitz","year":"2012","journal-title":"Am. J. Clin. Dermatol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/s00403-019-01912-1","article-title":"Extracutaneous involvement of pyoderma gangrenosum","volume":"311","author":"Borda","year":"2019","journal-title":"Arch. Dermatol. Res."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1080\/01676830.2017.1353114","article-title":"Pyoderma gangrenosum affecting the eye, orbit, and adnexa. A review","volume":"37","author":"McElnea","year":"2018","journal-title":"Orbit"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1001\/jamadermatol.2017.5980","article-title":"Diagnostic Criteria of Ulcerative Pyoderma Gangrenosum: A Delphi Consensus of International Experts","volume":"154","author":"Maverakis","year":"2018","journal-title":"JAMA Dermatol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1111\/j.1468-3083.2009.03199.x","article-title":"Pyoderma gangrenosum: An updated review","volume":"23","author":"Ruocco","year":"2009","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.jaad.2016.08.049","article-title":"Ocular pyoderma gangrenosum: A systematic review","volume":"76","author":"Gupta","year":"2017","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1159\/000328630","article-title":"Steroid-induced iatrogenic glaucoma","volume":"47","author":"Razeghinejad","year":"2012","journal-title":"Ophthalmic Res."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1177\/000313481107701236","article-title":"A retrospective study of 12 cases of pyoderma gangrenosum: Why we should avoid surgical intervention and what therapy to apply","volume":"77","author":"Kakol","year":"2011","journal-title":"Am. Surg."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1046\/j.1524-4725.2000.0260111063.x","article-title":"Surgical management of pyoderma gangrenosum: Case report and review","volume":"26","author":"Alam","year":"2000","journal-title":"Dermatol. Surg."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1097\/SAP.0b013e31829565f3","article-title":"Inpatient management of pyoderma gangrenosum: Treatments, outcomes, and clinical implications","volume":"74","author":"Cabalag","year":"2015","journal-title":"Ann. Plast. Surg."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1097\/00000637-200101000-00005","article-title":"A rationale for adjuvant surgical intervention in pyoderma gangrenosum","volume":"46","author":"Kaddoura","year":"2001","journal-title":"Ann. Plast. Surg."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1097\/01.ijg.0000169391.94555.c1","article-title":"Incidence and management of encapsulated cysts following Ahmed glaucoma valve insertion","volume":"14","author":"Schertzer","year":"2005","journal-title":"J. Glaucoma"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1097\/00004397-200040010-00015","article-title":"Complications of glaucoma drainage implant surgery","volume":"40","author":"Guerrero","year":"2000","journal-title":"Int. Ophthalmol. Clin."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Lavia, C., Dallorto, L., Maule, M., Ceccarelli, M., and Fea, A.M. (2017). Minimally-invasive glaucoma surgeries (MIGS) for open angle glaucoma: A systematic review and meta-analysis. PLoS ONE, 12.","DOI":"10.1371\/journal.pone.0183142"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.2147\/OPTH.S178348","article-title":"XEN\u00ae Gel Stent: A comprehensive review on its use as a treatment option for refractory glaucoma","volume":"14","author":"Fea","year":"2020","journal-title":"Clin. Ophthalmol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.ajo.2017.07.023","article-title":"Performance and safety of a new ab interno gelatin stent in refractory glaucoma at 12 months","volume":"183","author":"Grover","year":"2017","journal-title":"Am. J. Ophthalmol."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/12\/8\/2930\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:17:59Z","timestamp":1760123879000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/12\/8\/2930"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,18]]},"references-count":17,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2023,4]]}},"alternative-id":["jcm12082930"],"URL":"https:\/\/doi.org\/10.3390\/jcm12082930","relation":{},"ISSN":["2077-0383"],"issn-type":[{"type":"electronic","value":"2077-0383"}],"subject":[],"published":{"date-parts":[[2023,4,18]]}}}