{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T07:43:43Z","timestamp":1773215023333,"version":"3.50.1"},"reference-count":42,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T00:00:00Z","timestamp":1682467200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Netherlands Organization for Health Research and Development"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Psychotropic drugs (PD) are often prescribed to nursing home residents with Korsakoff syndrome (KS). It is unknown whether these drugs are prescribed correctly or whether they are prescribed off-label, for example, to treat behavioral symptoms. To get more insight into PD prescriptions, a descriptive study was performed. The type, category and indications of PD prescriptions of 285 participants were analyzed using medication charts and questionnaires. Behavioral symptoms were investigated with the Neuropsychiatric Inventory-Questionnaire. The results showed that atypical antipsychotics (57.1%) were prescribed more frequently than typical antipsychotics (49.3%). Of the antidepressants, selective serotonin\/norepinephrine reuptake inhibitors (63.1%) were most frequently prescribed, followed by tricyclic antidepressants (23.4%). Of the benzodiazepines, anxiolytics (85.7%) were more prescribed than hypnotics (24.5%). Besides psychiatric disorders, PD were also prescribed to treat behavioral symptoms varying from 29.9% (antipsycho-tics) to 26.3% (benzodiazepines) and 9.3% (antidepressants). Furthermore, prescriptions were high if behavioral symptoms were present. To conclude, PD are often prescribed to residents with KS for an unapproved indication, namely behavioral symptoms. Additional research is needed to obtain further insight into the current prescribing culture and the effectiveness of PD. The insights thus obtained may, ultimately, contribute to the appropriate prescription of PD for people with KS.<\/jats:p>","DOI":"10.3390\/jcm12093133","type":"journal-article","created":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T05:23:35Z","timestamp":1682486615000},"page":"3133","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Prevalences and Indications of Psychotropic Drug Prescriptions in Nursing Home Residents with Korsakoff Syndrome"],"prefix":"10.3390","volume":"12","author":[{"given":"Ineke J.","family":"Gerridzen","sequence":"first","affiliation":[{"name":"Atlant, Korsakoff Centre of Expertise, Kuiltjesweg 1, 7361 TC Beekbergen, The Netherlands"},{"name":"Amsterdam UMC, Location Vrije Universiteit Amsterdam, Department of Medicine for Older People, De Boelelaan 1109, 1081 HV Amsterdam, The Netherlands"},{"name":"Amsterdam Public Health, Aging & Later Life, De Boelelaan 1109, 1081 HV Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Els","family":"Doejaaren","sequence":"additional","affiliation":[{"name":"Amsterdam UMC, Location Vrije Universiteit Amsterdam, Department of Medicine for Older People, De Boelelaan 1109, 1081 HV Amsterdam, The Netherlands"},{"name":"Amsterdam Public Health, Aging & Later Life, De Boelelaan 1109, 1081 HV Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth B.","family":"Veenhuizen","sequence":"additional","affiliation":[{"name":"Atlant, Korsakoff Centre of Expertise, Kuiltjesweg 1, 7361 TC Beekbergen, The Netherlands"},{"name":"Amsterdam UMC, Location Vrije Universiteit Amsterdam, Department of Medicine for Older People, De Boelelaan 1109, 1081 HV Amsterdam, The Netherlands"},{"name":"Amsterdam Public Health, Aging & Later Life, De Boelelaan 1109, 1081 HV Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cees M. P. M.","family":"Hertogh","sequence":"additional","affiliation":[{"name":"Amsterdam UMC, Location Vrije Universiteit Amsterdam, Department of Medicine for Older People, De Boelelaan 1109, 1081 HV Amsterdam, The Netherlands"},{"name":"Amsterdam Public Health, Aging & Later Life, De Boelelaan 1109, 1081 HV Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karlijn J.","family":"Joling","sequence":"additional","affiliation":[{"name":"Amsterdam UMC, Location Vrije Universiteit Amsterdam, Department of Medicine for Older People, De Boelelaan 1109, 1081 HV Amsterdam, The Netherlands"},{"name":"Amsterdam Public Health, Aging & Later Life, De Boelelaan 1109, 1081 HV Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1093\/alcalc\/agn118","article-title":"The Korsakoff syndrome: Clinical aspects, psychology and treatment","volume":"44","author":"Kopelman","year":"2009","journal-title":"Alcohol Alcohol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"2875","DOI":"10.2147\/NDT.S130078","article-title":"Korsakoff\u2019s syndrome: A critical review","volume":"13","author":"Arts","year":"2017","journal-title":"Neuropsychiatr. 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