{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T02:34:51Z","timestamp":1791513291520,"version":"4.3.4"},"reference-count":54,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2023,4,28]],"date-time":"2023-04-28T00:00:00Z","timestamp":1682640000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Nutritional support during radiotherapy is crucial to tolerating and completing oropharyngeal squamous cell carcinoma (OPSCC) treatment. The impact of HPV status on nutritional support is debated. The objective was to evaluate the rate of Reactive Feeding Tube (RFT) use and determine its prognostic factors during definitive radiotherapy for OPSCC. All OPSCC patients treated from 2009 to 2014 were included in this multicentric retrospective study. The impact of tumor p16 status on the risk of RFT was assessed through multivariate analyses. Among the 543 patients, 103 patients required an RFT (19.0%). The use of RFT differed between centers (5% to 32.4%). In multivariate analysis, only tongue base involvement and concurrent chemotherapy were significantly associated with RFT (OR = 2.18 and 3.7, respectively). Tongue base involvement and concomitant chemotherapy were prognostic factors for RFT. HPV status was not a prognostic factor for enteral nutrition during radiotherapy for OPSCC.<\/jats:p>","DOI":"10.3390\/jcm12093169","type":"journal-article","created":{"date-parts":[[2023,4,28]],"date-time":"2023-04-28T02:02:23Z","timestamp":1682647343000},"page":"3169","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Enteral Nutrition during Radiotherapy for Oropharyngeal Cancers: Prevalence and Prognostic Factors Based on HPV Status (A GETTEC Study)"],"prefix":"10.3390","volume":"12","author":[{"given":"Dorian","family":"Culi\u00e9","sequence":"first","affiliation":[{"name":"Antoine Lacassagne Centre, University Institute of the Face and Neck, C\u00f4te d\u2019Azur University, 06000 Nice, France"},{"name":"Antoine Lacassagne Centre, Department of Epidemiology, Biostatistics and Health Data, C\u00f4te d\u2019Azur University, 06000 Nice, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5104-9507","authenticated-orcid":false,"given":"Renaud","family":"Schiappa","sequence":"additional","affiliation":[{"name":"Antoine Lacassagne Centre, Department of Epidemiology, Biostatistics and Health Data, C\u00f4te d\u2019Azur University, 06000 Nice, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanguy","family":"Pace-Loscos","sequence":"additional","affiliation":[{"name":"Antoine Lacassagne Centre, Department of Epidemiology, Biostatistics and Health Data, C\u00f4te d\u2019Azur University, 06000 Nice, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Guelfucci","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Head and Neck Surgery, Sainte Musse Hospital, 83100 Toulon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4081-3922","authenticated-orcid":false,"given":"Sebastien","family":"Vergez","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Head and Neck Surgery, Cancer University Institute of Toulouse, 31100 Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renaud","family":"Garrel","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital of Montpellier, 34295 Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Fakhry","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Head and Neck Surgery, Public Assistance\u2014Hospitals of Marseille, 13005 Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Dassonville","sequence":"additional","affiliation":[{"name":"Antoine Lacassagne Centre, University Institute of the Face and Neck, C\u00f4te d\u2019Azur University, 06000 Nice, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilles","family":"Poissonnet","sequence":"additional","affiliation":[{"name":"Antoine Lacassagne Centre, University Institute of the Face and Neck, C\u00f4te d\u2019Azur University, 06000 Nice, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Lallemant","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital of N\u00eemes, 30900 N\u00eemes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Sudaka","sequence":"additional","affiliation":[{"name":"Antoine Lacassagne Centre, Department of Pathology, C\u00f4te d\u2019Azur University, 06000 Nice, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esma","family":"Saada-Bouzid","sequence":"additional","affiliation":[{"name":"Antoine Lacassagne Centre, Department of Medical Oncology, C\u00f4te d\u2019Azur University, 06000 Nice, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Benezery","sequence":"additional","affiliation":[{"name":"Antoine Lacassagne Centre, Department of Radiotherapy, C\u00f4te d\u2019Azur University, 06000 Nice, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephane","family":"Temam","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Head and Neck Surgery, Gustave Roussy Institute, 94805 Villejuif, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phillipe","family":"Gorphe","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Head and Neck 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