{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T14:52:33Z","timestamp":1773240753394,"version":"3.50.1"},"reference-count":28,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2023,5,6]],"date-time":"2023-05-06T00:00:00Z","timestamp":1683331200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Federal Ministry of Education and Research","award":["01ER1301A\/B\/C"],"award-info":[{"award-number":["01ER1301A\/B\/C"]}]},{"name":"Federal Ministry of Education and Research","award":["01 ER1511D"],"award-info":[{"award-number":["01 ER1511D"]}]},{"name":"participating universities and the institutes of the Leibniz Association","award":["01ER1301A\/B\/C"],"award-info":[{"award-number":["01ER1301A\/B\/C"]}]},{"name":"participating universities and the institutes of the Leibniz Association","award":["01 ER1511D"],"award-info":[{"award-number":["01 ER1511D"]}]},{"name":"federal states and the Helmholtz Association","award":["01ER1301A\/B\/C"],"award-info":[{"award-number":["01ER1301A\/B\/C"]}]},{"name":"federal states and the Helmholtz Association","award":["01 ER1511D"],"award-info":[{"award-number":["01 ER1511D"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Introduction: This study aimed to explore whether body mass index (BMI), systolic blood pressure (RR syst), diastolic blood pressure (RR diast) or heart rate (HR) are associated with tinnitus status and\/or severity. Methods: To that end, we evaluated the influence of tinnitus status and Tinnitus Handicap Inventory (THI) score on BMI, RR syst, RR diast and HR by comparing data from a large sample of patients presenting to a specialized tertiary referral clinic (N = 1066) with data from a population-based control group (N = 9885) by means of linear models. Results: Tinnitus patients had a significantly lower BMI and higher RR syst, RR diast and HR than non-tinnitus patients; however, the contribution of the case\u2013control status to R2 was very small (0.1%, 0.7%, 1.4% and 0.4%, respectively). BMI had little predictive power for the THI score (higher BMI scores were related to higher THI scores; R2 = 0.5%) and neither RR syst, RR diast, nor HR showed a statistically significant association with THI. Discussion: Our findings suggest that HR, RR and BMI are at most marginally associated with tinnitus status and severity.<\/jats:p>","DOI":"10.3390\/jcm12093321","type":"journal-article","created":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T02:29:22Z","timestamp":1683512962000},"page":"3321","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Tinnitus Is Marginally Associated with Body Mass Index, Heart Rate and Arterial Blood Pressure: Results from a Large Clinical Sample"],"prefix":"10.3390","volume":"12","author":[{"given":"Berthold","family":"Langguth","sequence":"first","affiliation":[{"name":"Department of Psychiatry and Psychotherapy, Bezirksklinikum, University of Regensburg, Universit\u00e4tsstra\u00dfe 84, 93053 Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3308-0652","authenticated-orcid":false,"given":"Jan","family":"Bulla","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Psychotherapy, Bezirksklinikum, University of Regensburg, Universit\u00e4tsstra\u00dfe 84, 93053 Regensburg, Germany"},{"name":"Department of Mathematics, University of Bergen, 5020 Bergen, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beate","family":"Fischer","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Preventive Medicine, University of Regensburg, 93053 Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9265-5594","authenticated-orcid":false,"given":"Hansjoerg","family":"Baurecht","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Preventive Medicine, University of Regensburg, 93053 Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6208-7821","authenticated-orcid":false,"given":"Martin","family":"Schecklmann","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Psychotherapy, Bezirksklinikum, University of Regensburg, Universit\u00e4tsstra\u00dfe 84, 93053 Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7639-5318","authenticated-orcid":false,"given":"Steven C.","family":"Marcrum","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, University of Regensburg, 93053 Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veronika","family":"Vielsmeier","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, University of Regensburg, 93053 Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1001\/jamaneurol.2022.2189","article-title":"Global Prevalence and Incidence of Tinnitus: A Systematic Review and Meta-analysis","volume":"79","author":"Jarach","year":"2022","journal-title":"JAMA Neurol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/bs.pbr.2020.12.002","article-title":"Tinnitus and tinnitus disorder: Theoretical and operational definitions (an international multidisciplinary proposal)","volume":"260","author":"Schlee","year":"2021","journal-title":"Prog. 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