{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T01:09:52Z","timestamp":1789780192974,"version":"4.0.1"},"reference-count":32,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T00:00:00Z","timestamp":1684368000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"CEAUL\u2014Centro de Estat\u00edstica e Aplica\u00e7\u00f5es, Faculdade de Ci\u00eancias, Universidade de Lisboa, Portugal financed by national funds through FCT\u2014Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","award":["UIDB\/00006\/2020"],"award-info":[{"award-number":["UIDB\/00006\/2020"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Temporomandibular joint disorders (TMDs) are characterized by their multifactorial etiology and pathogenesis. A 3-year prospective study was conducted in a Portuguese TMDs department to study the prevalence of different TMDs signs and symptoms and their association with risk factors and comorbidities. Five hundred ninety-five patients were included using an online database: EUROTMJ. Most patients were female (80.50%), with a mean age of 38.20 \u00b1 15.73 years. The main complaints were: (1) temporomandibular joint (TMJ) clicking (13.26%); (2) TMJ pain (12.49%); (3) masticatory muscle tension (12.15%). The main clinical findings were myalgia (74%), TMJ clicking (60\u201362%), and TMJ arthralgia (31\u201336%). Risk factors such as clenching (60%) and bruxism (30%) were positively associated with TMJ pain and myalgia. Orthodontic treatment (20%) and wisdom tooth removal (19%) were positively associated with TMJ clicking, while jaw trauma (6%), tracheal intubation (4%) and orthognathic surgery (1%) were positively associated with TMJ crepitus, limited mandibular range of motion, and TMJ pain, respectively. In total, 42.88% of TMDs patients had other associated chronic diseases, most of them were mental behavioral or neurodevelopmental disorders (33.76%), namely, anxiety (20%) and depression (13%). The authors also observed a positive association of mental disorders with the degree of TMJ pain and myalgia. The online database seems to be a relevant scientific instrument for healthcare providers who treat TMDs. The authors expect that the EUROTMJ database can serve as a milestone for other TMDs departments.<\/jats:p>","DOI":"10.3390\/jcm12103553","type":"journal-article","created":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T00:55:29Z","timestamp":1684457729000},"page":"3553","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Prevalence of Clinical Signs and Symptoms of Temporomandibular Joint Disorders Registered in the EUROTMJ Database: A Prospective Study in a Portuguese Center"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8411-9946","authenticated-orcid":false,"given":"David Faustino","family":"\u00c2ngelo","sequence":"first","affiliation":[{"name":"Instituto Portugu\u00eas da Face, 1050-227 Lisboa, Portugal"},{"name":"Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisboa, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz","family":"Mota","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Estomatologia, Centro Hospitalar Universit\u00e1rio Lisboa Norte (CHULN), 1649-035 Lisboa, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo S\u00e3o","family":"Jo\u00e3o","sequence":"additional","affiliation":[{"name":"Department of Computer Science and Quantitative Methods, School of Management and Technology, Polytechnic Institute of Santar\u00e9m, 2001-904 Santar\u00e9m, Portugal"},{"name":"CEAUL\u2014Centro de Estat\u00edstica e Aplica\u00e7\u00f5es, Faculdade de Ci\u00eancias, Universidade de Lisboa, 1749-016 Lisboa, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Sanz","sequence":"additional","affiliation":[{"name":"Instituto Portugu\u00eas da Face, 1050-227 Lisboa, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5750-2875","authenticated-orcid":false,"given":"Henrique Jos\u00e9","family":"Cardoso","sequence":"additional","affiliation":[{"name":"Instituto Portugu\u00eas da Face, 1050-227 Lisboa, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"106","DOI":"10.4103\/njms.NJMS_73_17","article-title":"Temporomandibular disorders in North Indian population visiting a tertiary care dental hospital","volume":"11","author":"Chaurasia","year":"2020","journal-title":"Natl. J. Maxillofac. Surg."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1080\/00016357.2020.1746395","article-title":"Prevalence of clinical signs and pain symptoms of temporomandibular disorders and associated factors in adult Finns","volume":"78","author":"Qvintus","year":"2020","journal-title":"Acta Odontol. Scand."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1111\/joor.12803","article-title":"Prevalence of temporomandibular disorder pain, jaw noises and oral behaviours in an adult Italian population sample","volume":"46","author":"Iodice","year":"2019","journal-title":"J. Oral. Rehabil."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/s13005-020-00234-2","article-title":"Prevalence of temporomandibular joint disorder in the Lebanese population, and its association with depression, anxiety, and stress","volume":"16","author":"Kmeid","year":"2020","journal-title":"Head Face Med."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1007\/s00784-020-03710-w","article-title":"Prevalence of temporomandibular joint disorders: A systematic review and meta-analysis","volume":"25","author":"Valesan","year":"2021","journal-title":"Clin. Oral Investig."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.jdent.2010.01.006","article-title":"Age peaks of different RDC\/TMD diagnoses in a patient population","volume":"38","author":"Manfredini","year":"2010","journal-title":"J. Dent."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1111\/j.1365-2842.2005.01574.x","article-title":"Risk factors associated with symptoms of temporomandibular disorders in a population of 50- and 60-year-old subjects","volume":"33","author":"Johansson","year":"2006","journal-title":"J. Oral. Rehabil."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1023\/B:QURE.0000018499.64574.1f","article-title":"Is a single-item visual analogue scale as valid, reliable and responsive as multi-item scales in measuring quality of life?","volume":"13","author":"Stalmeier","year":"2004","journal-title":"Qual. Life Res. Int. J. Qual. Life Asp. Treat. Care Rehabil."},{"key":"ref_9","first-page":"63","article-title":"The Research Diagnostic Criteria for Temporomandibular Disorders. V: Methods used to establish and validate revised Axis I diagnostic algorithms","volume":"24","author":"Schiffman","year":"2010","journal-title":"J. Orofac. Pain"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"6","DOI":"10.11607\/jop.1151","article-title":"Diagnostic Criteria for Temporomandibular Disorders (DC\/TMD) for Clinical and Research Applications: Recommendations of the International RDC\/TMD Consortium Network* and Orofacial Pain Special Interest Group","volume":"28","author":"Schiffman","year":"2014","journal-title":"J. Oral Facial Pain Headache"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.archoralbio.2017.06.029","article-title":"Does pain in the masseter and anterior temporal muscles influence maximal bite force?","volume":"83","author":"Goiato","year":"2017","journal-title":"Arch. Oral Biol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"e245120","DOI":"10.1136\/bcr-2021-245120","article-title":"Multidisciplinary management of temporomandibular joint ankylosis in an adult: Journey from arthroplasty to oral rehabilitation","volume":"14","author":"Kothari","year":"2021","journal-title":"BMJ Case Rep."},{"key":"ref_13","first-page":"143","article-title":"Prevalence of signs and symptoms of temporomandibular disorders in an urban and rural German population: Results of a population-based Study of Health in Pomerania","volume":"35","author":"Gesch","year":"2004","journal-title":"Quintessence Int."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/1746-160X-2-25","article-title":"Signs and symptoms of temporomandibular disorders and oral parafunctions in urban Saudi Arabian adolescents: A research report","volume":"2","author":"Feteih","year":"2006","journal-title":"Head Face Med."},{"key":"ref_15","first-page":"270","article-title":"Symptoms of temporomandibular disorders in the population: An epidemiological study","volume":"24","author":"Campos","year":"2010","journal-title":"J. Orofac. Pain"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1111\/j.1365-2842.2011.02228.x","article-title":"Prevalence of self-reported symptoms related to temporomandibular disorders in an Italian population","volume":"38","author":"Mobilio","year":"2011","journal-title":"J. Oral. Rehabil."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1016\/S0140-6736(96)90280-9","article-title":"Does clicking in adolescence lead to painful temporomandibular joint locking?","volume":"347","author":"Waltimo","year":"1996","journal-title":"Lancet"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.oooo.2013.04.019","article-title":"Magnetic resonance imaging of temporomandibular joint dysfunction-correlation with clinical symptoms, age, and gender","volume":"116","author":"Lamot","year":"2013","journal-title":"Oral Surg. Oral Med. Oral Pathol. Oral Radiol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/j.joca.2016.12.028","article-title":"Frequency of temporomandibular joint osteoarthritis and related symptoms in a hand osteoarthritis cohort","volume":"25","author":"Abrahamsson","year":"2017","journal-title":"Osteoarthr. Cartil."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"67","DOI":"10.11607\/ofph.2374","article-title":"Cervical Muscle Tenderness in Temporomandibular Disorders and Its Associations with Diagnosis, Disease-Related Outcomes, and Comorbid Pain Conditions","volume":"34","author":"Almoznino","year":"2020","journal-title":"J. Oral Facial Pain Headache"},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Zieli\u0144ski, G., By\u015b, A., Szkutnik, J., Majcher, P., and Ginszt, M. (2021). Electromyographic Patterns of Masticatory Muscles in Relation to Active Myofascial Trigger Points of the Upper Trapezius and Temporomandibular Disorders. Diagnostics, 11.","DOI":"10.3390\/diagnostics11040580"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"37s","DOI":"10.1177\/0022034514528333","article-title":"TMJ Disc Displacement without Reduction Management: A Systematic Review","volume":"93","author":"Durham","year":"2014","journal-title":"J. Dent. Res."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"255","DOI":"10.4103\/2231-0746.175756","article-title":"Early magnetic resonance imaging control after temporomandibular joint arthrocentesis","volume":"5","author":"Sousa","year":"2015","journal-title":"Ann. Maxillofac. Surg."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"289","DOI":"10.3109\/00016357.2010.494621","article-title":"Risk factors associated with incidence and persistence of signs and symptoms of temporomandibular disorders","volume":"68","author":"Marklund","year":"2010","journal-title":"Acta Odontol. Scand."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1080\/00016350410001649","article-title":"Associations between social and general health factors and symptoms related to temporomandibular disorders and bruxism in a population of 50-year-old subjects","volume":"62","author":"Johansson","year":"2004","journal-title":"Acta Odontol. Scand."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1111\/joor.12685","article-title":"Prevalence of psychosocial impairment in temporomandibular disorder patients: A systematic review","volume":"45","author":"Conti","year":"2018","journal-title":"J. Oral. Rehabil."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"5641","DOI":"10.1007\/s00784-021-03866-z","article-title":"Patients referred to a German TMD-specialized consultation hour-a retrospective on patients without a diagnosis according to RDC\/TMD decision trees","volume":"25","author":"Rauch","year":"2021","journal-title":"Clin. Oral Investig."},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Zieli\u0144ski, G., Ginszt, M., Zawadka, M., Rutkowska, K., Podstawka, Z., Szkutnik, J., Majcher, P., and Gawda, P. (2021). The Relationship between Stress and Masticatory Muscle Activity in Female Students. J. Clin. Med., 10.","DOI":"10.3390\/jcm10163459"},{"key":"ref_29","first-page":"390","article-title":"Relationship between depression and masticatory muscles function in a group of adolescents","volume":"36","author":"Stocka","year":"2018","journal-title":"Cranio J. Craniomandib. Pract."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"720603","DOI":"10.1155\/2011\/720603","article-title":"Psychological Stress Induces Temporary Masticatory Muscle Mechanical Sensitivity in Rats","volume":"2011","author":"Huang","year":"2011","journal-title":"J. Biomed. Biotechnol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"273","DOI":"10.14219\/jada.archive.1990.0043","article-title":"Epidemiology of signs and symptoms in temporomandibular disorders: Clinical signs in cases and controls","volume":"120","author":"Dworkin","year":"1990","journal-title":"J. Am. Dent. Assoc."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1097\/AJP.0b013e31820215f5","article-title":"Temporomandibular disorders and associated clinical comorbidities","volume":"27","author":"Hoffmann","year":"2011","journal-title":"Clin. J. Pain"}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/12\/10\/3553\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:38:03Z","timestamp":1760125083000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/12\/10\/3553"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,18]]},"references-count":32,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2023,5]]}},"alternative-id":["jcm12103553"],"URL":"https:\/\/doi.org\/10.3390\/jcm12103553","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,18]]}}}