{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T18:18:00Z","timestamp":1788545880063,"version":"build-2803163510"},"reference-count":20,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T00:00:00Z","timestamp":1684972800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Even after a successful ventricular tachycardia ablation (VTA), some patients have recurrent ventricular tachycardia (VT) during their follow-up. We assessed the long-term predictors of recurrent VT after having a successful VTA. The patients who underwent a successful VTA (defined as the non-inducibility of any VT at the procedure\u2019s end) in 2014\u20132021 at our center in Israel were retrospectively analyzed. A total of 111 successful VTAs were evaluated. Out of them, 31 (27.9%) had a recurrent event of VT after the procedure during a median follow-up time of 264 days. The mean left ventricular ejection fraction (LVEF) was significantly lower among patients with recurrent VT events (28.9 \u00b1 12.67 vs. 23.53 \u00b1 12.224, p = 0.048). A high number of induced VTs (&gt;two) during the procedure was found to be a significant predictor of VT recurrence (24.69% vs. 56.67%, 20 vs. 17, p = 0.002). In a multivariate analysis, a lower LVEF (HR, 0.964; p = 0.037) and a high number of induced VTs (HR, 2.15; p = 0.039) were independent predictors of arrhythmia recurrence. The inducibility of more than two VTs during a VTA procedure remains a predictor of VT recurrence even after a successful VT ablation. This group of patients remains at high risk for VT and should be followed up with and treated more vigorously.<\/jats:p>","DOI":"10.3390\/jcm12113660","type":"journal-article","created":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T02:00:55Z","timestamp":1684980055000},"page":"3660","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Inducibility of Multiple Ventricular Tachycardia\u2019s during a Successful Ablation Procedure Is a Marker of Ventricular Tachycardia Recurrence"],"prefix":"10.3390","volume":"12","author":[{"given":"Johnatan","family":"Nissan","sequence":"first","affiliation":[{"name":"Department of Diagnostic Imaging, Sheba Medical Center, Ramat Gan 52621, Israel"},{"name":"Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avi","family":"Sabbag","sequence":"additional","affiliation":[{"name":"Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel"},{"name":"Davidai Arrhythmia Center, Leviev Heart Center, Sheba Medical Center, Ramat Gan 52621, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roy","family":"Beinart","sequence":"additional","affiliation":[{"name":"Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel"},{"name":"Davidai Arrhythmia Center, Leviev Heart Center, Sheba Medical Center, Ramat Gan 52621, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eyal","family":"Nof","sequence":"additional","affiliation":[{"name":"Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel"},{"name":"Davidai Arrhythmia Center, Leviev Heart Center, Sheba Medical Center, Ramat Gan 52621, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1161\/CIRCULATIONAHA.112.000872","article-title":"Management of Ventricular Tachycardia in the Setting of a Dedicated Unit for the Treatment of Complex Ventricular Arrhythmias: Long-Term Outcome after Ablation","volume":"127","author":"Baratto","year":"2013","journal-title":"Circulation"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1997","DOI":"10.1016\/j.hrthm.2015.05.036","article-title":"Freedom from Recurrent Ventricular Tachycardia after Catheter Ablation Is Associated with Improved Survival in Patients with Structural Heart Disease: An International VT Ablation Center Collaborative Group Study","volume":"12","author":"Tung","year":"2015","journal-title":"Heart Rhythm"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1161\/CIRCEP.113.001239","article-title":"Noninducibility and Late Potential Abolition: A Novel Combined Prognostic Procedural End Point for Catheter Ablation of Postinfarction Ventricular Tachycardia","volume":"7","author":"Silberbauer","year":"2014","journal-title":"Circ. Arrhythm. Electrophysiol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"e007045","DOI":"10.1161\/JAHA.117.007045","article-title":"Ablation Outcomes and Predictors of Mortality Following Catheter Ablation for Ventricular Tachycardia: Data from the German Multicenter Ablation Registry","volume":"7","author":"Tilz","year":"2018","journal-title":"J. Am. Heart Assoc."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1016\/j.ehj.2004.01.021","article-title":"Incidence and Significance of Pleomorphism in Patients with Postmyocardial Infarction Ventricular Tachycardia. Acute and Long-Term Outcome of Radiofrequency Catheter Ablation","volume":"25","author":"Riva","year":"2004","journal-title":"Eur. Heart J."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1093\/eurheartj\/ehaa612","article-title":"2020 ESC Guidelines for the Diagnosis and Management of Atrial Fibrillation Developed in Collaboration with the European Association for Cardio-Thoracic Surgery (EACTS)","volume":"42","author":"Hindricks","year":"2021","journal-title":"Eur. Heart J."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1161\/CIRCEP.113.001404","article-title":"Noninducibility in Postinfarction Ventricular Tachycardia as an End Point for Ventricular Tachycardia Ablation and Its Effects on Outcomes: A Meta-Analysis","volume":"7","author":"Ghanbari","year":"2014","journal-title":"Circ. Arrhythm. Electrophysiol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1080\/14017431.2019.1601253","article-title":"Long-Term Outcome of Catheter Ablation in Post-Infarction Recurrent Ventricular Tachycardia","volume":"53","author":"Haanschoten","year":"2019","journal-title":"Scand. Cardiovasc. J."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1161\/CIRCEP.114.002702","article-title":"Reassessing Noninducibility as Ablation Endpoint of Post-Infarction Ventricular Tachycardia","volume":"8","author":"Piers","year":"2015","journal-title":"Circ. Arrhythm. Electrophysiol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"e006730","DOI":"10.1161\/CIRCEP.118.006730","article-title":"Predictive Score for Identifying Survival and Recurrence Risk Profiles in Patients Undergoing Ventricular Tachycardia Ablation","volume":"11","author":"Vergara","year":"2018","journal-title":"Circ. Arrhythm. Electrophysiol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1161\/CIRCEP.113.000089","article-title":"Outcome of Ventricular Tachycardia Ablation in Patients with Nonischemic Cardiomyopathy","volume":"6","author":"Piers","year":"2013","journal-title":"Circ. Arrhythm. Electrophysiol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1111\/pace.14203","article-title":"The Prognostic Value of J-wave Pattern for Recurrence of Ventricular Tachycardia after Catheter Ablation in Patients with Myocardial Infarction","volume":"44","author":"Naruse","year":"2021","journal-title":"Pacing Clin. Electrophysiol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/j.hrthm.2021.02.016","article-title":"Ventricular Tachycardia Burden Reduction after Substrate Ablation: Predictors of Recurrence","volume":"18","author":"Quinto","year":"2021","journal-title":"Heart Rhythm"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1111\/j.1540-8167.2009.01705.x","article-title":"Influence of Clinical and Procedural Predictors on Ventricular Tachycardia Ablation Outcomes: An Analysis from the Substrate Mapping and Ablation in Sinus Rhythm to Halt Ventricular Tachycardia Trial (SMASH-VT)","volume":"21","author":"Tung","year":"2010","journal-title":"J. Cardiovasc. Electrophysiol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.hrthm.2019.10.017","article-title":"Direct and Indirect Mapping of Intramural Space in Ventricular Tachycardia","volume":"17","author":"Bhaskaran","year":"2020","journal-title":"Heart Rhythm"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s10840-021-01088-7","article-title":"Comparison of the Arrhythmogenic Substrate for Ventricular Tachycardia in Patients with Ischemic vs Non-Ischemic Cardiomyopathy\u2014Insights from High-Density, Multi-Electrode Catheter Mapping","volume":"66","author":"Kotake","year":"2023","journal-title":"J. Interv. Card. Electrophysiol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.ijcard.2018.08.099","article-title":"Ventricular Tachycardia Ablation in Structural Heart Disease: Impact of Ablation Strategy and Non-Inducibility as an End-Point on Long Term Outcome","volume":"277","author":"Breitenstein","year":"2019","journal-title":"Int. J. Cardiol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"e008307","DOI":"10.1161\/CIRCEP.119.008307","article-title":"Long-Term Outcome After Ventricular Tachycardia Ablation in Nonischemic Cardiomyopathy: Late Potential Abolition and VT Noninducibility","volume":"13","author":"Okubo","year":"2020","journal-title":"Circ. Arrhythm. Electrophysiol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1161\/CIRCEP.114.001929","article-title":"Re-Entry Using Anatomically Determined Isthmuses","volume":"8","author":"Kapel","year":"2015","journal-title":"Circ. Arrhythm. Electrophysiol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1111\/jce.12858","article-title":"VT Recurrence After Ablation: Incomplete Ablation or Disease Progression? A Multicentric European Study","volume":"27","author":"Berte","year":"2016","journal-title":"J. Cardiovasc. Electrophysiol."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/12\/11\/3660\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:41:39Z","timestamp":1760125299000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/12\/11\/3660"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,25]]},"references-count":20,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2023,6]]}},"alternative-id":["jcm12113660"],"URL":"https:\/\/doi.org\/10.3390\/jcm12113660","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,25]]}}}