{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T22:23:51Z","timestamp":1790029431762,"version":"4.0.1"},"reference-count":52,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2023,6,18]],"date-time":"2023-06-18T00:00:00Z","timestamp":1687046400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>MPOX (monkeypox) is a zoonotic viral disease, endemic in some Central and West African countries. However, in May 2022, cases began to be reported in non-endemic countries, demonstrating community transmission. Since the beginning of the outbreak, different epidemiological and clinical behaviors have been observed. We conducted an observational study at a secondary hospital in Madrid to characterize suspected and confirmed cases of MPOX epidemiologically and clinically. Besides the general descriptive analysis, we compared data between HIV-positive and HIV-negative subjects; 133 patients were evaluated with suspected MPOX, of which 100 were confirmed. Regarding positive cases, 71.0% were HIV positive, and 99.0% were men with a mean age of 33. In the previous year, 97.6% reported having sex with men, 53.6% used apps for sexual encounters, 22.9% practiced chemsex, and 16.7% went to saunas. Inguinal adenopathies were significantly higher in MPOX cases (54.0% vs. 12.1%, p &lt; 0.001), as the involvement of genital and perianal area (57.0% vs. 27.3% and 17.0% vs. 1.0%, p = 0.006 and p = 0.082 respectively). Pustules were the most common skin lesion (45.0%). In HIV-positive cases, only 6.9% had a detectable viral load, and the mean CD4 count was 607.0\/mm3. No significant differences were observed in the disease course, except for a greater tendency towards the appearance of perianal lesions. In conclusion, the MPOX 2022 outbreak in our area has been related to sexual intercourse among MSM, with no severe clinical cases nor apparent differences in HIV and non-HIV patients.<\/jats:p>","DOI":"10.3390\/jcm12124124","type":"journal-article","created":{"date-parts":[[2023,6,19]],"date-time":"2023-06-19T02:29:19Z","timestamp":1687141759000},"page":"4124","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Epidemiological and Clinical Characteristics of Patients Admitted to a Secondary Hospital with Suspected MPOX Virus Infection: Is HIV Playing a Role?"],"prefix":"10.3390","volume":"12","author":[{"given":"Samuel","family":"Est\u00e9vez","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Infanta Leonor University Hospital, 28031 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Vara","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine and Public Health, Infanta Leonor University Hospital, 28031 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"Gamo","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Infanta Leonor University Hospital, 28031 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Manzano","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Infanta Leonor University Hospital, 28031 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7323-114X","authenticated-orcid":false,"given":"Jes\u00fas","family":"Troya","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Infanta Leonor University Hospital, 28031 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ekaterina","family":"Botezat","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine and Public Health, Infanta Leonor University Hospital, 28031 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Jim\u00e9nez","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine and Public Health, Infanta Leonor University Hospital, 28031 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0318-2981","authenticated-orcid":false,"given":"Roberto","family":"Pedrero-Tom\u00e9","sequence":"additional","affiliation":[{"name":"Foundation for Biomedical Research and Innovation (FIIB), Infanta Leonor University Hospital, 28031 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda \u00c1ngeles","family":"Martin","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Infanta Leonor University Hospital, 28031 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"de la Cueva","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Infanta Leonor University Hospital, 28031 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Infanta Leonor University Hospital, 28031 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Infanta Leonor University Hospital, 28031 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David Esteban","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Infanta Leonor University Hospital, 28031 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Palma","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Infanta Leonor University Hospital, 28031 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Sim\u00f3n","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Infanta Leonor University Hospital, 28031 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,6,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Walter, K., and Malani, P.N. (JAMA, 2023). Update on Mpox, JAMA, epub ahead of print.","DOI":"10.1001\/jama.2023.9142"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/j.idc.2019.03.001","article-title":"Human Monkeypox","volume":"33","author":"Petersen","year":"2019","journal-title":"Infect. Dis. Clin. N. Am."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"772","DOI":"10.3390\/idr14050079","article-title":"Monkeypox: From A Neglected Tropical Disease to a Public Health Threat","volume":"14","author":"Antunes","year":"2022","journal-title":"Infect. Dis. Rep."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1136\/bmj.p1190","article-title":"WHO ends public health emergency designation for mpox","volume":"381","author":"Carlson","year":"2023","journal-title":"BMJ"},{"key":"ref_5","unstructured":"Ministerio de Sanidad de Espa\u00f1a (2023, April 20). Protocolo para la Detecci\u00f3n Precoz y Manejo de los Casos de Viruela de los Monos (Monkeypox) en Espa\u00f1a. Available online: https:\/\/www.sanidad.gob.es\/profesionales\/saludPublica\/ccayes\/alertasActual\/alertaMonkeypox\/docs\/ProtocoloMPX_20221102.pdf."},{"key":"ref_6","unstructured":"CDC (2023, April 25). Mpox in the U.S. Centers for Disease Control and Prevention, Available online: https:\/\/www.cdc.gov\/poxvirus\/mpox\/if-sick\/transmission.html."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/S0140-6736(22)01487-8","article-title":"Evidence of human-to-dog transmission of monkeypox virus","volume":"400","author":"Seang","year":"2022","journal-title":"Lancet"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1056\/NEJMra2208860","article-title":"Monkeypox","volume":"387","author":"Gessain","year":"2022","journal-title":"N. Engl. J. Med."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"e072410","DOI":"10.1136\/bmj-2022-072410","article-title":"Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: Descriptive case series","volume":"378","author":"Patel","year":"2022","journal-title":"BMJ"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1056\/NEJMoa2207323","article-title":"Monkeypox Virus Infection in Humans across 16 Countries\u2014April\u2013June 2022","volume":"387","author":"Thornhill","year":"2022","journal-title":"N. Engl. J. Med."},{"key":"ref_11","first-page":"e38083","article-title":"Making Sense of Monkeypox: A Comparison of Other Poxviruses to the Monkeypox","volume":"15","author":"Pattnaik","year":"2023","journal-title":"Cureus"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1177\/09564624221114191","article-title":"Monkeypox and HIV\/AIDS: When the outbreak faces the epidemic","volume":"33","year":"2022","journal-title":"Int. J. STD AIDS."},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Nyame, J., Punniyakotti, S., Khera, K., Pal, R.S., Varadarajan, N., and Sharma, P. (2023). Challenges in the treatment and prevention of Monkeypox infection; a comprehensive review. Acta Trop., 106960.","DOI":"10.1016\/j.actatropica.2023.106960"},{"key":"ref_14","unstructured":"Ministerio de Sanidad de Espa\u00f1a (2023, April 25). Actualizaci\u00f3n de las Recomendaciones de Vacunaci\u00f3n en el Brote de Viruela del Mono. Available online: https:\/\/www.sanidad.gob.es\/profesionales\/saludPublica\/prevPromocion\/vacunaciones\/MonkeyPox\/docs\/Estrategia_vacunacion_Monkeypox_07122022.pdf."},{"key":"ref_15","unstructured":"Monkeypox\u2014United Kingdom of Great Britain and Northern Ireland. World Health Organization (WHO) (2023, April 20). Available online: https:\/\/www.who.int\/emergencies\/disease-outbreak-news\/item\/2022-DON381."},{"key":"ref_16","unstructured":"(2023, April 20). Monkeypox\u2014United Kingdom of Great Britain and Northern Ireland. Available online: https:\/\/www.who.int\/emergencies\/disease-outbreak-news\/item\/2022-DON383."},{"key":"ref_17","unstructured":"European Centre for Disease Prevention and Control (2022). Monkeypox Multi-Country Outbreak\u201423 May 2022, ECDC."},{"key":"ref_18","unstructured":"(2023, April 20). Second Meeting of the International Health Regulations (2005) (IHR) Emergency Committee Regarding the Multi-Country Outbreak of Monkeypox. Available online: https:\/\/www.who.int\/news\/item\/23-07-2022-second-meeting-of-the-international-health-regulations-(2005)-(ihr)-emergency-committee-regarding-the-multi-country-outbreak-of-monkeypox."},{"key":"ref_19","unstructured":"World Health Organization (WHO) (2023, April 20). 2022\u201323 Mpox (Monkeypox) Outbreak: Global Trends, Available online: https:\/\/worldhealthorg.shinyapps.io\/mpx_global\/."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"2200497","DOI":"10.2807\/1560-7917.ES.2022.27.32.2200497","article-title":"Monkeypox: Another test for PCR","volume":"27","author":"Huggett","year":"2022","journal-title":"Euro Surveill."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research Electronic Data Capture (REDCap)\u2014A metadata-driven methodology and workflow process for providing translational research informatics support","volume":"42","author":"Harris","year":"2009","journal-title":"J. Biomed. Inform."},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Keikha, M., Kesharwani, P., and Sahebkar, A. (Microb. Pathog, 2023). Contradictory perspectives on the transmission route of human monkeypox during the 2022 outbreak, Microb. Pathog, epub ahead of print.","DOI":"10.1016\/j.micpath.2023.106178"},{"key":"ref_23","unstructured":"Ministerio de Sanidad de Espa\u00f1a (2023, April 24). Situaci\u00f3n Epidemiol\u00f3gica de los Casos de Viruela del Mono. Datos Extra\u00eddos de SiViES el 18\/04\/2023. Available online: https:\/\/www.isciii.es\/QueHacemos\/Servicios\/VigilanciaSaludPublicaRENAVE\/EnfermedadesTransmisibles\/Documents\/archivos%20A-Z\/MPOX\/SITUACION%20EPIDEMIOLOGICA%20DE%20LOS%20CASOS%20DE%20VIRUELA%20DEL%20MONO-18042023.pdf."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/S1473-3099(22)00651-X","article-title":"Epidemiological and clinical characteristics of patients with monkeypox in the GeoSentinel Network: A cross-sectional study","volume":"23","author":"Angelo","year":"2023","journal-title":"Lancet Infect. Dis."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"e073153","DOI":"10.1136\/bmj-2022-073153","article-title":"Transmission dynamics of monkeypox in the United Kingdom: Contact tracing study","volume":"379","author":"Ward","year":"2022","journal-title":"BMJ"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"2409","DOI":"10.3201\/eid2812.221440","article-title":"Observational Cohort Study of Evolving Epidemiologic, Clinical, and Virologic Features of Monkeypox in Southern France","volume":"28","author":"Cassir","year":"2022","journal-title":"Emerg. Infect. Dis."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.cmi.2022.08.012","article-title":"Clinical characteristics of ambulatory and hospitalized patients with monkeypox virus infection: An observational cohort study","volume":"29","author":"Mailhe","year":"2023","journal-title":"Clin. Microbiol. Infect."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.3201\/eid2809.221051","article-title":"Epidemiologic Features and Control Measures during Monkeypox Outbreak, Spain, June 2022","volume":"28","author":"Castrillejo","year":"2022","journal-title":"Emerg. Infect. Dis."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1111\/bjd.21790","article-title":"Monkeypox outbreak in Spain: Clinical and epidemiological findings in a prospective cross-sectional study of 185 cases","volume":"187","year":"2022","journal-title":"Br. J. Dermatol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1016\/S1473-3099(22)00411-X","article-title":"Demographic and clinical characteristics of confirmed human monkeypox virus cases in individuals attending a sexual health centre in London, UK: An observational analysis","volume":"22","author":"Girometti","year":"2022","journal-title":"Lancet Infect. Dis."},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Liu, Q., Fu, L., Wang, B., Sun, Y., Wu, X., Peng, X., Li, Y., Lin, Y.-F., Fitzpatrick, T., and Vermund, S.H. (2023). Clinical Characteristics of Human Mpox (Monkeypox) in 2022: A Systematic Review and Meta-Analysis. Pathogens, 12.","DOI":"10.3390\/pathogens12010146"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/S0140-6736(22)01436-2","article-title":"Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain: A prospective observational cohort study","volume":"400","author":"Alemany","year":"2022","journal-title":"Lancet"},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Siegenbeek van Heukelom, M.L., Jongen, V.W., Schouten, J., Hoornenborg, E., Bruisten, S., Westerhuis, B., Welkers, M.R., Vergunst, C.E., Prins, M., and van der Loeff, M.F.S. (2023). Characteristics of mpox positive, versus mpox negative, and mpox unsuspected clients from the Centre of Sexual Health, Public Health Service of Amsterdam, 20 May to 15 September 2022. J. Eur. Acad Dermatol. Venereol.","DOI":"10.1111\/jdv.19223"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"e28230","DOI":"10.1002\/jmv.28230","article-title":"A systematic review and clinical atlas on mucocutaneous presentations of the current monkeypox outbreak: With a comprehensive approach to all dermatologic and nondermatologic aspects of the new and previous monkeypox outbreaks","volume":"95","author":"Pourriyahi","year":"2023","journal-title":"J. Med. Virol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1016\/j.jaad.2022.12.035","article-title":"A dermatologic assessment of 101 mpox (monkeypox) cases from 13 countries during the 2022 outbreak: Skin lesion morphology, clinical course, and scarring","volume":"88","author":"Prasad","year":"2023","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"2200421","DOI":"10.2807\/1560-7917.ES.2022.27.22.2200421","article-title":"Epidemiological, clinical and virological characteristics of four cases of monkeypox support transmission through sexual contact, Italy, May 2022","volume":"27","author":"Antinori","year":"2022","journal-title":"Eurosurveillance"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"e210","DOI":"10.1093\/cid\/ciaa143","article-title":"Clinical Course and Outcome of Human Monkeypox in Nigeria","volume":"71","author":"Ogoina","year":"2020","journal-title":"Clin. Infect. Dis."},{"key":"ref_38","doi-asserted-by":"crossref","unstructured":"Gamo Guerrero, M., Sim\u00f3n Gozalbo, A., Mart\u00edn D\u00edaz, M.A., Diez Madue\u00f1o, K., Del Rio Pena, E., De la Cueva Dobao, P., Talav\u00e1n, T., Jim\u00e9nez, E., Torres-Macho, J., and Valencia, J. (Front. Med., 2023). Interdisciplinary management of MPOX-related local complications: Report on a series of cases, Front. Med., submitted.","DOI":"10.3389\/fmed.2023.1184924"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s12245-023-00491-3","article-title":"Monkeypox epidemiology, clinical presentation, and transmission: A systematic review","volume":"16","author":"Sharma","year":"2023","journal-title":"Int. J. Emerg. Med."},{"key":"ref_40","unstructured":"Philpott, D. (2022). Epidemiologic and Clinical Characteristics of Monkeypox Cases\u2014United States, 17 May\u201322 July 2022. MMWR Morb. Mortal. Wkly. Rep., Available online: https:\/\/www.cdc.gov\/mmwr\/volumes\/71\/wr\/mm7132e3.htm."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/j.jaad.2022.08.048","article-title":"Monkeypox: Cutaneous clues to clinical diagnosis","volume":"88","author":"Frew","year":"2023","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_42","unstructured":"(2023, April 20). Joint ECDC-WHO Regional Office for Europe Mpox Surveillance Bulletin. Available online: https:\/\/monkeypoxreport.ecdc.europa.eu\/."},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Ortiz-Saavedra, B., Montes-Madariaga, E.S., Cabanillas-Ramirez, C., Alva, N., Ricardo-Mart\u00ednez, A., Le\u00f3n-Figueroa, D.A., Barboza, J.J., Mohanty, A., Padhi, B.K., and Sah, R. (2023). Epidemiologic Situation of HIV and Monkeypox Coinfection: A Systematic Review. Vaccines, 11.","DOI":"10.3390\/vaccines11020246"},{"key":"ref_44","unstructured":"(2023, April 20). Direcci\u00f3n General de Salud P\u00fablica Sistemas Auton\u00f3micos de Vigilancia Epidemiol\u00f3gica. Vigilancia Epidemiol\u00f3gica del VIH y SIDA en Espa\u00f1a 2021. Actualizaci\u00f3n 30 de Junio de 2022. Available online: https:\/\/www.isciii.es\/QueHacemos\/Servicios\/VigilanciaSaludPublicaRENAVE\/EnfermedadesTransmisibles\/Documents\/VIH\/informes%20de%20vigilancia%20VIH%20y%20sida%20anteriores\/Informe%20VIH_SIDA_2022_CCAA.pdf."},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Wang, X., and Lun, W. (2023). Skin Manifestation of Human Monkeypox. J. Clin. Med., 12.","DOI":"10.3390\/jcm12030914"},{"key":"ref_46","doi-asserted-by":"crossref","unstructured":"Tiecco, G., Degli Antoni, M., Storti, S., Tomasoni, L.R., Castelli, F., and Quiros-Roldan, E. (2022). Monkeypox, a Literature Review: What Is New and Where Does This concerning Virus Come From?. Viruses, 14.","DOI":"10.3390\/v14091894"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1016\/S1473-3099(19)30294-4","article-title":"Outbreak of human monkeypox in Nigeria in 2017\u20132018: A clinical and epidemiological report","volume":"19","author":"Aruna","year":"2019","journal-title":"Lancet Infect. Dis."},{"key":"ref_48","doi-asserted-by":"crossref","unstructured":"Mills, E.J., Nachega, J.B., Bangsberg, D.R., Singh, S., Rachlis, B., Wu, P., Wilson, K., Buchan, I., Gill, C.J., and Cooper, C. (2006). Adherence to HAART: A Systematic Review of Developed and Developing Nation Patient-Reported Barriers and Facilitators. PLoS Med., 3.","DOI":"10.1371\/journal.pmed.0030438"},{"key":"ref_49","unstructured":"Curran, K.G. (2022). HIV and Sexually Transmitted Infections among Persons with Monkeypox\u2014Eight. U.S. Jurisdictions, 17 May\u201322 July 2022. MMWR Morb. Mortal. Wkly. Rep., Available online: https:\/\/www.cdc.gov\/mmwr\/volumes\/71\/wr\/mm7136a1.htm."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1038\/s41577-022-00775-4","article-title":"Monkeypox: Disease epidemiology, host immunity and clinical interventions","volume":"22","author":"Lum","year":"2022","journal-title":"Nat. Rev. Immunol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"e349","DOI":"10.1016\/S1473-3099(22)00574-6","article-title":"Prevention of monkeypox with vaccines: A rapid review","volume":"22","author":"Poland","year":"2022","journal-title":"Lancet Infect. Dis."},{"key":"ref_52","doi-asserted-by":"crossref","unstructured":"Malone, S.M., Mitra, A.K., Onumah, N.A., Brown, A., Jones, L.M., Tresvant, D., Brown, C.S., Onyia, A.U., and Iseguede, F.O. (2023). Safety and Efficacy of Post-Eradication Smallpox Vaccine as an Mpox Vaccine: A Systematic Review with Meta-Analysis. Int. J. Environ. Res. Public Health, 20.","DOI":"10.3390\/ijerph20042963"}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/12\/12\/4124\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:56:02Z","timestamp":1760126162000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/12\/12\/4124"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,18]]},"references-count":52,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2023,6]]}},"alternative-id":["jcm12124124"],"URL":"https:\/\/doi.org\/10.3390\/jcm12124124","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,18]]}}}