{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T09:43:10Z","timestamp":1769938990615,"version":"3.49.0"},"reference-count":81,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2023,6,22]],"date-time":"2023-06-22T00:00:00Z","timestamp":1687392000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Irritable bowel syndrome (IBS) is a disorder of the gut\u2013brain interaction (DGBI), characterized, mainly in severe cases, by altered psychological stress reactivity, psychological disorders, and dysfunction of the brain\u2013gut\u2013microbiota axis. Prior studies have highlighted significant physical and emotional impairments in the health-related quality of life of patients with IBS. Resilience is a psychosocial ability that reduces negative emotions while enhancing adaptation to adversities. Resilience is essential for health promotion and stress response. The present study aimed to carry out a review of the literature in multiple databases, using the descriptors \u201cresilience\u201d, \u201cresiliency\u201d, and \u201cirritable bowel syndrome\u201d. The inclusion criteria for obtaining the most relevant papers were research articles on resilience and irritable bowel syndrome written in English, published in a peer-reviewed journal, and involving human subjects. Studies specifically on resilience in IBS were sparse. These results need to be understood in light of these limitations. As resilience appears to be modifiable, it is essential to conduct direct research on resilience-enhancing interventions for people with IBS. The study of the factors involved in successful adaptation must be extended, to possibly yield new interventions that help the patients overcome the difficulties imposed by the disease.<\/jats:p>","DOI":"10.3390\/jcm12134220","type":"journal-article","created":{"date-parts":[[2023,6,23]],"date-time":"2023-06-23T02:34:07Z","timestamp":1687487647000},"page":"4220","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Irritable Bowel Syndrome and Resilience"],"prefix":"10.3390","volume":"12","author":[{"given":"Mihaela","family":"Fadgyas Stanculete","sequence":"first","affiliation":[{"name":"Department of Neurosciences, \u201cIuliu Hatieganu\u201d University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7435-271X","authenticated-orcid":false,"given":"Abdulrahman","family":"Ismaiel","sequence":"additional","affiliation":[{"name":"2nd Department of Internal Medicine, \u201cIuliu Hatieganu\u201d University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5508-2598","authenticated-orcid":false,"given":"Stefan-Lucian","family":"Popa","sequence":"additional","affiliation":[{"name":"2nd Department of Internal Medicine, \u201cIuliu Hatieganu\u201d University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Octavia Oana","family":"Capatina","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, \u201cIuliu Hatieganu\u201d University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,6,22]]},"reference":[{"key":"ref_1","first-page":"1","article-title":"A critical review of resilience theory and its relevance for social work","volume":"54","year":"2018","journal-title":"Soc. Work"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1300\/J137v08n04_05","article-title":"Resilience theory: Theoretical and professional conceptualizations","volume":"8","author":"Greene","year":"2004","journal-title":"J. Hum. Behav. Soc. Environ."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1111\/jftr.12255","article-title":"Resilience theory and research on children and families: Past, present, and promise","volume":"10","author":"Masten","year":"2018","journal-title":"J. Fam. Theory Rev."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1177\/070674371105600504","article-title":"What is resilience?","volume":"56","author":"Herrman","year":"2011","journal-title":"Can. J. Psychiatry"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1037\/0735-7028.36.3.230","article-title":"Assessing strengths, resilience, and growth to guide clinical interventions","volume":"36","author":"Tedeschi","year":"2005","journal-title":"Prof. Psychol. Res. Pract."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"2295","DOI":"10.1016\/j.childyouth.2012.08.009","article-title":"Resilience in children and youth: A review","volume":"3","author":"Zolkoski","year":"2012","journal-title":"Child. Youth Serv. Rev."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1177\/1473325009337840","article-title":"Understanding marginal perspectives: Towards a social theory of resilience","volume":"8","author":"Bottrell","year":"2009","journal-title":"Qual. Soc. Work"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.cpr.2010.03.003","article-title":"Resilience and mental health","volume":"30","author":"Davydov","year":"2010","journal-title":"Clin. Psychol. Rev."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.paid.2014.11.039","article-title":"A meta-analysis of the trait resilience and mental health","volume":"76","author":"Hu","year":"2015","journal-title":"Personal. Individ. Differ."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1002\/per.2410010304","article-title":"Transactional theory and research on emotions and coping","volume":"1","author":"Lazarus","year":"1987","journal-title":"Eur. J. Personal."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"e92","DOI":"10.1017\/S0140525X1400082X","article-title":"A conceptual framework for the neurobiological study of resilience","volume":"38","author":"Kalisch","year":"2015","journal-title":"Behav. Brain Sci."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/acps.12095","article-title":"Resilience in mental health: Linking psychological and neurobiological perspectives","volume":"128","author":"Rutten","year":"2013","journal-title":"Acta Psychiatr. Scand."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.amjsurg.2014.05.016","article-title":"Psychological factors predicting outcome after traumatic injury: The role of resilience","volume":"8","author":"Rainey","year":"2014","journal-title":"Am. J. Surg."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/S0145-2134(00)00141-1","article-title":"Resilience factors in the victims of sexual abuse: State of affairs","volume":"24","author":"Dufour","year":"2000","journal-title":"Child Abus. Negl."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1016\/j.jpain.2017.04.009","article-title":"Beyond negative pain-related psychological factors: Resilience is related to lower pain affect in healthy adults","volume":"18","author":"Hemington","year":"2017","journal-title":"J. Pain"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1037\/a0019061","article-title":"Personal social networks and health: Conceptual and clinical implications of their reciprocal impact","volume":"28","author":"Sluzki","year":"2010","journal-title":"Fam. Syst. Health"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"S100","DOI":"10.1016\/j.eurpsy.2017.01.311","article-title":"Resilient coping and social networks in old age","volume":"41","author":"Daniel","year":"2017","journal-title":"Eur. Psychiatry"},{"key":"ref_18","first-page":"690","article-title":"Social support and social networks in COPD: A scoping review","volume":"12","author":"Barton","year":"2015","journal-title":"COPD J. Chronic Obstr. Pulm. Dis."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1002\/smi.1258","article-title":"A person-focused analysis of resilience resources and coping in patients with diabetes","volume":"26","author":"Smith","year":"2010","journal-title":"Stress Health"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1177\/070674371105600505","article-title":"Resilience following child maltreatment: A review of protective factors","volume":"56","author":"Afifi","year":"2011","journal-title":"Can. J. Psychiatry"},{"key":"ref_21","first-page":"131","article-title":"Strategies to promote coping and resilience in oncology and palliative care nurses caring for adult patients with malignancy: A comprehensive systematic review","volume":"13","author":"Gillman","year":"2015","journal-title":"JBI Evid. Synth."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1080\/10705500802222972","article-title":"The brief resilience scale: Assessing the ability to bounce back","volume":"15","author":"Smith","year":"2008","journal-title":"Int. J. Behav. Med."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1001\/jama.2020.22532","article-title":"Diagnosis and Treatment of Irritable Bowel Syndrome: A Review","volume":"325","author":"Camilleri","year":"2021","journal-title":"JAMA"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.mcna.2018.08.006","article-title":"Irritable Bowel Syndrome: What Treatments Really Work","volume":"103","author":"Alammar","year":"2019","journal-title":"Med. Clin. N. Am."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"14126","DOI":"10.3748\/wjg.v20.i39.14126","article-title":"Impact of psychological stress on irritable bowel syndrome","volume":"20","author":"Qin","year":"2014","journal-title":"World J. Gastroenterol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1007\/s00406-014-0502-z","article-title":"Anxiety and depression comorbidities in irritable bowel syndrome (IBS): A systematic review and meta-analysis","volume":"264","author":"Fond","year":"2014","journal-title":"Eur. Arch. Psychiatry Clin. Neurosci."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"104033","DOI":"10.1016\/j.brat.2022.104033","article-title":"Cognitive flexibility improves in cognitive behavioral therapy for irritable bowel syndrome but not nonspecific education\/support","volume":"154","author":"Lackner","year":"2022","journal-title":"Behav. Res. Ther."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.neulet.2017.09.049","article-title":"New tools for understanding coping and resilience","volume":"693","author":"Baratta","year":"2019","journal-title":"Neurosci. Lett."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1177\/1049909119893977","article-title":"Resilience in Caregivers: A Systematic Review","volume":"37","author":"Palacio","year":"2020","journal-title":"Am. J. Hosp. Palliat. Med."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1080\/10401334.2016.1146611","article-title":"Resilience Among Medical Students: The Role of Coping Style and Social Support","volume":"28","author":"Thompson","year":"2016","journal-title":"Teach. Learn. Med."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1097\/HRP.0000000000000194","article-title":"Understanding Resilience and Preventing and Treating PTSD","volume":"26","author":"Horn","year":"2018","journal-title":"Harv. Rev. Psychiatry"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"632141","DOI":"10.3389\/fnagi.2021.632141","article-title":"Resilience and Psychobiological Response to Stress in Older People: The Mediating Role of Coping Strategies","volume":"13","author":"Pulopulos","year":"2021","journal-title":"Front. Aging Neurosci."},{"key":"ref_33","first-page":"RA55","article-title":"Irritable bowel syndrome: A model of the brain-gut interactions","volume":"10","author":"Mulak","year":"2004","journal-title":"Med. Sci. Monit. Int. Med. J. Exp. Clin. Res."},{"key":"ref_34","first-page":"98","article-title":"Biopsychosocial approach of gastrointestinal disorders","volume":"87","author":"Pojoga","year":"2014","journal-title":"Clujul Med."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1053\/j.gastro.2005.11.033","article-title":"Hypothalamic-pituitary-gut axis dysregulation in irritable bowel syndrome: Plasma cytokines as a potential biomarker?","volume":"130","author":"Shanahan","year":"2006","journal-title":"Gastroenterology"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1016\/j.clinthera.2015.04.002","article-title":"Gut-Microbiota-Brain Axis and Its Effect on Neuropsychiatric Disorders with Suspected Immune Dysregulation","volume":"37","author":"Petra","year":"2015","journal-title":"Clin. Ther."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1038\/ajg.2011.377","article-title":"Gastrointestinal and psychological mediators of health-related quality of life in IBS and IBD: A structural equation modeling analysis","volume":"107","author":"Naliboff","year":"2012","journal-title":"Am. J. Gastroenterol."},{"key":"ref_38","first-page":"111","article-title":"Coping strategies and dysfunctional cognitions as predictors of irritable bowel syndrome diagnosis","volume":"15","author":"Dumitrascu","year":"2015","journal-title":"J. Evid.-Based Psychother."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S0022-3999(01)00207-0","article-title":"Gender differences in psychological distress among patients with irritable bowel syndrome","volume":"50","author":"Blanchard","year":"2001","journal-title":"J. Psychosom. Res."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1111\/j.1365-2036.2008.03847.x","article-title":"Irritable bowel syndrome and dyspepsia among women veterans: Prevalence and association with psychological distress","volume":"1","author":"Savas","year":"2009","journal-title":"Aliment. Pharmacol. Ther."},{"key":"ref_41","first-page":"165","article-title":"Development and psychometric evaluation of the resilience scale","volume":"1","author":"Wagnild","year":"1993","journal-title":"J. Nurs. Meas."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1080\/07481180701603246","article-title":"The role of dispositional resilience in regaining life satisfaction after the loss of a spouse","volume":"31","author":"Rossi","year":"2007","journal-title":"Death Stud."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1080\/00207594.2012.729840","article-title":"The role of psychological resilience and positive affect in risky decision-making","volume":"48","author":"Xing","year":"2013","journal-title":"Int. J. Psychol."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"32","DOI":"10.3109\/13685530903296698","article-title":"Life satisfaction, anxiety, depression and resilience across the life span of men","volume":"13","author":"Beutel","year":"2010","journal-title":"Aging Male"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1080\/13548506.2016.1168932","article-title":"Relations between symptom severity, illness perceptions, visceral sensitivity, coping strategies and well-being in irritable bowel syndrome guided by the common sense model of illness","volume":"22","author":"Knowles","year":"2017","journal-title":"Psychol. Health Med."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.genhosppsych.2003.07.005","article-title":"Social learning, affective state and passive coping in irritable bowel syndrome and inflammatory bowel disease","volume":"26","author":"Crane","year":"2004","journal-title":"Gen. Hosp. Psychiatry"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.jpsychores.2013.08.002","article-title":"Psychosocial predictors of irritable bowel syndrome diagnosis and symptom severity","volume":"75","author":"Phillips","year":"2013","journal-title":"J. Psychosom. Res."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"6402","DOI":"10.3748\/wjg.v22.i28.6402","article-title":"Personality traits and emotional patterns in irritable bowel syndrome","volume":"22","author":"Muscatello","year":"2016","journal-title":"World J. Gastroenterol."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"e12535","DOI":"10.1111\/ijn.12535","article-title":"The influence of resilience on mental health: The role of general well-being","volume":"3","author":"Gao","year":"2017","journal-title":"Int. J. Nurs. Pract."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1136\/gutjnl-2020-321191","article-title":"Efficacy of psychological therapies for irritable bowel syndrome: Systematic review and network meta-analysis","volume":"69","author":"Black","year":"2020","journal-title":"Gut"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"e14531","DOI":"10.1111\/nmo.14531","article-title":"Positive psychological well-being: A novel concept for improving symptoms, quality of life, and health behaviors in irritable bowel syndrome","volume":"35","author":"Madva","year":"2023","journal-title":"Neurogastroenterol. Motil."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1080\/10615806.2020.1772969","article-title":"Coping and resilience in adults: A cross-sectional network analysis","volume":"33","author":"Jongerling","year":"2020","journal-title":"Anxiety Stress Coping"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1177\/1049732302238251","article-title":"Appraising the evidence: Reviewing disparate data systematically","volume":"12","author":"Hawker","year":"2002","journal-title":"Qual. Health Res."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1097\/SGA.0000000000000011","article-title":"The importance of a person-centered approach in diagnostic workups of patients with irritable bowel syndrome: A qualitative study","volume":"36","author":"Ringstrom","year":"2013","journal-title":"Gastroenterol. Nurs."},{"key":"ref_55","doi-asserted-by":"crossref","unstructured":"Fischer, S., Lemmer, G., Gollwitzer, M., and Nater, U.M. (2014). Stress and resilience in functional somatic syndromes\u2014A structural equation modeling approach. PLoS ONE, 9.","DOI":"10.1371\/journal.pone.0111214"},{"key":"ref_56","doi-asserted-by":"crossref","unstructured":"Kuo, B., Bhasin, M., Jacquart, J., Scult, M.A., Slipp, L., Riklin, E.I., Lepoutre, V., Comosa, N., Norton, B.A., and Dassatti, A. (2015). Genomic and clinical effects associated with a relaxation response mind-body intervention in patients with irritable bowel syndrome and inflammatory bowel disease. PLoS ONE, 10.","DOI":"10.1371\/journal.pone.0123861"},{"key":"ref_57","first-page":"561","article-title":"The role of positive personality traits in emotion regulation of patients with irritable bowel syndrome (IBS)","volume":"44","author":"Mazaheri","year":"2015","journal-title":"Iran. J. Public Health"},{"key":"ref_58","first-page":"54","article-title":"Cognitive appraisal and psychological distress among patients with irritable bowel syndrome","volume":"52","author":"Palgi","year":"2015","journal-title":"Isr. J. Psychiatry Relat. Sci."},{"key":"ref_59","first-page":"e5809","article-title":"Efficacy of dialectical behavior therapy on stress, resilience and coping strategies in irritable bowel syndrome patients","volume":"19","author":"Adibi","year":"2017","journal-title":"Zahedan J. Res. Med. Sci."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"e13155","DOI":"10.1111\/nmo.13155","article-title":"Resilience is decreased in irritable bowel syndrome and is associated with symptoms and cortisol response","volume":"30","author":"Park","year":"2018","journal-title":"Neurogastroenterol. Motil."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"105","DOI":"10.5455\/msm.2017.29.105-108","article-title":"Comparison of resilience and psychological wellbeing in women with irritable bowel syndrome and normal women","volume":"29","author":"Shahdadi","year":"2017","journal-title":"Mater. Socio-Med."},{"key":"ref_62","doi-asserted-by":"crossref","unstructured":"Peter, J., Tran, U.S., Michalski, M., and Moser, G. (2018). The structure of resilience in irritable bowel syndrome and its improvement through hypnotherapy: Cross-sectional and prospective longitudinal data. PLoS ONE, 13.","DOI":"10.1371\/journal.pone.0202538"},{"key":"ref_63","first-page":"29","article-title":"Effect of selected personality traits and stress on symptoms of irritable bowel syndrome","volume":"60","author":"Mach","year":"2020","journal-title":"Folia Med. Crac."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"2541","DOI":"10.1016\/j.cgh.2020.08.043","article-title":"The Role of Resilience in Irritable Bowel Syndrome, Other Chronic Gastrointestinal Conditions, and the General Population","volume":"19","author":"Parker","year":"2020","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"ref_65","first-page":"A7","article-title":"Guidance on the conduct of narrative synthesis in systematic reviews. A product from the ESRC methods programme","volume":"59","author":"Popay","year":"2005","journal-title":"J. Epidemiol. Community Health"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"115","DOI":"10.2147\/NDT.S179013","article-title":"Frequent attenders in general medical practice in Italy: A preliminary report on clinical variables related to low functioning","volume":"15","author":"Carmassi","year":"2018","journal-title":"Neuropsychiatr. Dis. Treat."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/j.dld.2005.06.011","article-title":"The general practitioner\u2019s approach to irritable bowel syndrome: From intention to practice","volume":"37","author":"Bellini","year":"2005","journal-title":"Dig. Liver Dis."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"5089","DOI":"10.3748\/wjg.v17.i46.5089","article-title":"Evaluation of latent links between irritable bowel syndrome and sleep quality","volume":"17","author":"Bellini","year":"2011","journal-title":"World J. Gastroenterol."},{"key":"ref_69","doi-asserted-by":"crossref","unstructured":"Grover, M., Kolla, B.P., Pamarthy, R., Mansukhani, M.P., Breen-Lyles, M., He, J.P., and Merikangas, K.R. (2021). Psychological, physical, and sleep comorbidities and functional impairment in irritable bowel syndrome: Results from a national survey of U.S. adults. PLoS ONE, 16.","DOI":"10.1371\/journal.pone.0245323"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1093\/abm\/kaaa048","article-title":"The Relationship Between Coping Strategies and Sleep Problems: The Role of Depressive Symptoms","volume":"55","author":"Kozusznik","year":"2021","journal-title":"Ann. Behav. Med."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1053\/j.gastro.2016.02.027","article-title":"Biopsychosocial aspects of functional gastrointestinal disorders: How central and environmental processes contribute to the development and expression of functional gastrointestinal disorders","volume":"150","author":"Levy","year":"2016","journal-title":"Gastroenterology"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1038\/nn.3234","article-title":"Neurobiology of resilience","volume":"15","author":"Russo","year":"2012","journal-title":"Nat. Neurosci."},{"key":"ref_73","doi-asserted-by":"crossref","unstructured":"Bear, T., Dalziel, J., Coad, J., Roy, N., Butts, C., and Gopal, P. (2021). The Microbiome-Gut-Brain Axis and Resilience to Developing Anxiety or Depression under Stress. Microorganisms, 9.","DOI":"10.3390\/microorganisms9040723"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"43859","DOI":"10.1038\/srep43859","article-title":"Microbiota alteration is associated with the development of stress-induced despair behavior","volume":"7","author":"Marin","year":"2017","journal-title":"Sci. Rep."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.bbi.2018.08.010","article-title":"Resilience and immunity","volume":"74","author":"Dantzer","year":"2018","journal-title":"Brain Behav. Immun."},{"key":"ref_76","doi-asserted-by":"crossref","unstructured":"Zhou, K., Ning, F., Wang, W., and Li, X. (2022). The mediator role of resilience between psychological predictors and health-related quality of life in breast cancer survivors: A cross-sectional study. BMC Cancer, 22.","DOI":"10.1186\/s12885-022-09177-0"},{"key":"ref_77","first-page":"79","article-title":"Resilience in Chronic Disease","volume":"13","author":"Ye","year":"2022","journal-title":"Front. Psychol."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1002\/pon.5668","article-title":"Resilience patterns and transitions in the be resilient to breast cancer trial: An exploratory latent profile transition analysis","volume":"30","author":"Ye","year":"2021","journal-title":"Psycho-Oncology"},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.gtc.2022.07.001","article-title":"Stress, Resilience, and the Brain\u2013Gut Axis: Why is Psychogastroenterology Important for all Digestive Disorders?","volume":"51","author":"Ballou","year":"2022","journal-title":"Gastroenterol. Clin."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1097\/MCG.0000000000001234","article-title":"Recent advances in cognitive behavioral therapy for digestive disorders and the role of applied positive psychology across the spectrum of GI care","volume":"53","author":"Feingold","year":"2019","journal-title":"J. Clin. Gastroenterol."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1038\/s41575-018-0001-1","article-title":"Behavioural medicine and gastrointestinal disorders: The promise of positive psychology","volume":"15","author":"Keefer","year":"2018","journal-title":"Nat. Rev. Gastroenterol. Hepatol."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/12\/13\/4220\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:58:49Z","timestamp":1760126329000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/12\/13\/4220"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,22]]},"references-count":81,"journal-issue":{"issue":"13","published-online":{"date-parts":[[2023,7]]}},"alternative-id":["jcm12134220"],"URL":"https:\/\/doi.org\/10.3390\/jcm12134220","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,22]]}}}