{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T15:59:09Z","timestamp":1765727949320,"version":"build-2065373602"},"reference-count":30,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2023,6,27]],"date-time":"2023-06-27T00:00:00Z","timestamp":1687824000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Associa\u00e7\u00e3o Hospitalar de Prote\u00e7\u00e3o \u00e0 Inf\u00e2ncia Dr. Raul Carneiro"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: The coronavirus disease 2019 (COVID-19) pandemic began in Brazil on 26 February 2020. By 6 May 2023, 37.4 million cases had been confirmed, causing 701 thousand deaths in the country. We aimed to describe the epidemiological profile and clinical development of COVID-19 cases among the employees of a health institution, from acute infection to long COVID. Methods: This was a longitudinal study using a retrospective and prospective approach via questionnaires referring to epidemiological investigation, which was the inclusion criteria, and about long-term symptoms. Results: A total of 809 employees were detected with SARS-CoV-2 infection via RT-PCR, 466 of them answered the epidemiological investigation, and 101 completed the Long COVID Symptom Questionnaire. The most commonly affected employees were women (88.6%) working in patient care (68.6%). Headache, myalgia, cough, odynophagia, and runny nose were the most frequent symptoms. Only three employees (0.6%) required hospitalization, while the other employees required outpatient management due to mild symptoms. We identified 19 (4.1%) cases of reinfection, and 42 (41.6%) employees reported long-term symptoms, such as myalgia, dyspnea, and headache. Conclusions: Although most cases were mild with good outcomes, long COVID cases identified are noteworthy, as these symptoms may impact quality of life even months after SARS-CoV-2 infection.<\/jats:p>","DOI":"10.3390\/jcm12134325","type":"journal-article","created":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T00:45:11Z","timestamp":1687913111000},"page":"4325","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["From Acute Phase to Long COVID: A Cross-Sectional Study of the Epidemiological Profile and Clinical Evaluation of SARS-CoV-2 Infection in Employees at a Pediatric Hospital"],"prefix":"10.3390","volume":"12","author":[{"given":"Marielen Ribeiro Tavares","family":"da Silva","sequence":"first","affiliation":[{"name":"Faculdades Pequeno Pr\u00edncipe, Curitiba 80230-020, PR, Brazil"},{"name":"Instituto de Pesquisa Pel\u00e9 Pr\u00edncipe, Curitiba 80250-060, PR, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Paula","family":"Costa","sequence":"additional","affiliation":[{"name":"Hospital Pequeno Pr\u00edncipe, Curitiba 80250-060, PR, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda Almeida","family":"da Luz","sequence":"additional","affiliation":[{"name":"Faculdades Pequeno Pr\u00edncipe, Curitiba 80230-020, PR, Brazil"},{"name":"Instituto de Pesquisa Pel\u00e9 Pr\u00edncipe, Curitiba 80250-060, PR, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-7108-5335","authenticated-orcid":false,"given":"Caio Henrique","family":"Pelaio","sequence":"additional","affiliation":[{"name":"Instituto de Pesquisa Pel\u00e9 Pr\u00edncipe, Curitiba 80250-060, PR, Brazil"},{"name":"Biomedical and Clinical Analyses Department, Centro Universit\u00e1rio Curitiba, Curitiba 80220-181, PR, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe Baleche","family":"Cruz","sequence":"additional","affiliation":[{"name":"Instituto de Pesquisa Pel\u00e9 Pr\u00edncipe, Curitiba 80250-060, PR, Brazil"},{"name":"Medical School, Faculdade Evang\u00e9lica Mackenzie do Paran\u00e1, Curitiba 80730-000, PR, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanna Fischer","family":"Steil","sequence":"additional","affiliation":[{"name":"Faculdades Pequeno Pr\u00edncipe, Curitiba 80230-020, PR, Brazil"},{"name":"Instituto de Pesquisa Pel\u00e9 Pr\u00edncipe, Curitiba 80250-060, PR, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6638-6642","authenticated-orcid":false,"given":"Heloisa Ihle Garcia","family":"Giamberardino","sequence":"additional","affiliation":[{"name":"Hospital Pequeno Pr\u00edncipe, Curitiba 80250-060, PR, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina","family":"Prando","sequence":"additional","affiliation":[{"name":"Faculdades Pequeno Pr\u00edncipe, Curitiba 80230-020, PR, Brazil"},{"name":"Instituto de Pesquisa Pel\u00e9 Pr\u00edncipe, Curitiba 80250-060, PR, Brazil"},{"name":"Hospital Pequeno Pr\u00edncipe, Curitiba 80250-060, PR, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,6,27]]},"reference":[{"key":"ref_1","unstructured":"Brasil Minist\u00e9rio da Sa\u00fade (2023, May 06). 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