{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T04:03:57Z","timestamp":1792641837307,"version":"4.5.0"},"reference-count":32,"publisher":"MDPI AG","issue":"15","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Idiopathic scoliosis is common in adulthood and can impact patients\u2019 physical and psychological health. The Scoliosis Research Society-22 Questionnaire (SRS-22) has been designed to assess health-related quality of life (HRQOL) in idiopathic scoliosis, and it is the most used disease-specific outcome tool from adolescence to adulthood. More recently, the Italian Spine Youth Quality of Life (ISYQOL) international questionnaire was developed, which performs better than SRS-22 in adolescent spinal deformities. However, the ISYQOL questionnaire has never been tested in adults. This study compares the construct validity of ISYQOL and SRS-22 with the Rasch analysis (partial credit model). We recruited 150 adults and 50 adolescents with scoliosis (\u226530\u00b0 Cobb). SRS-22, but not ISQYOL, showed disordered categories and one item not fitting the Rasch model. A 21-item SRS-22 version with revised categories was arranged and further compared to ISYQOL. Both questionnaires showed multidimensionality, and some items (SRS-22 in a greater number) functioned differently in persons of different ages. However, the artefacts caused by multidimensionality and differential functioning had a low impact on the questionnaires\u2019 measures. The construct validity of ISYQOL International and the revised SRS-22 are comparable. Both questionnaires (but not the original SRS-22) can return measures of disease burden in adults with scoliosis.<\/jats:p>","DOI":"10.3390\/jcm12155071","type":"journal-article","created":{"date-parts":[[2023,8,2]],"date-time":"2023-08-02T11:17:17Z","timestamp":1690975037000},"page":"5071","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Measuring Quality of Life in Adults with Scoliosis: A Cross-Sectional Study Comparing SRS-22 and ISYQOL Questionnaires"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1256-5362","authenticated-orcid":false,"given":"Fabio","family":"Zaina","sequence":"first","affiliation":[{"name":"ISICO (Italian Scientific Spine Institute), Via Roberto Bellarmino 13\/1, 20141 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0943-9103","authenticated-orcid":false,"given":"Irene","family":"Ferrario","sequence":"additional","affiliation":[{"name":"ISICO (Italian Scientific Spine Institute), Via Roberto Bellarmino 13\/1, 20141 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3051-1031","authenticated-orcid":false,"given":"Antonio","family":"Caronni","sequence":"additional","affiliation":[{"name":"IRCCS, Istituto Auxologico Italiano, Department of Neurorehabilitation Sciences, Ospedale San Luca, 20149 Milan, Italy"},{"name":"Department of Biomedical Sciences for Health, Universit\u00e0 degli Studi di Milano, 20133 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9217-4117","authenticated-orcid":false,"given":"Stefano","family":"Scarano","sequence":"additional","affiliation":[{"name":"IRCCS, Istituto Auxologico Italiano, Department of Neurorehabilitation Sciences, Ospedale San Luca, 20149 Milan, Italy"},{"name":"Department of Biomedical Sciences for Health, Universit\u00e0 degli Studi di Milano, 20133 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6637-7797","authenticated-orcid":false,"given":"Sabrina","family":"Donzelli","sequence":"additional","affiliation":[{"name":"ISICO (Italian Scientific Spine Institute), Via Roberto Bellarmino 13\/1, 20141 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1878-2747","authenticated-orcid":false,"given":"Stefano","family":"Negrini","sequence":"additional","affiliation":[{"name":"Department of Biomedical, Surgical and Dental Sciences, University \u201cLa Statale\u201d, 20122 Milan, Italy"},{"name":"IRCCS Istituto Ortopedico Galeazzi, 20157 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,8,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s13013-017-0145-8","article-title":"2016 SOSORT Guidelines: Orthopaedic and Rehabilitation Treatment of Idiopathic Scoliosis during Growth","volume":"13","author":"Negrini","year":"2018","journal-title":"Scoliosis Spinal Disord."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.jspd.2017.12.014","article-title":"Clinically Significant Psychological and Emotional Distress in 32% of Adolescent Idiopathic Scoliosis Patients","volume":"6","author":"Sanders","year":"2018","journal-title":"Spine Deform."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"3027","DOI":"10.1097\/01.brs.0000249555.87601.fc","article-title":"A Review of Quality of Life and Psychosocial Issues in 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