{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:24:05Z","timestamp":1760149445953,"version":"build-2065373602"},"reference-count":29,"publisher":"MDPI AG","issue":"15","license":[{"start":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T00:00:00Z","timestamp":1691020800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Hilar bile duct strictures are mostly caused by malignant lesions. The morphological appearance of perihilar cholangiocarcinomas in various imaging modalities have other malignant and even benign mimics, which pose challenges to an accurate diagnosis and treatment and drive to futile surgery. Herein, we present the case of a 50-year-old woman admitted with jaundice and abdominal pain, elevated bilirubin level, liver function tests and carbohydrate antigen 19-9 level. Magnetic resonance cholangio-pancreatography (MR-CP) and the computed tomography with contrast enhancement revealed a suspected extrahepatic cholangiocarcinoma of the common bile duct. Further spontaneous resolution of the scenario, confirmed by diagnostic assessment, changed the clinical hypothesis in favor of a non-oncological disease. Indeed, the multidisciplinary evaluation supported a diagnosis of transient cholangitis secondary to non-evident intrahepatic lithiasis rather than cholangiocarcinoma. After a 26-month follow-up, the patient was asymptomatic with normal tumor markers and laboratory data. Consecutive MR-CPs showed no suspicion of malignancy. This case report underlines the need for an accurate preoperative assessment in patients with suspected cholangiocarcinoma.<\/jats:p>","DOI":"10.3390\/jcm12155104","type":"journal-article","created":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T11:23:03Z","timestamp":1691061783000},"page":"5104","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Bile Duct Lithiasis Mimicking a Perihilar Cholangiocarcinoma\u2014An Endless Dilemma: A Case Report"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2902-5143","authenticated-orcid":false,"given":"Marco","family":"Piccino","sequence":"first","affiliation":[{"name":"2nd Surgery Unit, \u201cCa\u2019 Foncello\u201d Regional Hospital, 31100 Treviso, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7086-2456","authenticated-orcid":false,"given":"Ilda","family":"Hoxhaj","sequence":"additional","affiliation":[{"name":"2nd Surgery Unit, \u201cCa\u2019 Foncello\u201d Regional Hospital, 31100 Treviso, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5372-2873","authenticated-orcid":false,"given":"Ugo","family":"Grossi","sequence":"additional","affiliation":[{"name":"2nd Surgery Unit, \u201cCa\u2019 Foncello\u201d Regional Hospital, 31100 Treviso, Italy"},{"name":"Surgical-Oncological-Gastroenterological Science Department (DISCOG), University of Padua, 35122 Padova, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3101-7588","authenticated-orcid":false,"given":"Maurizio","family":"Romano","sequence":"additional","affiliation":[{"name":"2nd Surgery Unit, \u201cCa\u2019 Foncello\u201d Regional Hospital, 31100 Treviso, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7055-7117","authenticated-orcid":false,"given":"Marco","family":"Brizzolari","sequence":"additional","affiliation":[{"name":"2nd Surgery Unit, \u201cCa\u2019 Foncello\u201d Regional Hospital, 31100 Treviso, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9965-1281","authenticated-orcid":false,"given":"Michele","family":"Scopelliti","sequence":"additional","affiliation":[{"name":"2nd Surgery Unit, \u201cCa\u2019 Foncello\u201d Regional Hospital, 31100 Treviso, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Finotti","sequence":"additional","affiliation":[{"name":"2nd Surgery Unit, \u201cCa\u2019 Foncello\u201d Regional Hospital, 31100 Treviso, Italy"},{"name":"Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX 75246, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5489-3009","authenticated-orcid":false,"given":"Giacomo","family":"Zanus","sequence":"additional","affiliation":[{"name":"2nd Surgery Unit, \u201cCa\u2019 Foncello\u201d Regional Hospital, 31100 Treviso, Italy"},{"name":"Surgical-Oncological-Gastroenterological Science Department (DISCOG), University of Padua, 35122 Padova, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,8,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1093\/gastro\/gou072","article-title":"Biliary strictures: Diagnostic considerations and approach","volume":"3","author":"Singh","year":"2015","journal-title":"Gastroenterol. 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