{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T03:58:43Z","timestamp":1782791923721,"version":"3.54.5"},"reference-count":34,"publisher":"MDPI AG","issue":"17","license":[{"start":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T00:00:00Z","timestamp":1692748800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>This article presents three cases of Descemet\u2019s membrane detachment (DMD) occurring during \u2018ab externo\u2019 phacocanaloplasty procedures in three patients with uncontrolled primary open-angle glaucoma (OAG) and discusses the management of this condition by reviewing the available literature. Following a successful 360\u00b0 cannulation of Schlemm\u2019s canal (SC), the microcatheter was withdrawn while an ophthalmic viscosurgical device (OVD) was injected into the canal. During passage through the inferonasal quadrant, a spontaneous separation of the posterior layer of the cornea was observed. Each case was managed differently after diagnosis, with the third case being drained intraoperatively based on experience gained from the previous cases. On the first postoperative day, slit-lamp biomicroscopy (BMC) revealed multiple DMDs in case one and a hyphema in the lower third of a deep anterior chamber. In the other two cases, a single DMD was observed. The second case developed hemorrhagic Descemet membrane detachment (HDMD), while the other two were non-hemorrhagic. In all three cases, anterior segment optical coherence tomography (AS-OCT) revealed the presence of retrocorneal hyperreflective membranes indicative of DMDs. These membranes were located in the periphery of the cornea and did not impact the visual axis. After evaluation, a small incision was made in the inferotemporal DMD of the first case. However, for the two remaining cases, a strategy of watchful waiting was deemed appropriate due to the location and size of the DMDs, as they did not affect the best-corrected visual acuity (BCVA). Over time, the patients demonstrated progressive improvement with a gradual reduction in the size of the DMDs.<\/jats:p>","DOI":"10.3390\/jcm12175461","type":"journal-article","created":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T08:01:21Z","timestamp":1692777681000},"page":"5461","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Descemet\u2019s Membrane Detachment during Phacocanaloplasty: Case Series and In-Depth Literature Review"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1094-0090","authenticated-orcid":false,"given":"Marta","family":"Orejudo de Rivas","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Lozano Blesa University Clinic Hospital, 50009 Zaragoza, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juana","family":"Mart\u00ednez Morales","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Lozano Blesa University Clinic Hospital, 50009 Zaragoza, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Pardina Claver","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Lozano Blesa University Clinic Hospital, 50009 Zaragoza, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"P\u00e9rez Garc\u00eda","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Lozano Blesa University Clinic Hospital, 50009 Zaragoza, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Itziar","family":"P\u00e9rez Navarro","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Lozano Blesa University Clinic Hospital, 50009 Zaragoza, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4804-2555","authenticated-orcid":false,"given":"Francisco J.","family":"Ascaso Puyuelo","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Lozano Blesa University Clinic Hospital, 50009 Zaragoza, Spain"},{"name":"Aragon Health Research Institute (IIS Aragon), 50018 Zaragoza, Spain"},{"name":"Department of Surgery, School of Medicine, University of Zaragoza, 50009 Zaragoza, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Aramburu Claver\u00eda","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Lozano Blesa University Clinic Hospital, 50009 Zaragoza, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Ib\u00e1\u00f1ez Alperte","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Lozano Blesa University Clinic Hospital, 50009 Zaragoza, Spain"},{"name":"Aragon Health Research Institute (IIS Aragon), 50018 Zaragoza, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,8,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1097\/ICO.0b013e318281af48","article-title":"Hemorrhagic Descemet Detachment After Combined Canaloplasty and Cataract Surgery","volume":"32","author":"Robert","year":"2013","journal-title":"Cornea"},{"key":"ref_2","first-page":"225","article-title":"Canaloplasty in the spotlight: Surgical alternatives and future perspectives","volume":"66","author":"Beres","year":"2022","journal-title":"Rom. 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