{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T11:01:43Z","timestamp":1786273303814,"version":"build-2736575974"},"reference-count":29,"publisher":"MDPI AG","issue":"17","license":[{"start":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T00:00:00Z","timestamp":1693180800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: The current design of biliopancreatic diversion with duodenal switch (BPD\/DS) and single anastomosis duodenal\u2013ileal bypass with sleeve (SADI-S) emphasizes the importance of the pylorus\u2019 preservation to reduce the incidence of marginal ulcer (MU) and dumping. However, no institutional studies have yet reported data on their prevalence. We aimed to assess the incidence of MU and dumping after duodenal switch (DS) and identify the associative factors. Methods: A multi-center review of patients who underwent BPD\/DS or SADI-S between 2008 and 2022. Baseline demographics, symptoms, and management of both complications were collected. Fisher\u2019s exact test was used for categorical variables and the independent t-test for continuous variables. Results: A total of 919 patients were included (74.6% female; age 42.5 years; BMI 54.6 kg\/m2) with mean follow-up of 31.5 months. Eight patients (0.9%) developed MU and seven (0.8%) had dumping. Patients who developed MU were more likely to be using non-steroidal anti-inflammatory drugs (NSAID) (p = 0.006) and have a longer operation time (p = 0.047). Primary versus revisional surgery, and BDP\/DS versus SADI-S were not associated with MU or dumping. Conclusions: The incidences of MU and dumping after DS were low. NSAID use and a longer operation time were associated with an increased risk of MU, whereas dumping was attributed to poor dietary habits.<\/jats:p>","DOI":"10.3390\/jcm12175600","type":"journal-article","created":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T06:10:22Z","timestamp":1693203022000},"page":"5600","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Marginal Ulcer and Dumping Syndrome in Patients after Duodenal Switch: A Multi-Centered Study"],"prefix":"10.3390","volume":"12","author":[{"given":"Marita","family":"Salame","sequence":"first","affiliation":[{"name":"Department of Surgery, Mayo Clinic, Rochester, MN 55905, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andre F.","family":"Teixeira","sequence":"additional","affiliation":[{"name":"Department of Surgery, Orlando Health, Orlando, FL 32806, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romulo","family":"Lind","sequence":"additional","affiliation":[{"name":"Department of Surgery, Orlando Health, Orlando, FL 32806, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilberto","family":"Ungson","sequence":"additional","affiliation":[{"name":"Department of Surgery, Cima Hospital, Hermosillo 83280, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Ghanem","sequence":"additional","affiliation":[{"name":"Department of Surgery, Orlando Health, Orlando, FL 32806, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9431-0728","authenticated-orcid":false,"given":"Kamal","family":"Abi Mosleh","sequence":"additional","affiliation":[{"name":"Department of Surgery, Mayo Clinic, Rochester, MN 55905, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad A.","family":"Jawad","sequence":"additional","affiliation":[{"name":"Department of Surgery, Orlando Health, Orlando, FL 32806, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barham K.","family":"Abu Dayyeh","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael L.","family":"Kendrick","sequence":"additional","affiliation":[{"name":"Department of Surgery, Mayo Clinic, Rochester, MN 55905, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar M.","family":"Ghanem","sequence":"additional","affiliation":[{"name":"Department of Surgery, Mayo Clinic, Rochester, MN 55905, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,8,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1016\/j.jamcollsurg.2008.08.022","article-title":"Association of Hypertension, Diabetes, Dyslipidemia, and Metabolic Syndrome with Obesity: Findings from the National Health and Nutrition Examination Survey, 1999 to 2004","volume":"207","author":"Nguyen","year":"2008","journal-title":"J. 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