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Birmingham","award":["HHSN268201800003I"],"award-info":[{"award-number":["HHSN268201800003I"]}]},{"name":"University of Alabama Birmingham","award":["HHSN268201800006I"],"award-info":[{"award-number":["HHSN268201800006I"]}]},{"name":"University of Alabama Birmingham","award":["HHSN268201800004I"],"award-info":[{"award-number":["HHSN268201800004I"]}]},{"name":"Northwestern University","award":["5T32HL007779-29"],"award-info":[{"award-number":["5T32HL007779-29"]}]},{"name":"Northwestern University","award":["R01HL098445"],"award-info":[{"award-number":["R01HL098445"]}]},{"name":"Northwestern University","award":["HHSN268201800005I"],"award-info":[{"award-number":["HHSN268201800005I"]}]},{"name":"Northwestern University","award":["HHSN268201800003I"],"award-info":[{"award-number":["HHSN268201800003I"]}]},{"name":"Northwestern University","award":["HHSN268201800006I"],"award-info":[{"award-number":["HHSN268201800006I"]}]},{"name":"Northwestern 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We examined the associations of physical activity, by intensity and type, and television viewing with prevalent NAFLD. Methods: Cross-sectional analysis of a population-based sample of 2726 Black (49%) and White (51%) adults (Mean (SD) age, 50 (3.6) years; 57.3% female) from the CARDIA study. Exposures were aerobic activity by intensity (moderate, vigorous; hours\/week); activity type (aerobic, muscle-strengthening; hours\/week); and television viewing (hours\/week), examined concurrently in all models and assessed by validated questionnaires. Our outcome was NAFLD (liver attenuation &lt; 51 Hounsfield Units), measured by non-contrast computed tomography, after exclusions for other causes of liver fat. Covariates were sex, age, race, study center, education, diet quality, smoking status, alcohol consumption, and body mass index or waist circumference. Results: 648 participants had NAFLD. In the fully adjusted modified Poisson regression model, the risk ratios per interquartile range of each exposure were moderate-intensity aerobic activity, 1.10 (95% CI, 0.97\u20131.26); vigorous-intensity aerobic activity, 0.72 (0.63\u20130.82); muscle-strengthening activity, 0.89 (0.80\u20131.01); and television viewing, 1.20 (1.10\u20131.32). Relative to less active participants with higher levels of television viewing, those who participated in \u22652 h\/week of both vigorous-intensity aerobic and muscle-strengthening activity and &lt;7 h\/week of television viewing had 65% lower risk of NAFLD (risk ratio = 0.35, 95% CI = 0.23\u20130.51). Conclusion: Adults who follow public health recommendations for vigorous-aerobic and muscle-strengthening activity, as well as minimize television viewing, are considerably less likely to have NAFLD than those who do not follow the recommendations and who have relatively high levels of television viewing.<\/jats:p>","DOI":"10.3390\/jcm12175603","type":"journal-article","created":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T06:10:22Z","timestamp":1693203022000},"page":"5603","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Aerobic and Muscle-Strengthening Physical Activity, Television Viewing, and Nonalcoholic Fatty Liver Disease: The CARDIA Study"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5313-7284","authenticated-orcid":false,"given":"Daniel J.","family":"McDonough","sequence":"first","affiliation":[{"name":"Division of Epidemiology & Community Health, University of Minnesota-Twin Cities, Minneapolis, MN 55455, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahesh","family":"Mathew","sequence":"additional","affiliation":[{"name":"Division of Epidemiology & Community Health, University of Minnesota-Twin Cities, Minneapolis, MN 55455, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zachary C.","family":"Pope","sequence":"additional","affiliation":[{"name":"Well Living Lab, Rochester, NY 55902, USA"},{"name":"Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, NY 14625, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9920-6257","authenticated-orcid":false,"given":"Pamela J.","family":"Schreiner","sequence":"additional","affiliation":[{"name":"Division of Epidemiology & Community Health, University of Minnesota-Twin Cities, Minneapolis, MN 55455, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7232-0543","authenticated-orcid":false,"suffix":"Jr.","given":"David R.","family":"Jacobs","sequence":"additional","affiliation":[{"name":"Division of Epidemiology & Community Health, University of Minnesota-Twin Cities, Minneapolis, MN 55455, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6264-2573","authenticated-orcid":false,"given":"Lisa B.","family":"VanWagner","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John Jeffrey","family":"Carr","sequence":"additional","affiliation":[{"name":"Vanderbilt University Medical Center, Vanderbilt University, Nashville, TN 37232, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6659-3441","authenticated-orcid":false,"given":"James G.","family":"Terry","sequence":"additional","affiliation":[{"name":"Vanderbilt University Medical Center, Vanderbilt University, Nashville, TN 37232, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelley Pettee","family":"Gabriel","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jared P.","family":"Reis","sequence":"additional","affiliation":[{"name":"National Heart Lung and Blood Institute, Bethesda, MD 20892, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark A.","family":"Pereira","sequence":"additional","affiliation":[{"name":"Division of Epidemiology & Community Health, University of Minnesota-Twin Cities, Minneapolis, MN 55455, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,8,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1056\/NEJMra1503519","article-title":"Cause, pathogenesis, and treatment of nonalcoholic steatohepatitis","volume":"377","author":"Diehl","year":"2017","journal-title":"N. 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