{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T06:21:30Z","timestamp":1771482090475,"version":"3.50.1"},"reference-count":61,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2023,9,20]],"date-time":"2023-09-20T00:00:00Z","timestamp":1695168000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003196","name":"Italian Ministry of Health","doi-asserted-by":"publisher","award":["Ricerca Corrente programme 2022 2024"],"award-info":[{"award-number":["Ricerca Corrente programme 2022 2024"]}],"id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>In this case report, real-time neuropsychological testing (RTNT) and music listening were applied for resections in the left temporal\u2013parietal lobe during awake surgery (AS). The case is based on a 66-year-old with glioblastoma and alterations in expressive language and memory deficit. Neuropsychological assessment was run at baseline (2\u20133 days before surgery), discharge from hospital (2\u20133 days after surgery), and follow-up (1 month and 3 months). RTNT was started before beginning the anesthetic approach (T0) and during tumor excision (T1 and T2). At T0, T1, and T2 (before performing neuropsychological tests), music listening was applied. Before AS and after music listening, the patient reported a decrease in depression and anxiety. During AS, an improvement was shown in all cognitive parameters collected at T0, T1, and T2. After the excision and music listening, the patient reported a further decrease in depression and anxiety. Three days post surgery, and at follow-ups of one month and three months, the patient reported a further improvement in cognitive aspects, the absence of depression, and a reduction in anxiety symptoms. In conclusion, RTNT has been useful in detecting cognitive function levels during tumor excision. Music listening during AS decreased the patient\u2019s anxiety and depression symptoms.<\/jats:p>","DOI":"10.3390\/jcm12186086","type":"journal-article","created":{"date-parts":[[2023,9,20]],"date-time":"2023-09-20T22:38:45Z","timestamp":1695249525000},"page":"6086","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Real-Time Neuropsychological Testing (RTNT) and Music Listening during Glioblastoma Excision in Awake Surgery: A Case Report"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5905-6063","authenticated-orcid":false,"given":"Grazia","family":"D\u2019Onofrio","sequence":"first","affiliation":[{"name":"Clinical Psychology Service, Health Department, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, 71013 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadia","family":"Icolaro","sequence":"additional","affiliation":[{"name":"Complex Unit of Neurosurgery, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, 71013 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Fazzari","sequence":"additional","affiliation":[{"name":"Complex Unit of Neurosurgery, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, 71013 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domenico","family":"Catapano","sequence":"additional","affiliation":[{"name":"Complex Unit of Neurosurgery, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, 71013 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1783-9710","authenticated-orcid":false,"given":"Antonello","family":"Curcio","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, BIOMORF Department, University of Messina, 98122 Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Izzi","sequence":"additional","affiliation":[{"name":"Complex Unit of Anesthesia-2, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, 71013 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aldo","family":"Manuali","sequence":"additional","affiliation":[{"name":"Complex Unit of Anesthesia-2, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, 71013 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuliano","family":"Bisceglia","sequence":"additional","affiliation":[{"name":"Complex Unit of Anesthesia-2, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, 71013 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelo","family":"Tancredi","sequence":"additional","affiliation":[{"name":"Complex Unit of Anesthesia-2, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, 71013 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Marchello","sequence":"additional","affiliation":[{"name":"Complex Unit of Anesthesia-2, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, 71013 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreaserena","family":"Recchia","sequence":"additional","affiliation":[{"name":"Complex Unit of Anesthesia-2, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, 71013 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1734-2213","authenticated-orcid":false,"given":"Maria Pia","family":"Tonti","sequence":"additional","affiliation":[{"name":"Complex Unit of Anesthesia-2, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, 71013 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Pazienza","sequence":"additional","affiliation":[{"name":"Complex Unit of Radiology, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, 71013 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Carotenuto","sequence":"additional","affiliation":[{"name":"Complex Unit of Neurosurgery, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, 71013 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Costanzo De","family":"Bonis","sequence":"additional","affiliation":[{"name":"Complex Unit of Neurosurgery, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, 71013 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luciano","family":"Savarese","sequence":"additional","affiliation":[{"name":"Complex Unit of Neurosurgery, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, 71013 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfredo Del","family":"Gaudio","sequence":"additional","affiliation":[{"name":"Complex Unit of Anesthesia-2, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, 71013 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9535-0908","authenticated-orcid":false,"given":"Leonardo Pio","family":"Gorgoglione","sequence":"additional","affiliation":[{"name":"Complex Unit of Neurosurgery, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, 71013 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,9,20]]},"reference":[{"key":"ref_1","unstructured":"WHO Classification of Tumours Editorial Board (2021). World Health Organization Classification of Tumours of the Central Nervous System, International Agency for Research on Cancer. [5th ed.]."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"2309","DOI":"10.1016\/j.ejca.2014.05.019","article-title":"Changing Incidence and Improved Survival of Gliomas","volume":"50","author":"Ho","year":"2014","journal-title":"Eur. J. Cancer"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1159\/000521201","article-title":"Simultaneous Presentation of Glioblastoma Multiforme in Divorced Spouses","volume":"15","author":"Fehr","year":"2022","journal-title":"Case Rep. Oncol."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"De Vleeschouwer, S. (2017). Glioblastoma, Codon Publications.","DOI":"10.15586\/codon.glioblastoma.2017"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"e000348","DOI":"10.1136\/jitc-2019-000348","article-title":"Biomarkers for Immunotherapy for Treatment of Glioblastoma","volume":"8","author":"Lynes","year":"2020","journal-title":"J. Immunother. Cancer"},{"key":"ref_6","unstructured":"(2023, May 03). CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2013\u20132017\u2014PubMed, Available online: https:\/\/pubmed.ncbi.nlm.nih.gov\/33123732\/."},{"key":"ref_7","unstructured":"Sharma, S., Hashmi, M.F., and Kumar, A. (2023). Intracranial Hypertension, StatPearls Publishing."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"e172","DOI":"10.1016\/j.wneu.2018.05.232","article-title":"Group Changes in Cognitive Performance After Surgery Mask Changes in Individual Patients with Glioblastoma","volume":"117","author":"Rijnen","year":"2018","journal-title":"World Neurosurg."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/j.jgo.2019.06.015","article-title":"Neurocognitive Evaluation in Older Adult Patients Affected by Glioma","volume":"11","author":"Tanzilli","year":"2020","journal-title":"J. Geriatr. Oncol."},{"key":"ref_10","unstructured":"(2023, May 03). Early Measures of Cognitive Function Predict Survival in Patients with Newly Diagnosed Glioblastoma\u2014PubMed, Available online: https:\/\/pubmed.ncbi.nlm.nih.gov\/22508762\/."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1796","DOI":"10.1212\/01.WNL.0000098892.33018.4C","article-title":"The Prognostic Value of Cognitive Functioning in the Survival of Patients with High-Grade Glioma","volume":"61","author":"Klein","year":"2003","journal-title":"Neurology"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/s11060-018-03081-z","article-title":"Depressive Symptoms and Executive Function in Relation to Survival in Patients with Glioblastoma","volume":"142","author":"Noll","year":"2019","journal-title":"J. Neurooncol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"106089","DOI":"10.1016\/j.clineuro.2020.106089","article-title":"Cognitive and Linguistic Outcomes after Awake Craniotomy in Patients with High-Grade Gliomas","volume":"198","author":"Bonifazi","year":"2020","journal-title":"Clin. Neurol. Neurosurg."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"760569","DOI":"10.3389\/fnhum.2021.760569","article-title":"Real-Time Neuropsychological Testing Protocol for Left Temporal Brain Tumor Surgery: A Technical Note and Case Report","volume":"15","author":"Tomasino","year":"2021","journal-title":"Front. Hum. Neurosci."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1177\/0194599819856604","article-title":"Music therapy for pain and anxiety management in nasal bone fracture reduction: Randomized controlled clinical trial","volume":"161","author":"Ortega","year":"2019","journal-title":"Otolaryngol. Head Neck Surg."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1159\/000365085","article-title":"Effect of music on labor pain relief, anxiety level and postpartum analgesic requirement: A randomized controlled clinical trial","volume":"78","author":"Simavli","year":"2014","journal-title":"Gynecol. Obstet. Investig."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.urology.2011.09.037","article-title":"The effect of noise-cancelling headphones or music on pain perception and anxiety in men undergoing transrectal prostate biopsy","volume":"79","author":"Tsivian","year":"2012","journal-title":"Urology"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/j.jacr.2015.12.004","article-title":"Imaging-guided core-needle breast biopsy: Impact of meditation and music interventions on patient anxiety, pain, and fatigue","volume":"13","author":"Soo","year":"2016","journal-title":"J. Am. Coll. Radiol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1089\/end.2016.0005","article-title":"Reduced pain and anxiety with music and noise-canceling headphones during shockwave lithotripsy","volume":"30","author":"Karalar","year":"2016","journal-title":"J. Endourol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.jcma.2016.08.010","article-title":"Effect of music on level of anxiety in patients undergoing colonoscopy without sedaion","volume":"80","author":"Ko","year":"2017","journal-title":"J. Chin. Med. Assoc."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1153.e1","DOI":"10.1016\/j.joms.2019.02.028","article-title":"The effects of music listening during extraction of the impacted mandibular third molar on the autonomic nervous system and psychological state","volume":"77","author":"Yamashita","year":"2019","journal-title":"J. Oral Maxillofac. Surg."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.ctim.2019.04.005","article-title":"The effects of music on anxiety and pain in patients during carotid endarterectomy under regional anesthesia: A randomized controlled trial","volume":"44","author":"Kavakli","year":"2019","journal-title":"Complement. Ther. Med."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1213\/ANE.0000000000005696","article-title":"Effect of a Musical Intervention During the Implantation of a Central Venous Catheter or a Dialysis Catheter in the Intensive Care Unit: A Prospective Randomized Pilot Study","volume":"134","author":"Jacquier","year":"2022","journal-title":"Anesth. Analg."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1016\/S0140-6736(15)60169-6","article-title":"Music as an aid for postoperative recovery in adults: A systematic review and meta-analysis","volume":"386","author":"Hole","year":"2015","journal-title":"Lancet"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.ctim.2017.03.007","article-title":"Effects of music listening on anxiety and physiological responses in patients undergoing awake craniotomy","volume":"32","author":"Wu","year":"2017","journal-title":"Complement. Ther. Med."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1017\/cjn.2014.127","article-title":"Music is Beneficial for Awake Craniotomy Patients: A Qualitative Study","volume":"42","author":"Venkatraghavan","year":"2015","journal-title":"Can. J. Neurol. Sci."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1136\/bmj.39335.541782.AD","article-title":"STROBE Initiative Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for Reporting Observational Studies","volume":"335","author":"Altman","year":"2007","journal-title":"BMJ"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"Mini-mental state: A practical method for grading the cognitive state of patients for the clinician","volume":"12","author":"Folstein","year":"1975","journal-title":"J. Psychiatr. Res."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/0278-2626(92)90112-Y","article-title":"Quantitative and qualitative analyses of clock drawings in Alzheimer\u2019s and Huntington\u2019s disease","volume":"18","author":"Rouleau","year":"1992","journal-title":"Brain Cogn."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1212\/WNL.55.11.1621","article-title":"The FAB: A frontal assessment battery at bedside","volume":"55","author":"Dubois","year":"2000","journal-title":"Neurology"},{"key":"ref_31","unstructured":"Babcock, H., and Levy, L. (1940). The Measurement of Efficiency of Mental Functioning (Revised Examination): Test and Manual of Directions, C.H. Stoelting."},{"key":"ref_32","unstructured":"Wechsler, D. (1991). Wechsler Intelligence Scale for Children\u2014III, The Psychological Corporation."},{"key":"ref_33","first-page":"21","article-title":"Standardizzazione e taratura italiana di test neuropsicologici","volume":"8","author":"Spinnler","year":"1987","journal-title":"Ital. J. Neurol. Sci."},{"key":"ref_34","unstructured":"Lezak, M., Howieson, D., Bigler, E., and Tranel, D. (2012). Neuropsychological Assessment, Oxford University Press."},{"key":"ref_35","unstructured":"Kaplan, E., Goodglass, H., and Weintraub, S. (1983). The Boston Naming Test, Lea & Febiger."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"271","DOI":"10.2466\/pms.1958.8.3.271","article-title":"Validity of the Trail Making test as an indicator of organic brain damage","volume":"8","author":"Reitan","year":"1958","journal-title":"Percept. Mot. Ski."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1007\/s10072-015-2203-4","article-title":"STIMA: A short screening test for ideo-motor apraxia, selective for action meaning and bodily district","volume":"36","author":"Tessari","year":"2015","journal-title":"Neurol. Sci."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/S0010-9452(66)80028-X","article-title":"Oral Apraxia and Aphasia","volume":"2","author":"Pieczuro","year":"1966","journal-title":"Cortex"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/S0010-9452(64)80020-4","article-title":"Constructional apraxia and hemispheric locus of lesion","volume":"1","author":"Arrigoni","year":"1964","journal-title":"Cortex"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"2308","DOI":"10.1212\/WNL.44.12.2308","article-title":"The Neuropsychiatric Inventory: Comprehensive assessment of psychopathology in dementia","volume":"44","author":"Cummings","year":"1994","journal-title":"Neurology"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"35","DOI":"10.2147\/LRA.S135413","article-title":"Local anesthetics for brain tumor resection: Current perspectives","volume":"11","author":"Potters","year":"2018","journal-title":"Local Reg. Anesth."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.wneu.2017.05.053","article-title":"Awake craniotomy anesthesia: A comparison between the monitored anesthesia care versus the asleep-awake-asleep technique","volume":"104","author":"Eseonu","year":"2017","journal-title":"World Neurosurg."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"316","DOI":"10.3171\/jns.1989.71.3.0316","article-title":"Cortical language localization in left, dominant hemisphere. An electrical stimulation mapping investigation in 117 patients","volume":"71","author":"Ojemann","year":"1989","journal-title":"J. Neurosurg."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1056\/NEJMoa067819","article-title":"Functional outcome after language mapping for glioma resection","volume":"358","author":"Sanai","year":"2008","journal-title":"N. Engl. J. Med."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1227\/01.neu.0000243290.36910.a2","article-title":"Intraoperative language localization in multilingual patients with gliomas","volume":"59","author":"Bello","year":"2006","journal-title":"Neurosurgery"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1055\/s-2003-39334","article-title":"Neuronavigation combined with electrophysiological monitoring for surgery of lesions in eloquent brain areas in 42cases: A retrospective comparison of the neurological outcome and the quality of resection with a control group withsimilar lesions","volume":"46","author":"Reithmeier","year":"2003","journal-title":"Min-Minim. Invasive Neurosurg."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1227\/01.NEU.0000298902.69473.77","article-title":"Resection of World Health Organization grade II gliomas involving Broca\u2019s area: Methodological and functional considerations","volume":"61","author":"Benzagmout","year":"2007","journal-title":"Neurosurgery"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s00701-005-0706-0","article-title":"Multimodal protocol for awake craniotomy in language cortex tumour surgery","volume":"148","author":"Picht","year":"2006","journal-title":"Acta Neurochir."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"877","DOI":"10.3171\/2015.10.JNS15740","article-title":"Brain mapping: A novel intraoperative neuropsychological approach","volume":"125","author":"Skrap","year":"2016","journal-title":"J. Neurosurg."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.clineuro.2016.05.022","article-title":"The sensory-motor profile awake-A new tool for pre-, intra-, and post operative assessment of sensory-motor function","volume":"147","author":"Becker","year":"2016","journal-title":"Clin. Neurol. Neurosurg."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/S1474-4422(05)70140-X","article-title":"Lessons from brain mapping in surgery for low-grade glioma: Insights into associations between tumour and brain plasticity","volume":"4","author":"Duffau","year":"2005","journal-title":"Lancet Neurol."},{"key":"ref_52","first-page":"1199","article-title":"High-definition fiber tractography for the evaluation of perilesional white matter tracts in high-grade glioma surgery","volume":"17","author":"Abhinav","year":"2015","journal-title":"Neuro-Oncology"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"2348","DOI":"10.1093\/brain\/awq175","article-title":"The structural plasticity of white matter networks following anterior temporal lobe resection","volume":"133","author":"Yogarajah","year":"2010","journal-title":"Brain J. Neurol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"106816","DOI":"10.1016\/j.clineuro.2021.106816","article-title":"Neurocognitive deficits in patients suffering from glioma in speech-relevant areas of the left hemisphere","volume":"207","author":"Behrens","year":"2021","journal-title":"Clin. Neurol. Neurosurg."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1007\/s00415-020-10303-w","article-title":"Cognitive impairments are independently associated with shorter survival in diffuse glioma patients","volume":"268","author":"Ruis","year":"2021","journal-title":"J. Neurol."},{"key":"ref_56","first-page":"3761398","article-title":"The Effect of Perioperative Music Listening on Patient Satisfaction, Anxiety, and Depression: A Quasiexperimental Study","volume":"2020","author":"Tan","year":"2020","journal-title":"Anesthesiol. Res. Pract."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"433","DOI":"10.3233\/JAD-190361","article-title":"Preferred Music Listening Intervention in Nursing Home Residents with Cognitive Impairment: A Randomized Intervention Study","volume":"70","author":"Cunha","year":"2019","journal-title":"J. Alzheimer\u2019s Dis."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1136\/rapm-2018-100251","article-title":"Music versus midazolam during preoperative nerve block placements: A prospective randomized controlled study","volume":"44","author":"Graff","year":"2019","journal-title":"Reg. Anesth. Pain Med."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1080\/13554790902729473","article-title":"Speaking without Broca\u2019s area after tumor resection","volume":"15","author":"Plaza","year":"2009","journal-title":"Neurocase"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.neures.2009.07.002","article-title":"Does post-lesional subcortical plasticity exist in the human brain?","volume":"65","author":"Duffau","year":"2009","journal-title":"Neurosci. Res."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.neucir.2020.07.004","article-title":"Intraoperative Brain Mapping during Awake Surgery in Symptomatic Supratentorial Cavernomas","volume":"32","year":"2021","journal-title":"Neurocirug\u00eda Engl. Ed."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/12\/18\/6086\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T20:54:08Z","timestamp":1760129648000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/12\/18\/6086"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,20]]},"references-count":61,"journal-issue":{"issue":"18","published-online":{"date-parts":[[2023,9]]}},"alternative-id":["jcm12186086"],"URL":"https:\/\/doi.org\/10.3390\/jcm12186086","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,20]]}}}