{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:47:47Z","timestamp":1787500067524,"version":"build-2736575974"},"reference-count":82,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T00:00:00Z","timestamp":1696464000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Fluid overload, a prevalent complication in patients with renal disease and hypertension, significantly impacts patient morbidity and mortality. The daily clinical challenges that clinicians face include how to identify fluid overload early enough in the course of the disease to prevent adverse outcomes and to guide and potentially reduce the intensity of the diuresis. Traditional methods for evaluating fluid status, such as pitting edema, pulmonary crackles, or chest radiography primarily assess extracellular fluid and do not accurately reflect intravascular volume status or venous congestion. This review explores the rationale, mechanism, and evidence behind more recent methods used to assess volume status, namely, lung ultrasound, inferior vena cava (IVC) ultrasound, venous excess ultrasound score, and basic and advanced cardiac echocardiographic techniques. These methods offer a more accurate and objective assessment of fluid status, providing real-time, non-invasive measures of intravascular volume and venous congestion. The methods we discuss are primarily used in inpatient settings, but, given the increased pervasiveness of ultrasound technology, some could soon expand to the outpatient setting.<\/jats:p>","DOI":"10.3390\/jcm12196368","type":"journal-article","created":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T09:14:22Z","timestamp":1696497262000},"page":"6368","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Objective Methods of Assessing Fluid Status to Optimize Volume Management in Kidney Disease and Hypertension: The Importance of Ultrasound"],"prefix":"10.3390","volume":"12","author":[{"given":"Sharad","family":"Patel","sequence":"first","affiliation":[{"name":"Division of Critical Care Medicine, Cooper University Health Care, Camden, NJ 08103, USA"},{"name":"Department of Medicine, Cooper Medical School of Rowan University, Camden, NJ 08103, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Green","sequence":"additional","affiliation":[{"name":"Division of Critical Care Medicine, Cooper University Health Care, Camden, NJ 08103, USA"},{"name":"Department of Medicine, Cooper Medical School of Rowan University, Camden, NJ 08103, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandhya","family":"Ashokumar","sequence":"additional","affiliation":[{"name":"Division of Critical Care Medicine, Cooper University Health Care, Camden, NJ 08103, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Hoke","sequence":"additional","affiliation":[{"name":"Department of Medicine, Cooper University Health Care, Camden, NJ 08103, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Sebastien","family":"Rachoin","sequence":"additional","affiliation":[{"name":"Division of Critical Care Medicine, Cooper University Health Care, Camden, NJ 08103, USA"},{"name":"Department of Medicine, Cooper Medical School of Rowan University, Camden, NJ 08103, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,10,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2182","DOI":"10.1093\/ndt\/gfaa182","article-title":"Volume overload in hemodialysis: Diagnosis, cardiovascular consequences, and management","volume":"36","author":"Loutradis","year":"2021","journal-title":"Nephrol. Dial. Transpl."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1053\/j.ajkd.2021.09.029","article-title":"Diuretics in States of Volume Overload: Core Curriculum 2022","volume":"80","author":"Novak","year":"2022","journal-title":"Am. J. Kidney Dis."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1097\/CCM.0000000000004617","article-title":"Fluid Overload and Mortality in Adult Critical Care Patients-A Systematic Review and Meta-Analysis of Observational Studies","volume":"48","author":"Messmer","year":"2020","journal-title":"Crit. Care Med."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1046\/j.1523-1755.2003.00064.x","article-title":"Nonadherence in hemodialysis: Associations with mortality, hospitalization, and practice patterns in the DOPPS","volume":"64","author":"Saran","year":"2003","journal-title":"Kidney Int."},{"key":"ref_5","first-page":"S12","article-title":"Congestion is an important diagnostic and therapeutic target in heart failure","volume":"7","author":"Gheorghiade","year":"2006","journal-title":"Rev. Cardiovasc. Med."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1002\/ehf2.13118","article-title":"Congestive nephropathy: A neglected entity? Proposal for diagnostic criteria and future perspectives","volume":"8","author":"Grone","year":"2021","journal-title":"ESC Heart Fail"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1159\/000526902","article-title":"Diagnosis of Fluid Overload: From Conventional to Contemporary Concepts","volume":"12","author":"Koratala","year":"2022","journal-title":"Cardiorenal Med."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"2080","DOI":"10.1378\/chest.122.6.2080","article-title":"Prognostic value of extravascular lung water in critically ill patients","volume":"122","author":"Sakka","year":"2002","journal-title":"Chest"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/S0034-7094(12)70146-0","article-title":"Postoperative delirium in intensive care patients: Risk factors and outcome","volume":"62","author":"Veiga","year":"2012","journal-title":"Rev. Bras. Anestesiol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.ijcard.2013.09.014","article-title":"Pathophysiology of cardiorenal syndrome in decompensated heart failure: Role of lung-right heart-kidney interaction","volume":"169","author":"Guazzi","year":"2013","journal-title":"Int. J. Cardiol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"361","DOI":"10.5603\/AIT.2014.0060","article-title":"Fluid overload, de-resuscitation, and outcomes in critically ill or injured patients: A systematic review with suggestions for clinical practice","volume":"46","author":"Malbrain","year":"2014","journal-title":"Anaesthesiol. Intensive Ther."},{"key":"ref_12","first-page":"1","article-title":"The costs of fluid overload in the adult intensive care unit: Is a small-volume infusion model a proactive solution?","volume":"7","author":"Child","year":"2015","journal-title":"Clin. Outcomes Res."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1513\/AnnalsATS.201504-187OC","article-title":"Volume Overload: Prevalence, Risk Factors, and Functional Outcome in Survivors of Septic Shock","volume":"12","author":"Mitchell","year":"2015","journal-title":"Ann. Am. Thorac. Soc."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"39","DOI":"10.2215\/CJN.03610414","article-title":"Association of fluid overload with cardiovascular morbidity and all-cause mortality in stages 4 and 5 CKD","volume":"10","author":"Tsai","year":"2015","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1053\/j.ajkd.2013.06.011","article-title":"Association of fluid overload with kidney disease progression in advanced CKD: A prospective cohort study","volume":"63","author":"Tsai","year":"2014","journal-title":"Am. J. Kidney Dis."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"e753","DOI":"10.1097\/CCM.0000000000003862","article-title":"Fluid Overload Associates With Major Adverse Kidney Events in Critically Ill Patients With Acute Kidney Injury Requiring Continuous Renal Replacement Therapy","volume":"47","author":"Woodward","year":"2019","journal-title":"Crit. Care Med."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1097\/01.sla.0000094387.50865.23","article-title":"Effects of intravenous fluid restriction on postoperative complications: Comparison of two perioperative fluid regimens: A randomized assessor-blinded multicenter trial","volume":"238","author":"Brandstrup","year":"2003","journal-title":"Ann. Surg."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/j.ejvs.2007.03.010","article-title":"Positive fluid balance is associated with complications after elective open infrarenal abdominal aortic aneurysm repair","volume":"34","author":"McArdle","year":"2007","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"44","DOI":"10.5500\/wjt.v8.i2.44","article-title":"Cumulative positive fluid balance is a risk factor for acute kidney injury and requirement for renal replacement therapy after liver transplantation","volume":"8","author":"Codes","year":"2018","journal-title":"World J. Transpl."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1016\/j.amjcard.2018.07.023","article-title":"Relation of Volume Overload to Clinical Outcomes in Acute Heart Failure (From ASCEND-HF)","volume":"122","author":"Fudim","year":"2018","journal-title":"Am. J. Cardiol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1067\/mhj.2000.110933","article-title":"Freedom from congestion predicts good survival despite previous class IV symptoms of heart failure","volume":"140","author":"Lucas","year":"2000","journal-title":"Am. Heart J."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1944","DOI":"10.1001\/jama.294.15.1944","article-title":"Does this dyspneic patient in the emergency department have congestive heart failure?","volume":"294","author":"Wang","year":"2005","journal-title":"JAMA"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1001\/jama.1997.03540450068038","article-title":"Can the clinical examination diagnose left-sided heart failure in adults?","volume":"277","author":"Badgett","year":"1997","journal-title":"JAMA"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.2215\/CJN.03890416","article-title":"The Agreement between Auscultation and Lung Ultrasound in Hemodialysis Patients: The LUST Study","volume":"11","author":"Torino","year":"2016","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"47","DOI":"10.7326\/0003-4819-119-1-199307010-00009","article-title":"The teaching and practice of cardiac auscultation during internal medicine and cardiology training. A nationwide survey","volume":"119","author":"Mangione","year":"1993","journal-title":"Ann. Intern. Med."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1007\/BF02599919","article-title":"Accuracy and reliability of apical S3 gallop detection","volume":"10","author":"Westman","year":"1995","journal-title":"J. Gen. Intern. Med."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"2357","DOI":"10.1016\/j.jacc.2007.09.021","article-title":"Natriuretic peptides","volume":"50","author":"Daniels","year":"2007","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.clinbiochem.2014.01.032","article-title":"Cardiac biomarkers in heart failure","volume":"47","author":"Liquori","year":"2014","journal-title":"Clin. Biochem."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1056\/NEJMoa020233","article-title":"Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failure","volume":"347","author":"Maisel","year":"2002","journal-title":"N. Engl. J. Med."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/S0735-1097(01)01744-2","article-title":"Utility of a rapid B-natriuretic peptide assay in differentiating congestive heart failure from lung disease in patients presenting with dyspnea","volume":"39","author":"Morrison","year":"2002","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1016\/j.amjcard.2004.12.032","article-title":"The N-terminal Pro-BNP investigation of dyspnea in the emergency department (PRIDE) study","volume":"95","author":"Januzzi","year":"2005","journal-title":"Am. J. Cardiol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1454986","DOI":"10.1155\/2017\/1454986","article-title":"Natriuretic Peptides as Biomarkers for Congestive States: The Cardiorenal Divergence","volume":"2017","author":"Koratala","year":"2017","journal-title":"Dis. Markers"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1016\/j.jchf.2015.07.014","article-title":"Amino-Terminal Pro-B-Type Natriuretic Peptide for Diagnosis and Prognosis in Patients With Renal Dysfunction: A Systematic Review and Meta-Analysis","volume":"3","author":"Schaub","year":"2015","journal-title":"JACC Heart Fail"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.jacc.2005.09.025","article-title":"Amino-terminal pro-B-type natriuretic peptide and B-type natriuretic peptide in the general community: Determinants and detection of left ventricular dysfunction","volume":"47","author":"Boerrigter","year":"2006","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/j.ahj.2005.10.011","article-title":"How obesity affects the cut-points for B-type natriuretic peptide in the diagnosis of acute heart failure. Results from the Breathing Not Properly Multinational Study","volume":"151","author":"Daniels","year":"2006","journal-title":"Am. Heart J."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1093\/eurheartj\/ehab911","article-title":"Heart failure with preserved ejection fraction in patients with normal natriuretic peptide levels is associated with increased morbidity and mortality","volume":"43","author":"Verbrugge","year":"2022","journal-title":"Eur. Heart J."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"1952","DOI":"10.1093\/eurheartj\/ehac121","article-title":"BNP: Biomarker Not Perfect in heart failure with preserved ejection fraction","volume":"43","author":"Shah","year":"2022","journal-title":"Eur. Heart J."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.annemergmed.2005.04.003","article-title":"Adhere Scientific Advisory Committee I, Study G: Prevalence of negative chest radiography results in the emergency department patient with decompensated heart failure","volume":"47","author":"Collins","year":"2006","journal-title":"Ann. Emerg. Med."},{"key":"ref_39","first-page":"1663","article-title":"Fuhlbrigge AMKC: Diagnostic procedures in Respiratory disease","volume":"Volume 1","author":"Braunmald","year":"2015","journal-title":"Harrison\u2019s Principles of Internal Medicine"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1007\/s00134-012-2513-4","article-title":"International evidence-based recommendations for point-of-care lung ultrasound","volume":"38","author":"Volpicelli","year":"2012","journal-title":"Intensive Care Med."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1164\/rccm.201802-0227LE","article-title":"Training for Lung Ultrasound Score Measurement in Critically Ill Patients","volume":"198","author":"Rouby","year":"2018","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1378\/chest.07-2800","article-title":"Relevance of lung ultrasound in the diagnosis of acute respiratory failure: The BLUE protocol","volume":"134","author":"Lichtenstein","year":"2008","journal-title":"Chest"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1164\/ajrccm.156.5.96-07096","article-title":"The comet-tail artifact. An ultrasound sign of alveolar-interstitial syndrome","volume":"156","author":"Lichtenstein","year":"1997","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1378\/chest.127.5.1690","article-title":"\u201cUltrasound comet-tail images\u201d: A marker of pulmonary edema: A comparative study with wedge pressure and extravascular lung water","volume":"127","author":"Agricola","year":"2005","journal-title":"Chest"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1378\/chest.09-0001","article-title":"A-lines and B-lines: Lung ultrasound as a bedside tool for predicting pulmonary artery occlusion pressure in the critically ill","volume":"136","author":"Lichtenstein","year":"2009","journal-title":"Chest"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1378\/chest.08-1811","article-title":"Ultrasound assessment for extravascular lung water in patients undergoing hemodialysis. Time course for resolution","volume":"135","author":"Noble","year":"2009","journal-title":"Chest"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1097\/ALN.0000000000000300","article-title":"Lung ultrasound predicts well extravascular lung water but is of limited usefulness in the prediction of wedge pressure","volume":"121","author":"Volpicelli","year":"2014","journal-title":"Anesthesiology"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/s13054-015-0756-5","article-title":"Simplified lung ultrasound protocol shows excellent prediction of extravascular lung water in ventilated intensive care patients","volume":"19","author":"Enghard","year":"2015","journal-title":"Crit. Care"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1378\/chest.14-2608","article-title":"Lung Ultrasound-Implemented Diagnosis of Acute Decompensated Heart Failure in the ED: A SIMEU Multicenter Study","volume":"148","author":"Pivetta","year":"2015","journal-title":"Chest"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/S2213-2600(14)70135-3","article-title":"Point-of-care ultrasonography in patients admitted with respiratory symptoms: A single-blind, randomised controlled trial","volume":"2","author":"Laursen","year":"2014","journal-title":"Lancet Respir. Med."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/j.echo.2007.01.005","article-title":"Reappraisal of the use of inferior vena cava for estimating right atrial pressure","volume":"20","author":"Brennan","year":"2007","journal-title":"J. Am. Soc. Echocardiogr."},{"key":"ref_52","first-page":"233","article-title":"Recommendations for cardiac chamber quantification by echocardiography in adults: An update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging","volume":"16","author":"Lang","year":"2015","journal-title":"J. Am. Soc. Echocardiogr."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0002-9149(87)80084-X","article-title":"Effects of positional changes on inferior vena caval size and dynamics and correlations with right-sided cardiac pressure","volume":"59","author":"Nakao","year":"1987","journal-title":"Am. J. Cardiol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.echo.2010.05.010","article-title":"Guidelines for the echocardiographic assessment of the right heart in adults: A report from the American Society of Echocardiography endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology, and the Canadian Society of Echocardiography","volume":"23","author":"Rudski","year":"2010","journal-title":"J. Am. Soc. Echocardiogr."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"154108","DOI":"10.1016\/j.jcrc.2022.154108","article-title":"Agreement between subcostal and transhepatic longitudinal imaging of the inferior vena cava for the evaluation of fluid responsiveness: A systematic review","volume":"71","author":"Astuto","year":"2022","journal-title":"J. Crit. Care"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/s40635-023-00505-7","article-title":"Assessment of the inferior vena cava collapsibility from subcostal and trans-hepatic imaging using both M-mode or artificial intelligence: A prospective study on healthy volunteers","volume":"11","author":"Sanfilippo","year":"2023","journal-title":"Intensive Care Med. Exp."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/s40635-023-00529-z","article-title":"Inferior vena cava distensibility from subcostal and trans-hepatic imaging using both M-mode or artificial intelligence: A prospective study on mechanically ventilated patients","volume":"11","author":"Sanfilippo","year":"2023","journal-title":"Intensive Care Med. Exp."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1111\/j.1553-2712.2009.00627.x","article-title":"Inferior vena cava percentage collapse during respiration is affected by the sampling location: An ultrasound study in healthy volunteers","volume":"17","author":"Wallace","year":"2010","journal-title":"Acad. Emerg. Med."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1007\/s00134-004-2233-5","article-title":"The respiratory variation in inferior vena cava diameter as a guide to fluid therapy","volume":"30","author":"Feissel","year":"2004","journal-title":"Intensive Care Med."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1007\/s00134-004-2259-8","article-title":"Respiratory changes in inferior vena cava diameter are helpful in predicting fluid responsiveness in ventilated septic patients","volume":"30","author":"Barbier","year":"2004","journal-title":"Intensive Care Med."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/j.ajem.2015.02.006","article-title":"The utility of inferior vena cava diameter and the degree of inspiratory collapse in patients with systolic heart failure","volume":"33","author":"Besli","year":"2015","journal-title":"Am. J. Emerg. Med."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.jcmg.2012.08.012","article-title":"IVC diameter in patients with chronic heart failure: Relationships and prognostic significance","volume":"6","author":"Pellicori","year":"2013","journal-title":"JACC Cardiovasc. Imaging"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1016\/j.amjcard.2017.02.007","article-title":"Usefulness of Serial Measurements of Inferior Vena Cava Diameter by Vscan(TM) to Identify Patients With Heart Failure at High Risk of Hospitalization","volume":"119","author":"Khandwalla","year":"2017","journal-title":"Am. J. Cardiol."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1002\/jhm.2620","article-title":"Admission inferior vena cava measurements are associated with mortality after hospitalization for acute decompensated heart failure","volume":"11","author":"Soni","year":"2016","journal-title":"J. Hosp. Med."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/0735-1097(88)91531-8","article-title":"Sonospirometry: A new method for noninvasive estimation of mean right atrial pressure based on two-dimensional echographic measurements of the inferior vena cava during measured inspiration","volume":"11","author":"Simonson","year":"1988","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1016\/S0894-7317(99)70153-7","article-title":"Dilated inferior vena cava: A common echocardiographic finding in highly trained elite athletes","volume":"12","author":"Goldhammer","year":"1999","journal-title":"J. Am. Soc. Echocardiogr."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s13089-020-00163-w","article-title":"Quantifying systemic congestion with Point-Of-Care ultrasound: Development of the venous excess ultrasound grading system","volume":"12","author":"Rola","year":"2020","journal-title":"Ultrasound J."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1186\/s13054-023-04471-0","article-title":"Correlation between the VExUS score and right atrial pressure: A pilot prospective observational study","volume":"27","author":"Longino","year":"2023","journal-title":"Crit. Care"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1186\/s13054-020-03330-6","article-title":"The use of venous Doppler to predict adverse kidney events in a general ICU cohort","volume":"24","author":"Spiegel","year":"2020","journal-title":"Crit. Care"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1186\/s13054-023-04524-4","article-title":"Prevalence of systemic venous congestion assessed by Venous Excess Ultrasound Grading System (VExUS) and association with acute kidney injury in a general ICU cohort: A prospective multicentric study","volume":"27","author":"Andrei","year":"2023","journal-title":"Crit. Care"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1159\/000511714","article-title":"Dynamic Changes in Portal Vein Flow during Decongestion in Patients with Heart Failure and Cardio-Renal Syndrome: A POCUS Case Series","volume":"11","author":"Argaiz","year":"2021","journal-title":"Cardiorenal Med."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/s13089-021-00232-8","article-title":"Clinical applications of the venous excess ultrasound (VExUS) score: Conceptual review and case series","volume":"13","author":"Rola","year":"2021","journal-title":"Ultrasound J."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1097\/MEJ.0000000000000866","article-title":"Assessing left ventricular systolic function by emergency physician using point of care echocardiography compared to expert: Systematic review and meta-analysis","volume":"29","author":"Albaroudi","year":"2022","journal-title":"Eur. J. Emerg. Med."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.echo.2018.06.004","article-title":"Guidelines for Performing a Comprehensive Transthoracic Echocardiographic Examination in Adults: Recommendations from the American Society of Echocardiography","volume":"32","author":"Mitchell","year":"2019","journal-title":"J. Am. Soc. Echocardiogr."},{"key":"ref_75","doi-asserted-by":"crossref","unstructured":"Kim, J.S., Yang, J.W., Yoo, J.S., Choi, S.O., and Han, B.G. (2017). Association between E\/e ratio and fluid overload in patients with predialysis chronic kidney disease. PLoS ONE, 12.","DOI":"10.1371\/journal.pone.0184764"},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1016\/S0735-1097(97)00344-6","article-title":"Doppler tissue imaging: A noninvasive technique for evaluation of left ventricular relaxation and estimation of filling pressures","volume":"30","author":"Nagueh","year":"1997","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.echo.2016.01.011","article-title":"Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging","volume":"29","author":"Nagueh","year":"2016","journal-title":"J. Am. Soc. Echocardiogr."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1186\/s13054-016-1421-3","article-title":"Application of a simplified definition of diastolic function in severe sepsis and septic shock","volume":"20","author":"Lanspa","year":"2016","journal-title":"Crit. Care"},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1111\/echo.15462","article-title":"Full and simplified assessment of left ventricular diastolic function in covid-19 patients admitted to ICU: Feasibility, incidence, and association with mortality","volume":"39","author":"Dezio","year":"2022","journal-title":"Echocardiography"},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1007\/s12630-018-1068-4","article-title":"Transthoracic echocardiographic evaluation of the heart and great vessels","volume":"65","author":"Denault","year":"2018","journal-title":"Can. J. Anaesth."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"e1111","DOI":"10.1016\/j.jcrc.2013.08.008","article-title":"Bedside assessment of right atrial pressure in critically ill septic patients using tissue Doppler ultrasonography","volume":"28","author":"Arbo","year":"2013","journal-title":"J. Crit. Care"},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.ijcard.2016.09.034","article-title":"Echo and natriuretic peptide guided therapy improves outcome and reduces worsening renal function in systolic heart failure: An observational study of 1137 outpatients","volume":"224","author":"Simioniuc","year":"2016","journal-title":"Int. J. Cardiol."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/12\/19\/6368\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T21:01:32Z","timestamp":1760130092000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/12\/19\/6368"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,5]]},"references-count":82,"journal-issue":{"issue":"19","published-online":{"date-parts":[[2023,10]]}},"alternative-id":["jcm12196368"],"URL":"https:\/\/doi.org\/10.3390\/jcm12196368","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,5]]}}}