{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T19:53:41Z","timestamp":1787428421216,"version":"build-2736575974"},"reference-count":18,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T00:00:00Z","timestamp":1696550400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Purpose: This study evaluated the agreement and reproducibility of ACA measurements obtained using the built-in software of the CASIA2 (Version 3G.1) and the measurements derived from expert clinicians. Methods: Healthy volunteers underwent ophthalmological evaluation and AS-OCT examination. ACA measurements derived from automated and manual SS location were obtained using the CASIA2 automated software and clinician identification, respectively. The intraobserver, interobserver reproducibility, CASIA2\u2013human grader reproducibility and CASIA2 repeatability were assessed using intraclass correlation coefficients (ICCs). Results: The study examined 58 eyes of 30 participants. The CASIA2 software showed excellent repeatability for all ACA parameters (ICC &gt; 0.84). Intraobserver, interobserver, and CASIA2\u2013human grader reproducibility were also excellent (ICC &gt; 0.87). Interobserver agreement was high, except for nasal TISA500, differing between observers 1 and 2 (p &lt; 0.05). The agreement between CASIA2 measurements and human graders was high, except for nasal TISA500, where observer 1 values were smaller (p &lt; 0.05). Conclusion: The CASIA2 built-in software reliably measures ACA parameters in healthy individuals, demonstrating high consistency. Although a small difference was observed in nasal TISA500 measurements, interobserver and CASIA2\u2013human grader reproducibility remained excellent. Automated SS detection has the potential to facilitate evaluation and monitoring of primary angle closure disease.<\/jats:p>","DOI":"10.3390\/jcm12196381","type":"journal-article","created":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T07:49:29Z","timestamp":1696578569000},"page":"6381","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Agreement and Reproducibility of Anterior Chamber Angle Measurements between CASIA2 Built-In Software and Human Graders"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2519-2355","authenticated-orcid":false,"given":"Gustavo","family":"Espinoza","sequence":"first","affiliation":[{"name":"Centro Oftalmol\u00f3gico Virgilio Galvis, Floridablanca 681004, Santander, Colombia"},{"name":"Fundaci\u00f3n Oftalmol\u00f3gica de Santander, Floridablanca 681004, Santander, Colombia"},{"name":"Facultad de Ciencias de la Salud, Universidad Aut\u00f3noma de Bucaramanga, Bucaramanga 680002, Santander, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katheriene","family":"Iglesias","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n Oftalmol\u00f3gica de Santander, Floridablanca 681004, Santander, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan C.","family":"Parra","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n Oftalmol\u00f3gica de Santander, Floridablanca 681004, Santander, Colombia"},{"name":"Facultad de Ciencias de la Salud, Universidad Aut\u00f3noma de Bucaramanga, Bucaramanga 680002, Santander, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9557-6691","authenticated-orcid":false,"given":"Ignacio","family":"Rodriguez-Una","sequence":"additional","affiliation":[{"name":"Instituto Universitario Fern\u00e1ndez-Vega, Fundaci\u00f3n de Investigaci\u00f3n Oftalmol\u00f3gica, Universidad de Oviedo, 33012 Oviedo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Serrano-Gomez","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias de la Salud, Universidad Aut\u00f3noma de Bucaramanga, Bucaramanga 680002, Santander, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelica M.","family":"Prada","sequence":"additional","affiliation":[{"name":"Centro Oftalmol\u00f3gico Virgilio Galvis, Floridablanca 681004, Santander, Colombia"},{"name":"Fundaci\u00f3n Oftalmol\u00f3gica de Santander, Floridablanca 681004, Santander, Colombia"},{"name":"Facultad de Ciencias de la Salud, Universidad Aut\u00f3noma de Bucaramanga, Bucaramanga 680002, Santander, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virgilio","family":"Galvis","sequence":"additional","affiliation":[{"name":"Centro Oftalmol\u00f3gico Virgilio Galvis, Floridablanca 681004, Santander, Colombia"},{"name":"Fundaci\u00f3n Oftalmol\u00f3gica de Santander, Floridablanca 681004, Santander, Colombia"},{"name":"Facultad de Ciencias de la Salud, Universidad Aut\u00f3noma de Bucaramanga, Bucaramanga 680002, Santander, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,10,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1016\/j.ophtha.2014.05.013","article-title":"Global prevalence of glaucoma and projections of glaucoma burden through 2040: A systematic review and meta-analysis","volume":"121","author":"Tham","year":"2014","journal-title":"Ophthalmology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1097\/01.ijg.0000212287.62798.8f","article-title":"Use of gonioscopy in Medicare beneficiaries before glaucoma surgery","volume":"15","author":"Coleman","year":"2006","journal-title":"J. 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