{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T04:53:52Z","timestamp":1780548832590,"version":"3.54.1"},"reference-count":70,"publisher":"MDPI AG","issue":"20","license":[{"start":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T00:00:00Z","timestamp":1697155200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Cocaine addiction is a significant problem worldwide. The development of addiction involves a reward system, which consists of certain brain regions like the ventral tegmental area, nucleus accumbens, and prefrontal cortex. Currently, there are no approved medications for treating cocaine dependence, so researchers are actively searching for effective treatments that can impact the brain. One potential treatment under investigation is transcranial direct current stimulation (tDCS), a non-invasive method of stimulating the brain to modulate its activity. In this review, we explore the use of tDCS in treating cocaine addiction. We found nine relevant articles via a literature search, and the results indicate that applying tDCS to the right dorsolateral prefrontal cortex (DLPFC) holds promise for reducing drug cravings in individuals with cocaine addiction. The review also discusses the possible mechanisms by which tDCS works and provides recommendations for future research in this field.<\/jats:p>","DOI":"10.3390\/jcm12206511","type":"journal-article","created":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T10:04:39Z","timestamp":1697191479000},"page":"6511","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The Effect of Transcranial Direct Current Stimulation (tDCS) on Cocaine Addiction: A Narrative Review"],"prefix":"10.3390","volume":"12","author":[{"given":"James","family":"Chmiel","sequence":"first","affiliation":[{"name":"Institute of Neurofeedback and tDCS Poland, 70-393 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0777-4565","authenticated-orcid":false,"given":"Justyna","family":"Chojdak-\u0141ukasiewicz","sequence":"additional","affiliation":[{"name":"Department and Clinic of Neurology, Wroc\u0142aw Medical University, 54-235 Wroc\u0142aw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerzy","family":"Leszek","sequence":"additional","affiliation":[{"name":"Department and Clinic of Psychiatry, Wroc\u0142aw Medical University, 54-235 Wroc\u0142aw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,10,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2358","DOI":"10.1021\/acschemneuro.8b00117","article-title":"DARK classics in chemical neuroscience: Cocaine","volume":"9","author":"Drake","year":"2018","journal-title":"ACS Chem. 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