{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T12:38:45Z","timestamp":1791895125543,"version":"4.3.4"},"reference-count":29,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T00:00:00Z","timestamp":1700179200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>QOL questionnaires assess patients\u2019 perception on surgical outcomes. We reviewed 1354 patients with spinal deformity. Four hundred and twenty-eight patients had &gt;10 years of follow-up. The SRS-22r questionnaire was completed before surgery, at 6\/12\/24 months, 5\u201310 years and &gt;10 years postoperatively. Patients with &gt;10 years of follow-up completed the EQ-5D VAS\/index and the VAS for back\/leg pain. We used QOL data reporting in the general population of 20\u201329 and 30\u201339 years of age to compare against our patient cohort. Among the patients, 993 had AIS, 80 congenital scoliosis, 102 syndromic or secondary scoliosis, 105 Scheuermann kyphosis and 40 low-grade and 34 high-grade spondylolisthesis. SRS-22r total and domain scores improved from preoperative to follow-up in all diagnosis categories. At &gt;10 years after surgery, patients with congenital scoliosis and Scheuermann kyphosis had better SRS-22r total\/domain and EQ-5D (index\/VAS) scores along with lower VAS back\/leg pain scores compared to the other groups. Patients with congenital scoliosis and Scheuermann kyphosis had comparable SRS-22r total\/domain, EQ-5D (index\/VAS) and VAS back\/leg pain scores to the general population in the 20\u201329 year category and better scores than the 30\u201339 year group. Patients with AIS, syndromic\/secondary scoliosis and low\/high-grade spondylolisthesis had reduced SRS-22r total\/domain and EQ-5D (index\/VAS) scores and higher VAS back\/leg pain scores compared to the 20\u201329 year group but comparable scores to the 30\u201339 year group. Patients with spinal deformity reported improved QOL and high satisfaction after surgery which was maintained at &gt;10 years of follow-up. Patients with congenital scoliosis and Scheuermann kyphosis had better QOL outcomes (comparable to the general population of similar age) as opposed to other types of scoliosis or lumbosacral spondylolisthesis.<\/jats:p>","DOI":"10.3390\/jcm12227142","type":"journal-article","created":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T09:23:43Z","timestamp":1700213023000},"page":"7142","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Long-Term Health-Related Quality of Life (QOL) after Paediatric Spinal Deformity Surgery and Comparison with the General Population"],"prefix":"10.3390","volume":"12","author":[{"given":"Athanasios I.","family":"Tsirikos","sequence":"first","affiliation":[{"name":"Scottish National Spine Deformity Centre, Royal Hospital for Children and Young People, Edinburgh EH16 4TJ, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Garc\u00eda-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Scottish National Spine Deformity Centre, Royal Hospital for Children and Young People, Edinburgh EH16 4TJ, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,11,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1016\/S0140-6736(08)60658-3","article-title":"Adolescent idiopathic scoliosis","volume":"371","author":"Weinstein","year":"2008","journal-title":"Lancet"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1097\/00007632-200404150-00008","article-title":"The influence of spine and trunk defoirity on preoperative idiopathic scoliosis patients\u2019 health-related quality of life questionnaire responses","volume":"29","author":"Asher","year":"2004","journal-title":"Spine"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1097\/01.brs.0000155425.04536.f7","article-title":"Correlation of radiographic parameters and clinical symptoms in adult scoliosis","volume":"30","author":"Glassman","year":"2005","journal-title":"Spine"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1046\/j.1524-4733.1999.02210.x","article-title":"Recommendations for evaluating the validity of quality of life claims for labeling and promotion","volume":"2","author":"Leidi","year":"1999","journal-title":"Value Health"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1097\/BRS.0000000000004545","article-title":"Health-related quality of life of patients with adolescent idiopathic scoliosis at least 40 years after surgery","volume":"48","author":"Akazawa","year":"2023","journal-title":"Spine"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"E373","DOI":"10.1097\/01.BRS.0000084267.41183.75","article-title":"Back pain and function 23 years after fusion for adolescent idiopathic scoliosis: A case-control study-part II","volume":"28","author":"Danielsson","year":"2003","journal-title":"Spine"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/s13013-015-0045-8","article-title":"Health-related quality-of-life in adolescent idiopathic scoliosis patients 25 years after treatment","volume":"10","author":"Simony","year":"2015","journal-title":"Scoliosis"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"E922","DOI":"10.1097\/BRS.0000000000000991","article-title":"Minimum 20 years long-term clinical outcome after spinal fusion and instrumentation for scoliosis: Comparison of the SRS-22 patient questionnaire with that in nonscoliosis group","volume":"40","author":"Iida","year":"2015","journal-title":"Spine"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1007\/s43390-020-00217-y","article-title":"Very long-term clinical and radiographic outcomes after posterior spinal fusion with pedicular screws for thoracic adolescent idiopathic scoliosis","volume":"9","author":"Darnis","year":"2021","journal-title":"Spine Deform."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1007\/s00586-006-0147-3","article-title":"Minimum 10 years follow-up surgical results of adolescent idiopathic scoliosis patients treated with TSRH instrumentation","volume":"16","author":"Benli","year":"2007","journal-title":"Eur. 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