{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T23:54:08Z","timestamp":1777593248290,"version":"3.51.4"},"reference-count":26,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T00:00:00Z","timestamp":1700179200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Purpose: Acquired defects of the central face pose significant challenges in achieving acceptable cosmetic and functional outcomes. The site, size, and depth of tissue loss often render local tissues inadequate for the repair of major nasal defects. In this article, we aim to demonstrate the efficacy of radial forearm-free flaps as an ideal choice for various central facial unit reconstructions. Methods: This study encompassed patients treated between 2020 and 2022 who underwent facial reconstruction using radial forearm flaps. These flaps were employed in eleven patients with defects involving the lower lid, nose, upper lip, and lower lip. Additionally, we used osteocutaneous flaps in one patient to reconstruct a right nasal bone defect. In three patients requiring medial and lateral canthal tendon reconstruction in one case and oral sphincter reconstruction in two cases, the palmaris longus tendon was included with the flap. Results: In the majority of cases, we achieved good to excellent aesthetic and functional results. Notably, there were no instances of flap failure or partial necrosis in this series. All patients experienced uneventful healing at the donor site. Conclusions: The radial forearm-free flap stands as an ideal and reliable method for reconstructing various facial defects. It offers efficient and thin-conforming skin coverage.<\/jats:p>","DOI":"10.3390\/jcm12227148","type":"journal-article","created":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T09:23:43Z","timestamp":1700213023000},"page":"7148","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The Central Facial Defect Reconstruction Using a Radial Forearm Free Flap after Malignant Cutaneous Tumor Ablation"],"prefix":"10.3390","volume":"12","author":[{"given":"Kyusang","family":"Cho","sequence":"first","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam 13620, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinsol","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam 13620, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4372-6955","authenticated-orcid":false,"given":"Seokchan","family":"Eun","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam 13620, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,11,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1097\/01.PRS.0000164683.34767.2F","article-title":"Microsurgical reconstruction of the nasal lining","volume":"115","author":"Walton","year":"2005","journal-title":"Plast. Reconstr. Surg."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/S0007-1226(56)80036-2","article-title":"Restoration of the Face Covering by Means of","volume":"9","year":"1956","journal-title":"Br. J. Plast. Surg."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"101","DOI":"10.4236\/mps.2020.104012","article-title":"The Use of Rotation Flap to Cover a Facial Defect-A case Study","volume":"10","author":"Nsaful","year":"2020","journal-title":"Mod. Plast. Surg."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Orabona, G.D., Maffia, F., Audino, G., Abbate, V., Germano, C., Bonavolonta, P., Romano, A., Villari, R., Mormile, M., and Califano, L. (2022). The Use of Matriderm\u00ae for Scalp Full-Thickness Defects Reconstruction: A Case series. J. Clin. Med., 11.","DOI":"10.3390\/jcm11206041"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1002\/1098-2752(2000)20:4<195::AID-MICR10>3.0.CO;2-W","article-title":"Radial forearm free tissue transfer for head and neck reconstruction: Versatility and reliability of a single donor site","volume":"20","author":"Santamaria","year":"2000","journal-title":"Microsurgery"},{"key":"ref_6","first-page":"ic18","article-title":"Reconstruction of a nasal defect with a radial forearm flap following trauma of a paramedian forehead flap","volume":"17","author":"Pulikkottil","year":"2017","journal-title":"Eplasty"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1002\/micr.22200","article-title":"Intraoral anastomosis of a prelaminated radial forearm flap in reconstruction of a large persistent cleft palate","volume":"34","author":"Landes","year":"2014","journal-title":"Microsurgery"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"854e","DOI":"10.1097\/PRS.0b013e31824a9e7f","article-title":"Reconstruction of total nasal defect including skin, bone, and lining, using a single free radial forearm osteocutaneous perforator flap","volume":"129","author":"Fujioka","year":"2012","journal-title":"Plast. Reconstr. Surg."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"3636","DOI":"10.3390\/jcm12113636","article-title":"The Folded Radial Forearm Flap in Lip and Nose Reconstruction-Still a Unique Choice","volume":"12","author":"Tobias","year":"2023","journal-title":"J. Clin. Med."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1177\/0194599815571536","article-title":"Reconstruction of the naso-orbitalethmoid(NOE) complex using the osteocutaneous radial forearm flap(OCRFF)","volume":"152","author":"Cannady","year":"2015","journal-title":"Otolaryngol. Head Neck Surg."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.bjps.2008.06.053","article-title":"The radial forearm free flap: A review of microsurgical options","volume":"62","author":"Chardon","year":"2009","journal-title":"J. Plast. Reconstr. Aesthetic Surg."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1097\/PRS.0b013e3181fed686","article-title":"Microvascular repair of heminasal, subtotal, and total nasal defects with a folded radial forearm flap and a full-thickness forehead flap","volume":"127","author":"Menick","year":"2011","journal-title":"Plast. Reconstr. Surg."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1097\/00000637-200109000-00005","article-title":"Creating two independent fasciocutaneous free flaps from a single radial forearm donor site","volume":"47","author":"Mustafa","year":"2001","journal-title":"Ann. Plast. Surg."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1054\/bjps.1999.3294","article-title":"A rare variant of the radial artery: Clinical considerations in raising a radial forearm flap","volume":"53","author":"Sasaki","year":"2000","journal-title":"Br. J. Plast. Surg."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"828e","DOI":"10.1097\/PRS.0000000000010089","article-title":"Preoperative examination is not associated with postoperative function following radial forearm free flap harvest","volume":"151","author":"Emanuelli","year":"2023","journal-title":"Plast. Reconstr. Surg."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"2473974X211006927","DOI":"10.1177\/2473974X211006927","article-title":"Outcomes of single anastomoses for superficial and deep-system venous drainage of radial forearm free flaps","volume":"5","author":"Moreno","year":"2021","journal-title":"OTO Open"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1097\/00006534-199810000-00030","article-title":"Reliability of the venae comitantes in venous drainage of the free radial forearm flaps","volume":"102","author":"Demirkan","year":"1998","journal-title":"Plast. Reconstr. Surg."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"bcr2014207147","DOI":"10.1136\/bcr-2014-207147","article-title":"Osteocutaneous radial forearm free flap in subtotal nasal reconstruction","volume":"2014","author":"Moore","year":"2014","journal-title":"BMJ Case Rep."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"306","DOI":"10.4103\/ijps.IJPS_81_18","article-title":"Extended adipofascial wrap around radial forearm flap for hard palate reconstruction","volume":"51","author":"Ashok","year":"2018","journal-title":"Indian J. Plast. Surg."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1080\/23320885.2018.1549494","article-title":"A unique method for total nasal defect reconstruction\u2014Prefabricated innervated osteocutaneous radial forearm free flap","volume":"6","author":"Ahcan","year":"2019","journal-title":"Plast. Surg. Hand Surg."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.bjps.2006.03.058","article-title":"Eyelid reconstruction with a composite radial forearm palmaris longus tendon flap","volume":"60","author":"Ueda","year":"2007","journal-title":"J. Plast. Reconstr. Aesthetic Surg."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1002\/micr.30410","article-title":"Functional reconstruction of total upper eyelid defects with a composite radial forearm-palmaris longus tenocutaneous free flap: A report of two cases","volume":"39","author":"Iwanaga","year":"2019","journal-title":"Microsurgery"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1097\/SAP.0b013e31818b4515","article-title":"Free radial forearm flap lip reconstruction: A Clinical series and case reports of technical refinements","volume":"62","author":"Daya","year":"2009","journal-title":"Ann. Plast. Surg."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"e75","DOI":"10.1016\/j.bjps.2009.01.034","article-title":"Simultaneous total upper and lower lip reconstruction with a free radial forearm-palmaris longus tendon and brachioradialis chimeric flap","volume":"63","author":"Daya","year":"2010","journal-title":"J. Plast. Reconstr. Aesthetic Surg."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Lin, N.C., Lin, S.L., and Tsai, K.Y. (2020). Barrel-shaped design of the forearm free flap for lower lip reconstruction: A pilot case-control study. BMC Surg., 20.","DOI":"10.1186\/s12893-020-00792-x"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1080\/2000656X.2021.1883631","article-title":"The use of ipsilateral skin grafts or local flaps for the closure of a free radial forearm flap donor site: A systematic review","volume":"55","author":"Shimbo","year":"2021","journal-title":"J. Plast. Surg. Hand Surg."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/12\/22\/7148\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T21:24:42Z","timestamp":1760131482000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/12\/22\/7148"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,17]]},"references-count":26,"journal-issue":{"issue":"22","published-online":{"date-parts":[[2023,11]]}},"alternative-id":["jcm12227148"],"URL":"https:\/\/doi.org\/10.3390\/jcm12227148","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,17]]}}}