{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T07:16:27Z","timestamp":1760426187434,"version":"build-2065373602"},"reference-count":32,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2023,12,17]],"date-time":"2023-12-17T00:00:00Z","timestamp":1702771200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Few data are available about results after procedures of resection and megaprosthesis at the hip in very elderly patients. The aim of our study was to ascertain survival and complications in patients aged 80 or older undergoing these major orthopedic procedures. A consecutive series of 27 procedures in 26 patients aged 80\u201393 years was evaluated. In total, 15 procedures were performed due to oncological diseases, 6 were performed following joint arthroplasty failures or periprosthetic fractures, and 6 were performed after trauma or trauma sequelae. Survival of the patients ranged from 0 to 122 months. Overall survival was 56% at 3 years, 24% at 5 years, and 16% at 8 years. An early postoperative death during the first 3 months occurred in five patients (18.5%). The only preoperative parameter negatively affecting survival was preoperative hemoglobin lower than 11 g\/dL. Local complications were similar to reported rates in all-age patients\u2019 series. In our experience, resection and megaprosthetic reconstruction can also be a valid choice in very elderly patients, with 56% of patients living more than two years from surgery and 24% more than five. Nevertheless, early postoperative deaths are frequent. A multidisciplinary evaluation of frailty of the patient must be accomplished, and patients and relatives must be informed about the risks of the procedure.<\/jats:p>","DOI":"10.3390\/jcm12247740","type":"journal-article","created":{"date-parts":[[2023,12,18]],"date-time":"2023-12-18T10:04:47Z","timestamp":1702893887000},"page":"7740","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Survival and Results after Resection and Reconstruction with Megaprosthesis at the Hip in Octogenarians"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0637-6896","authenticated-orcid":false,"given":"Guido","family":"Scoccianti","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Oncology, Careggi University Hospital, 50134 Firenze, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matteo","family":"Innocenti","sequence":"additional","affiliation":[{"name":"Orthopaedic Clinic, Careggi University Hospital, 50134 Firenze, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4271-8278","authenticated-orcid":false,"given":"Roberto","family":"Scanferla","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Oncology, Careggi University Hospital, 50134 Firenze, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5490-672X","authenticated-orcid":false,"given":"Federico","family":"Scolari","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, University of Florence, 50121 Florence, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Muratori","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Oncology, Careggi University Hospital, 50134 Firenze, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Ungar","sequence":"additional","affiliation":[{"name":"Department of Internal and Geriatric Medicine, Careggi University Hospital, 50134 Firenze, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7764-8919","authenticated-orcid":false,"given":"Carlo","family":"Rostagno","sequence":"additional","affiliation":[{"name":"Department of Internal and Postoperative Medicine, Careggi University Hospital, 50134 Firenze, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3912-3943","authenticated-orcid":false,"given":"Domenico Andrea","family":"Campanacci","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Oncology, Careggi University Hospital, 50134 Firenze, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,12,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1302\/0301-620X.99B3.BJJ-2016-0822.R1","article-title":"Proximal femoral replacement in contemporary revision total hip arthroplasty for severe femoral bone loss: A review of outcomes","volume":"99","author":"Viste","year":"2017","journal-title":"Bone Jt. 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