{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T15:49:43Z","timestamp":1789141783507,"version":"build-2803163510"},"reference-count":54,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T00:00:00Z","timestamp":1704931200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Colegio de Fisioterapeutas de Galicia"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>(1) Background: Manual lymphatic drainage (MLD), included within the complex decongestive therapy, as a therapy for the treatment of lymphedema has raised controversy about its benefits for lymphedema after breast cancer. The aim of this research is to test the effects of MLD on lymphedema after breast cancer during the treatment maintenance phase. (2) Methods: A randomized, single-blinded, controlled crossover trial was conducted to analyze the effects of a manual lymphatic drainage intervention compared to a control group without MLD intervention for the treatment of lymphedema. Arm volume measured by circumference measurement, subcutaneous tissue thickness measured by ultrasound, and the sensation of pain, heaviness, and swelling were evaluated as outcome measures. (3) Results: For the control group, an increase in volume was found in some of the circumference and subcutaneous tissue thickness measurements, in addition to a worsening of arm pain, swelling and heaviness. (4) Conclusion: The absence of treatment based on MLD in lymphedema after breast cancer worsens volume measurements, as well as arm heaviness. Therefore, it would be advisable to carry out this type of therapy as part of the maintenance treatment for lymphedema in breast cancer.<\/jats:p>","DOI":"10.3390\/jcm13020402","type":"journal-article","created":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T03:21:41Z","timestamp":1704943301000},"page":"402","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Is the Absence of Manual Lymphatic Drainage-Based Treatment in Lymphedema after Breast Cancer Harmful? A Randomized Crossover Study"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9507-789X","authenticated-orcid":false,"given":"Iria","family":"Da Cu\u00f1a-Carrera","sequence":"first","affiliation":[{"name":"Clinic Physiotherapy Group, Galicia South Health Research Institute, Servicio Galego de Sa\u00fade, 36312 Vigo, Spain"},{"name":"Faculty of Physiotherapy, Campus A Xunqueira s\/n, University of Vigo, 36005 Pontevedra, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6541-988X","authenticated-orcid":false,"given":"Mercedes","family":"Soto-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Clinic Physiotherapy Group, Galicia South Health Research Institute, Servicio Galego de Sa\u00fade, 36312 Vigo, Spain"},{"name":"Faculty of Physiotherapy, Campus A Xunqueira s\/n, University of Vigo, 36005 Pontevedra, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roc\u00edo","family":"Abalo-N\u00fa\u00f1ez","sequence":"additional","affiliation":[{"name":"Clinic Physiotherapy Group, Galicia South Health Research Institute, Servicio Galego de Sa\u00fade, 36312 Vigo, Spain"},{"name":"Faculty of Physiotherapy, Campus A Xunqueira s\/n, University of Vigo, 36005 Pontevedra, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5625-7628","authenticated-orcid":false,"given":"Eva M.","family":"Lantar\u00f3n-Caeiro","sequence":"additional","affiliation":[{"name":"Clinic Physiotherapy Group, Galicia South Health Research Institute, Servicio Galego de Sa\u00fade, 36312 Vigo, Spain"},{"name":"Faculty of Physiotherapy, Campus A Xunqueira s\/n, University of Vigo, 36005 Pontevedra, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,1,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1245\/s10434-009-0452-2","article-title":"The risk of developing arm lymphedema among breast cancer survivors: A meta-analysis of treatment factors","volume":"16","author":"Tsai","year":"2009","journal-title":"Ann. 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