{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T18:27:55Z","timestamp":1794335275352,"version":"4.9.0"},"reference-count":66,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T00:00:00Z","timestamp":1704931200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Nuclear Research Institute","award":["CB-302"],"award-info":[{"award-number":["CB-302"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>(1) Background: This study aims to evaluate the efficacy and safety of non-thermal plasma (NTP) therapy in accelerating wound healing in patients who have undergone laparoscopic and open surgeries. (2) Methods: NTP was applied using a needle-type reactor with an irradiance of 0.5 W\/cm2 on the surgical wounds of fifty patients after obtaining informed consent. Three NTP treatments, each lasting three minutes, were administered hourly. (3) Results: The pilot study showed that NTP-treated surgical wounds healed completely without any signs of infection, dehiscence, pain, or itching. Notably, patients reported minimal pain after the NTP treatment. Visual assessments conducted twenty-four hours after surgery revealed no redness or fluid discharge. Comparisons with traditionally sutured wounds indicated that NTP-treated wounds healed at a rate equivalent to seven days. (4) Conclusions: The application of NTP in laparoscopic and open wounds proved safe and effective, expediting the wound healing process and eliminating clinical risks post-surgery. Significantly, NTP facilitated a healing rate within twenty-four hours, equivalent to seven days for suture-treated wounds, significantly reducing the hospitalization time to a single day. These findings highlight the potential of NTP to be a transformative approach for promoting postoperative recovery.<\/jats:p>","DOI":"10.3390\/jcm13020408","type":"journal-article","created":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T08:27:07Z","timestamp":1704961627000},"page":"408","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Harnessing Non-Thermal Plasma to Supercharge Recovery in Abdominal Surgeries: A Pilot Study"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0495-9118","authenticated-orcid":false,"given":"Benjam\u00edn G.","family":"Rodr\u00edguez-M\u00e9ndez","sequence":"first","affiliation":[{"name":"Plasma Physics Laboratory, Instituto Nacional de Investigaciones Nucleares, Carretera M\u00e9xico-Toluca S\/N, La Marquesa, Ocoyoacac 52750, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3645-4373","authenticated-orcid":false,"given":"R\u00e9gulo","family":"L\u00f3pez-Callejas","sequence":"additional","affiliation":[{"name":"Plasma Physics Laboratory, Instituto Nacional de Investigaciones Nucleares, Carretera M\u00e9xico-Toluca S\/N, La Marquesa, Ocoyoacac 52750, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7450-0014","authenticated-orcid":false,"given":"Antonio","family":"Mercado-Cabrera","sequence":"additional","affiliation":[{"name":"Plasma Physics Laboratory, Instituto Nacional de Investigaciones Nucleares, Carretera M\u00e9xico-Toluca S\/N, La Marquesa, Ocoyoacac 52750, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3965-8312","authenticated-orcid":false,"given":"Rosendo","family":"Pe\u00f1a-Eguiluz","sequence":"additional","affiliation":[{"name":"Plasma Physics Laboratory, Instituto Nacional de Investigaciones Nucleares, Carretera M\u00e9xico-Toluca S\/N, La Marquesa, Ocoyoacac 52750, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ra\u00fal","family":"Valencia-Alvarado","sequence":"additional","affiliation":[{"name":"Plasma Physics Laboratory, Instituto Nacional de Investigaciones Nucleares, Carretera M\u00e9xico-Toluca S\/N, La Marquesa, Ocoyoacac 52750, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Betancourt-\u00c1ngeles","sequence":"additional","affiliation":[{"name":"Medical Center ISSEMyM Toluca, Av. 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