{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T11:19:20Z","timestamp":1784114360641,"version":"3.55.0"},"reference-count":38,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2024,1,12]],"date-time":"2024-01-12T00:00:00Z","timestamp":1705017600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Oral lichen planus (OLP) is a chronic inflammatory disease of autoimmune origin that affects the skin and mucous membranes. The aim of this study was to assess the effectiveness of infrared thermography (IRT) as a diagnostic tool in patients with oral lichen planus (OLP), as well as disturbances in taste perception, in cases with and without tongue involvement. A case-control study was carried out in a sample of 87 patients divided into three groups: healthy individuals (controls; n = 43), OLP patients without involvement of the tongue (n = 24), and OLP patients with involvement of the tongue (n = 20). The patient symptoms and the clinical characteristics of the lesions were assessed. Four thermal images of the tongue were obtained using IRT: dorsum, right and left lateral surface, and tip of the tongue. General taste perception capacity and subjective sweet, acid, salty, and bitter sensation were evaluated in all three groups. There were no statistically significant differences in the IRT values among the three groups (p \u2265 0.05). In the OLP patients with involvement of the tongue, significantly higher values were observed in the mixed forms of the disease (p = 0.032). The OLP patients with and without involvement of the tongue showed no significant alterations in taste sensation (p = 0.69). IRT may serve as a complementary tool for assessing the activity of OLP with involvement of the tongue. However, more research is needed in this field.<\/jats:p>","DOI":"10.3390\/jcm13020435","type":"journal-article","created":{"date-parts":[[2024,1,12]],"date-time":"2024-01-12T09:24:11Z","timestamp":1705051451000},"page":"435","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Diagnostic Infrared Thermography of the Tongue and Taste Perception in Patients with Oral Lichen Planus: Case-Control Study"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0081-5210","authenticated-orcid":false,"given":"Elena","family":"Nicolas-Rodriguez","sequence":"first","affiliation":[{"name":"Faculty of Medicine and Odontology, Hospital Morales Meseguer, Cl\u00ednica Odontol\u00f3gica, Marqu\u00e9s del Los V\u00e9lez s\/n, 30008 Murcia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Pons-Fuster","sequence":"additional","affiliation":[{"name":"Departamento de Anatom\u00eda Humana y Psicobiolog\u00eda, Faculty of Medicine and Odontology, Biomedical Research Institute (IMIB-Arrixaca), University of Murcia Spain, 30100 Murcia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3314-8613","authenticated-orcid":false,"given":"Pia","family":"L\u00f3pez-Jornet","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Odontology, Hospital Morales Meseguer, Cl\u00ednica Odontol\u00f3gica, Marqu\u00e9s del Los V\u00e9lez s\/n, 30008 Murcia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,1,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1111\/odi.13704","article-title":"Oral potentially malignant disorders: A consensus report from an international seminar on nomenclature and classification, convened by the WHO Collaborating Centre for Oral Cancer","volume":"27","author":"Warnakulasuriya","year":"2021","journal-title":"Oral Dis."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"104550","DOI":"10.1016\/j.oraloncology.2019.104550","article-title":"Oral potentially malignant disorders: A comprehensive review on clinical aspects and management","volume":"102","author":"Warnakulasuriya","year":"2020","journal-title":"Oral Oncol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1111\/odi.13323","article-title":"Worldwide prevalence of oral lichen planus: A systematic review and meta-analysis","volume":"27","author":"Warnakulasuriya","year":"2021","journal-title":"Oral Dis."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1111\/prd.12260","article-title":"Oral lichen planus: A disease or a spectrum of tissue reactions? Types, causes, diagnostic algorhythms, prognosis, management strategies","volume":"80","author":"Carrozzo","year":"2019","journal-title":"Periodontology 2000"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1007\/s00403-016-1667-2","article-title":"Oral lichen planus: A literature review and update","volume":"308","author":"Alrashdan","year":"2016","journal-title":"Arch. Dermatol. Res."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1111\/j.1600-0714.2010.00894.x","article-title":"A retrospective clinicopathological study of 550 patients with oral lichen planus in south-eastern Spain","volume":"39","year":"2010","journal-title":"J. Oral Pathol. Med."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1002\/hed.26006","article-title":"Potentially malignant disorders of the oral cavity and oral dysplasia: A systematic review and meta-analysis of malignant transformation rate by subtype","volume":"42","author":"Iocca","year":"2020","journal-title":"Head Neck"},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Louisy, A., Humbert, E., and Samimi, M. (2023). Oral Lichen Planus: An Update on Diagnosis and Management. Am. J. Clin. Dermatol., in press.","DOI":"10.1007\/s40257-023-00814-3"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/s00784-019-02951-8","article-title":"Oral health-related quality of life in different clinical forms of oral lichen planus","volume":"24","author":"Parlatescu","year":"2020","journal-title":"Clin. Oral Investig."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1053\/joms.2000.16629","article-title":"Oral lichen planus: A benign lesion","volume":"58","author":"Eisenberg","year":"2000","journal-title":"J. Oral Maxillofac. Surg."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1034\/j.1600-0714.2003.00125.x","article-title":"Lack of clinicopathologic correlation in the diagnosis of oral lichen planus based on the presently available diagnostic criteria and suggestions for modifications","volume":"32","year":"2003","journal-title":"J. Oral Pathol. Med."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/j.1529-8019.2010.01322.x","article-title":"Lichen planus and lichenoid reactions of the oral mucosa","volume":"23","author":"Schlosser","year":"2010","journal-title":"Dermatol. Ther."},{"key":"ref_13","first-page":"494","article-title":"Oral lichen planus: Clinical presentation and management","volume":"68","author":"Edwards","year":"2002","journal-title":"J. Can. Dent. Assoc."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1111\/odi.12885","article-title":"Rate of malignant transformation of oral lichen planus: A systematic review","volume":"25","author":"Giuliani","year":"2019","journal-title":"Oral Dis."},{"key":"ref_15","first-page":"105","article-title":"The use of infrared thermography in the evaluation of oral lesions","volume":"9","author":"White","year":"1987","journal-title":"Int. J. Tissue React."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.infrared.2012.03.007","article-title":"Medical applications of infrared thermography: A review","volume":"55","author":"Lahiri","year":"2012","journal-title":"Infrared Phys. Technol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"e059833","DOI":"10.1136\/bmjopen-2021-059833","article-title":"Use of infrared thermography in medical diagnostics: A scoping review protocol","volume":"12","author":"Brucher","year":"2022","journal-title":"BMJ Open"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"12305","DOI":"10.3390\/s140712305","article-title":"Infrared thermography for temperature measurement and non-destructive testing","volume":"14","author":"Usamentiaga","year":"2014","journal-title":"Sensors"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1111\/jocd.14748","article-title":"Evaluation of skin using infrared thermal imaging for dermatology and aesthetic applications","volume":"21","author":"Vergilio","year":"2022","journal-title":"J. Cosmet. Dermatol."},{"key":"ref_20","unstructured":"Zhihao, J., Kai, Z., Xiaozuo, L., and Li, X. (2008, January 12\u201314). Analysis of tongue information in coronary artery disease. Proceedings of the 2008 IEEE International Symposium on IT in Medicine and Education, Xiamen, China."},{"key":"ref_21","first-page":"e65140","article-title":"Objectification of Tongue Diagnosis in Traditional Medicine, Data Analysis, and Study Application","volume":"194","author":"Feng","year":"2023","journal-title":"J. Vis. Exp."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"6841460","DOI":"10.1155\/2018\/6841460","article-title":"Relationship between Tongue Temperature Estimated by Infrared Thermography, Tongue Color, and Cold-Heat Pathological Patterns: A Retrospective Chart Review Study","volume":"27","author":"Baek","year":"2018","journal-title":"Evid.-Based Complement. Altern. Med."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"3186208","DOI":"10.1155\/2020\/3186208","article-title":"Human Tongue Thermography Could Be a Prognostic Tool for Prescreening the Type II Diabetes Mellitus","volume":"14","author":"Thirunavukkarasu","year":"2020","journal-title":"Evid.-Based Complement. Altern. Med."},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Nicolas-Rodriguez, E., Garcia-Martinez, A., Molino-Pagan, D., Marin-Martinez, L., Pons-Fuster, E., and L\u00f3pez-Jornet, P. (2022). Thermography as a Non-Ionizing Quantitative Tool for Diagnosing Burning Mouth Syndrome: Case-Control Study. Int. J. Environ. Res. Public Health, 19.","DOI":"10.3390\/ijerph19158903"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.imr.2012.09.001","article-title":"Review on the current trends in tongue diagnosis systems","volume":"1","author":"Jung","year":"2012","journal-title":"Integr. Med. Res."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.infrared.2017.12.011","article-title":"Relationship between dynamic infrared thermal images and blood perfusion rate of the tongue in anaemia patients","volume":"89","author":"Xie","year":"2018","journal-title":"Infrared Phys. Technol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.foodres.2018.08.066","article-title":"A non-invasive measurement of tongue surface temperature","volume":"116","author":"Lv","year":"2022","journal-title":"Food Res. Int."},{"key":"ref_28","first-page":"287","article-title":"Impaired Taste Perception in Li-chen Planus Patients with Tongue Involvement","volume":"19","author":"Suter","year":"2021","journal-title":"Oral Health Prev. Dent."},{"key":"ref_29","first-page":"92","article-title":"Magnitud del efecto para pruebas de normalidad en investigaci\u00f3n en salud","volume":"7","year":"2018","journal-title":"Investig. Educ. Med."},{"key":"ref_30","first-page":"45","article-title":"Clinical evaluation of thermography as a diagnostic tool in oral and maxillo-facial lesions","volume":"25","author":"Gzawi","year":"2018","journal-title":"J. R. Med. Serv."},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Aboushady, M.A., Talaat, W., Hamdoon, Z., Elshazly, M.T., Ragy, N., Bourauel, C., and Talaat, S. (2021). Thermography as a non-ionizing quantitative tool for diagnosing periapical inflammatory lesions. BMC Oral Health, 21.","DOI":"10.1186\/s12903-021-01618-9"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1111\/joor.13374","article-title":"Thermography in complementary assessments of head and neck muscles: A scoping review","volume":"49","author":"Balata","year":"2022","journal-title":"J. Oral Rehabil."},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Wzi\u0105tek-Kuczmik, D., Niedzielska, I., Mrowiec, A., Ba\u0142amut, K., Handzel, M., and Szurko, A. (2022). Is Thermal Imaging a Helpful Tool in Diagnosis of Asymptomatic Odontogenic Infection Foci-A Pilot Study. Int. J. Environ. Res. Public Health, 19.","DOI":"10.3390\/ijerph192316325"},{"key":"ref_34","first-page":"e388-92","article-title":"Morphometric analysis of the dorsum linguae in patients with Oral Lichen Planus","volume":"14","year":"2009","journal-title":"Med. Oral Patol. Oral Cirug\u00eda Bucal"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1007\/s00784-016-1860-x","article-title":"Gustatory function and taste perception in patients with oral lichen planus and tongue involvement","volume":"21","author":"Suter","year":"2017","journal-title":"Clin. Oral Investig."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/jtxs.12573","article-title":"Relationship between polypharmacy, xerostomia, gustatory sensitivity, and swallowing complaints in the elderly: A multidisciplinary approach","volume":"52","author":"Fernandes","year":"2021","journal-title":"J. Texture Stud."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1054\/bjom.2000.0335","article-title":"Oral lichen planus: A review","volume":"38","author":"Mollaoglu","year":"2000","journal-title":"Br. J. Oral Maxillofac. Surg."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1016\/j.oooo.2023.01.014","article-title":"World Workshop on Oral Medicine VIII: Development of a core outcome set for oral lichen planus: A systematic review of outcome domains","volume":"135","author":"Ramesh","year":"2023","journal-title":"Oral Surg. Oral Med. Oral Pathol. Oral Radiol."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/2\/435\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T13:45:43Z","timestamp":1760103943000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/2\/435"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,12]]},"references-count":38,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2024,1]]}},"alternative-id":["jcm13020435"],"URL":"https:\/\/doi.org\/10.3390\/jcm13020435","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,12]]}}}