{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T18:24:00Z","timestamp":1793125440124,"version":"4.5.0"},"reference-count":127,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2024,1,19]],"date-time":"2024-01-19T00:00:00Z","timestamp":1705622400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>The most prevalent zoonotic disease is brucellosis, which poses a significant threat for worldwide public health. Particularly in endemic areas, spinal involvement is a major source of morbidity and mortality and can complicate the course of the disease. The diagnosis of Brucella spondylitis is challenging and should be suspected in the appropriate epidemiological and clinical context, in correlation with microbiological and radiological findings. Treatment depends largely on the affected parts of the body. Available treatment options include antibiotic administration for an adequate period of time and, when appropriate, surgical intervention. In this article, we examined the most recent data on the pathophysiology, clinical manifestation, diagnosis, and management of spinal brucellosis in adults.<\/jats:p>","DOI":"10.3390\/jcm13020595","type":"journal-article","created":{"date-parts":[[2024,1,19]],"date-time":"2024-01-19T11:04:57Z","timestamp":1705662297000},"page":"595","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":77,"title":["Brucella Spondylitis: Current Knowledge and Recent Advances"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6981-8535","authenticated-orcid":false,"given":"Nikolaos","family":"Spernovasilis","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, German Oncology Center, 4108 Limassol, Cyprus"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Apostolos","family":"Karantanas","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging, University Hospital of Heraklion, 71500 Heraklion, Greece"},{"name":"Advanced Hybrid Imaging Systems, Institute of Computer Science, FORTH, 71500 Heraklion, Greece"},{"name":"Department of Radiology, School of Medicine, University of Crete, 71003 Heraklion, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioulia","family":"Markaki","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Thoracic Diseases General Hospital Sotiria, 11527 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afroditi","family":"Konsoula","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, General Hospital of Sitia, 72300 Sitia, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zisis","family":"Ntontis","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Trauma Surgery, Venizeleio General Hospital of Heraklion, 71409 Heraklion, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christos","family":"Koutserimpas","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology, \u201c251\u201d Hellenic Air Force General Hospital of Athens, 11525 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kalliopi","family":"Alpantaki","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Trauma Surgery, Venizeleio General Hospital of Heraklion, 71409 Heraklion, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,1,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.nic.2015.01.004","article-title":"Spinal brucellosis","volume":"25","author":"Tali","year":"2015","journal-title":"Neuroimaging Clin. 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