{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T22:37:13Z","timestamp":1790980633801,"version":"4.1.0"},"reference-count":38,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T00:00:00Z","timestamp":1707177600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: The aim of this clinical study was to compare the occlusal caries detection (OCD) performance of the intraoral scanners (IOSs) Trios 4 (TIO, 3Shape) and Emerald S (EME, Planmeca) and the Diagnocam (DIA, KaVo) with the established visual (WHO) examination (VIS, reference method). Methods: Between 08\/2022 and 02\/2023, 60 children (mean age 9.6 \u00b1 2.5 years) were examined as part of their regular dental checkups. OCD was performed at the tooth level, separately for primary and permanent unrestored teeth. Furthermore, two thresholds were analyzed: sound versus overall caries (pooled data of enamel and dentin caries, TH1) and pooled data of sound and enamel caries versus dentin caries (TH2). Results: The best agreement with the reference method (reliability) in both dentitions was obtained for DIA (\u0138 = 0.829\/\u0138 = 0.846; primary\/permanent teeth), followed by EME (\u0138 = 0.827\/\u0138 = 0.837) and TIO (\u0138 = 0.714\/\u0138 = 0.680). Similar results were shown for the diagnostic quality (sensitivity, specificity and area under the curve of the receiver operating characteristic curve), with higher values for TH1 than for TH2. Both IOSs and the DIA showed worse results than the reference method VIS. Conclusions: Currently, IOS should be used as an additional caries detection tool, especially for visualization, and cannot be recommended as a basic tool for diagnosis or invasive\/noninvasive therapy decisions in OCD.<\/jats:p>","DOI":"10.3390\/jcm13040925","type":"journal-article","created":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T12:38:24Z","timestamp":1707223104000},"page":"925","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Occlusal Caries Detection with Intraoral Scanners in Pediatric Dentistry: A Comparative Clinical Study"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4562-8232","authenticated-orcid":false,"given":"Nelly","family":"Schulz-Weidner","sequence":"first","affiliation":[{"name":"Department of Pediatric Dentistry, Dental Clinic, Justus Liebig University, Schlangenzahl 14, 35392 Giessen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Gruber","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, Dental Clinic, Justus Liebig University, Schlangenzahl 14, 35392 Giessen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernd","family":"W\u00f6stmann","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, Dental Clinic, Justus Liebig University, Schlangenzahl 14, 35392 Giessen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constanze Friederike","family":"Uebereck","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry, Dental Clinic, Justus Liebig University, Schlangenzahl 14, 35392 Giessen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norbert","family":"Kr\u00e4mer","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry, Dental Clinic, Justus Liebig University, Schlangenzahl 14, 35392 Giessen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4747-824X","authenticated-orcid":false,"given":"Maximiliane Amelie","family":"Schlenz","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, Dental Clinic, Justus Liebig University, Schlangenzahl 14, 35392 Giessen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,2,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Tabatabaian, F., Namdari, M., Mahshid, M., Vora, S.R., and Mirabbasi, S. (2022). Accuracy and precision of intraoral scanners for shade matching: A systematic review. J. Prosthet. Dent.","DOI":"10.1016\/j.prosdent.2022.08.034"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Jung, K., Giese-Kraft, K., Fischer, M., Schulze, K., Schlueter, N., and Ganss, C. (2022). Visualization of dental plaque with a 3D-intraoral-scanner-A tool for whole mouth planimetry. PLoS ONE, 17.","DOI":"10.1371\/journal.pone.0276686"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"262","DOI":"10.4041\/kjod.2018.48.4.262","article-title":"Clinical application of an intraoral scanner for serial evaluation of orthodontic tooth movement: A preliminary study","volume":"48","author":"Yun","year":"2018","journal-title":"Korean J. Orthod."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Angelone, F., Ponsiglione, A.M., Ricciardi, C., Cesarelli, G., Sansone, M., and Amato, F. (2023). Diagnostic Applications of Intraoral Scanners: A Systematic Review. J. Imaging, 9.","DOI":"10.3390\/jimaging9070134"},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Schlenz, M.A., Schupp, B., Schmidt, A., W\u00f6stmann, B., Baresel, I., Kr\u00e4mer, N., and Schulz-Weidner, N. (2022). New Caries Diagnostic Tools in Intraoral Scanners: A Comparative In Vitro Study to Established Methods in Permanent and Primary Teeth. Sensors, 22.","DOI":"10.3390\/s22062156"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1111\/j.1600-0528.1999.tb02029.x","article-title":"Underestimation of the prevalence of approximal caries and inadequate restorations in a clinical epidemiological study","volume":"27","author":"Poorterman","year":"1999","journal-title":"Community Dent. Oral Epidemiol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1159\/000016584","article-title":"Value of bite-wing radiographs in a clinical epidemiological study and their effect on the DMFS index","volume":"34","author":"Poorterman","year":"2000","journal-title":"Caries Res."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1007\/s00784-018-2512-0","article-title":"Evaluation of occlusal caries detection and assessment by visual inspection, digital bitewing radiography and near-infrared light transillumination","volume":"22","author":"Schaefer","year":"2018","journal-title":"Clin. Oral Investig."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"3691","DOI":"10.1007\/s00784-019-03058-w","article-title":"When to intervene in the caries process? An expert Delphi consensus statement","volume":"23","author":"Schwendicke","year":"2019","journal-title":"Clin. Oral Investig."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s40368-015-0218-4","article-title":"Best clinical practice guidance for management of early caries lesions in children and young adults: An EAPD policy document","volume":"17","author":"Ekstrand","year":"2016","journal-title":"Eur. Arch. Paediatr. Dent."},{"key":"ref_11","unstructured":"Atena, G., Daniela, J., and Aurora Doris, F. (2022). Dental Caries, IntechOpen."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s00784-010-0390-1","article-title":"Diagnostic performance of the universal visual scoring system (UniViSS) on occlusal surfaces","volume":"15","author":"Henschel","year":"2011","journal-title":"Clin. Oral Investig."},{"key":"ref_13","first-page":"531","article-title":"Caries detection and diagnostics with near-infrared light transillumination: Clinical experiences","volume":"45","author":"Hickel","year":"2014","journal-title":"Quintessence Int."},{"key":"ref_14","first-page":"105","article-title":"In Vitro Evaluation of Occlusal Caries Detection Methods in Primary and Permanent Teeth: A Comparison of CarieScan PRO, DIAGNOdent Pen, and DIAGNOcam Methods","volume":"38","author":"Kara","year":"2020","journal-title":"Photobiomodul. Photomed. Laser Surg."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"4801","DOI":"10.1007\/s00784-021-04024-1","article-title":"Systematic review and meta-analysis of diagnostic methods for occlusal surface caries","volume":"25","author":"Kapor","year":"2021","journal-title":"Clin. Oral Investig."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1159\/000528731","article-title":"Fluorescence Spectroscopy Shows Porphyrins Produced by Cultured Oral Bacteria Differ Depending on Composition of Growth Media","volume":"57","author":"Lennon","year":"2023","journal-title":"Caries Res."},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Braga, M.M., de Benedetto, M.S., Imparato, J.C., and Mendes, F.M. (2010). New methodology to assess activity status of occlusal caries in primary teeth using laser fluorescence device. J. Biomed. Opt., 15.","DOI":"10.1117\/1.3463007"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1159\/000328673","article-title":"Clinical performance of two fluorescence-based methods in detecting occlusal caries lesions in primary teeth","volume":"45","author":"Matos","year":"2011","journal-title":"Caries Res."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1159\/000501257","article-title":"Occlusal Caries Detection and Diagnosis Using Visual ICDAS Criteria, Laser Fluorescence Measurements, and Near-Infrared Light Transillumination Images","volume":"29","author":"Tassoker","year":"2019","journal-title":"Med. Princ. Pract."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1034\/j.1600-0722.2001.109001014.x","article-title":"Clinical performance of a laser fluorescence device for detection of occlusal caries lesions","volume":"109","author":"Lussi","year":"2001","journal-title":"Eur. J. Oral Sci."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1007\/s40368-021-00675-6","article-title":"Minimal intervention dentistry for managing carious lesions into dentine in primary teeth: An umbrella review","volume":"23","author":"BaniHani","year":"2022","journal-title":"Eur. Arch. Paediatr. Dent."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"103861","DOI":"10.1016\/j.jdent.2021.103861","article-title":"Reflected near-infrared light versus bite-wing radiography for the detection of proximal caries: A multicenter prospective clinical study conducted in private practices","volume":"116","author":"Metzger","year":"2022","journal-title":"J. Dent."},{"key":"ref_23","unstructured":"Pieper, K., and Blumenstein, A. (1993). Die Zahnmedizinische Untersuchung Im Rahmen Der Gruppenprophylaxe: Ein Leitfaden F\u00fcr Die Edv-Gest\u00fctzte Erfolgskontrolle, Druckhaus Marburg."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"159","DOI":"10.2307\/2529310","article-title":"The measurement of observer agreement for categorical data","volume":"33","author":"Landis","year":"1977","journal-title":"Biometrics"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"315","DOI":"10.2334\/josnusd.16-0595","article-title":"Alternative methods to visual and radiographic examinations for approximal caries detection","volume":"59","author":"Abogazalah","year":"2017","journal-title":"J. Oral. Sci."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"13240","DOI":"10.1038\/s41598-022-17576-3","article-title":"Author Correction: Automated caries detection in vivo using a 3D intraoral scanner","volume":"12","author":"Michou","year":"2022","journal-title":"Sci. Rep."},{"key":"ref_27","unstructured":"Walsh, L. (2018). Dental Caries, IntechOpen."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"270729","DOI":"10.1155\/2010\/270729","article-title":"Caries Detection Methods Based on Changes in Optical Properties between Healthy and Carious Tissue","volume":"2010","author":"Karlsson","year":"2010","journal-title":"Int. J. Dent."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"17012","DOI":"10.1038\/bdjopen.2017.12","article-title":"Clinical performance of the near-infrared imaging system VistaCam iX Proxi for detection of approximal enamel lesions","volume":"3","author":"Jablonski","year":"2017","journal-title":"BDJ Open"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1348\/000711006X126600","article-title":"Computing inter-rater reliability and its variance in the presence of high agreement","volume":"61","author":"Gwet","year":"2008","journal-title":"Br. J. Math. Stat. Psychol."},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Hosmer, D.W., and Lemeshow, S. (2000). Applied Logistic Regression, Wiley.","DOI":"10.1002\/0471722146"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"339","DOI":"10.14219\/jada.archive.2012.0176","article-title":"The performance of conventional and fluorescence-based methods for occlusal caries detection: An in vivo study with histologic validation","volume":"143","author":"Diniz","year":"2012","journal-title":"J. Am. Dent. Assoc."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1111\/jopr.13770","article-title":"Performance of the caries diagnosis feature of intraoral scanners and near-infrared imaging technology-A narrative review","volume":"32","author":"Lin","year":"2023","journal-title":"J. Prosthodont."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/j.cden.2005.05.009","article-title":"Quantitative light fluorescence: A technology for early monitoring of the caries process","volume":"49","author":"Stookey","year":"2005","journal-title":"Dent. Clin. N. Am."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/jphd.12105","article-title":"Variables affecting the inter- and intra-examiner reliability of ICDAS for occlusal caries diagnosis in permanent molars","volume":"76","author":"Qudeimat","year":"2016","journal-title":"J. Public Health Dent."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1111\/j.1600-0528.2008.00436.x","article-title":"Occlusal caries detection in permanent molars according to WHO basic methods, ICDAS II and laser fluorescence measurements","volume":"36","author":"Berger","year":"2008","journal-title":"Community Dent. Oral Epidemiol."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"1960","DOI":"10.1377\/hlthaff.2018.05102","article-title":"Advancement Of Teledentistry At The University Of Rochester\u2019s Eastman Institute For Oral Health","volume":"37","author":"McLaren","year":"2018","journal-title":"Health Aff."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"38","DOI":"10.9734\/cjast\/2021\/v40i3531572","article-title":"Clinical Trial of the Canary System for Proximal Caries Detection: A Comparative Study","volume":"40","author":"Jan","year":"2021","journal-title":"CJAST"}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/4\/925\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T13:55:37Z","timestamp":1760104537000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/4\/925"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,6]]},"references-count":38,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2024,2]]}},"alternative-id":["jcm13040925"],"URL":"https:\/\/doi.org\/10.3390\/jcm13040925","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,6]]}}}