{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:44:24Z","timestamp":1760143464744,"version":"build-2065373602"},"reference-count":8,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T00:00:00Z","timestamp":1707264000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Late ischaemic consequences of type A aortic dissection are rare. We present a 6-year late complication of type A aortic dissection treated by Bentall surgery in a 41-year-old patient. The patient presented with several episodes of lipothymia associated with hypertensive attacks with anisotension, cervicalgia, hemicranial headache, abdominal pain and lower limb slipping initially on exertion and later at rest. On dynamic examination, we diagnosed an intermittent dynamic occlusion of the aortic arch and rare LOX gene variation, which is considered to be associated with aneurysm or dissection of the ascending aorta in young patients. Surgical treatment by replacement of the ascending aorta and the aortic arch with reimplantation of the brachiocephalic trunk (BcTr) allowed the symptoms to resolve.<\/jats:p>","DOI":"10.3390\/jcm13040952","type":"journal-article","created":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T06:12:58Z","timestamp":1707286378000},"page":"952","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Late Post-Dissection Dynamic Intermittent Malperfusion of the Aortic Arch in Association with a Rare Heterogenous LOX Gene Variation"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-2621-7204","authenticated-orcid":false,"given":"Barbara","family":"Leclercq","sequence":"first","affiliation":[{"name":"Vascular Medicine and Arterial Hypertension Departement, La Timone Hospital, CHU Timone, 264, rue Saint-Pierre, 13385 Marseille cedex 5, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julien","family":"Bertolino","sequence":"additional","affiliation":[{"name":"Vascular Medicine and Arterial Hypertension Departement, La Timone Hospital, CHU Timone, 264, rue Saint-Pierre, 13385 Marseille cedex 5, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandre","family":"Rossillon","sequence":"additional","affiliation":[{"name":"Vascular Surgery Department, La Timone Hospital, CHU Timone, 264, rue Saint-Pierre, 13385 Marseille cedex 5, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vlad","family":"Gariboldi","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, La Timone Hospital, CHU Timone, 264, rue Saint-Pierre, 13385 Marseille cedex 5, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"El Harake","sequence":"additional","affiliation":[{"name":"Vascular Medicine and Arterial Hypertension Departement, La Timone Hospital, CHU Timone, 264, rue Saint-Pierre, 13385 Marseille cedex 5, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7ois","family":"Silhol","sequence":"additional","affiliation":[{"name":"Vascular Medicine and Arterial Hypertension Departement, La Timone Hospital, CHU Timone, 264, rue Saint-Pierre, 13385 Marseille cedex 5, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michel","family":"Bartoli","sequence":"additional","affiliation":[{"name":"Vascular Surgery Department, La Timone Hospital, CHU Timone, 264, rue Saint-Pierre, 13385 Marseille cedex 5, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernard","family":"Vaisse","sequence":"additional","affiliation":[{"name":"Vascular Medicine and Arterial Hypertension Departement, La Timone Hospital, CHU Timone, 264, rue Saint-Pierre, 13385 Marseille cedex 5, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Axel","family":"Bartoli","sequence":"additional","affiliation":[{"name":"Radiology Department, La Timone Hospital, CHU Timone, 264, rue Saint-Pierre, 13385 Marseille cedex 5, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1277-150X","authenticated-orcid":false,"given":"Gabrielle","family":"Sarlon-Bartoli","sequence":"additional","affiliation":[{"name":"Vascular Medicine and Arterial Hypertension Departement, La Timone Hospital, CHU Timone, 264, rue Saint-Pierre, 13385 Marseille cedex 5, France"},{"name":"Center for CardioVascular and Nutrition Research (C2VN), Aix Marseille University, 13005 Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,2,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1053\/j.semvascsurg.2021.02.003","article-title":"Epidemiology of aortic dissection","volume":"34","author":"Sen","year":"2021","journal-title":"Semin. 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