{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T22:15:35Z","timestamp":1768342535240,"version":"3.49.0"},"reference-count":47,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2024,2,8]],"date-time":"2024-02-08T00:00:00Z","timestamp":1707350400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Ankle arthroscopy is indicated for both diagnosis and treatment of a large spectrum of common ankle disorders. It has certain advantages over the open procedure; however, it is important to recognize that there are some complications associated with it. Infections after this procedure are quite uncommon, with an overall estimated incidence of 2%. Given the low incidence of infections after ankle arthroscopy, not a great deal of literature on the topic has been published. The present review aims to provide an overview of the incidence, diagnosis, and treatment of infections after ankle arthroscopy. Methods: A systematic review of the literature indexed in the PubMed, MEDLINE, and Cochrane Library databases using search term \u201cankle arthroscopy infections\u201d was performed in November 2023. No restrictions were applied concerning the date of publication. The Preferred reporting items for systematic reviews and meta-analyses (PRISMA) were followed. Among all surgical operations for the treatment of ankle and foot pathologies, we included articles with a described superficial or deep infection after ankle arthroscopy. Results: The search resulted in 201 studies. Only 21 studies met our inclusion criteria, and they were included in this systematic review. We evaluated 1706 patients who underwent 1720 arthroscopic tibiotalar procedures at an average age of 42 years old. Out of the 1720 procedures, 41 (2%) were complicated by infection. We divided infectious complications into superficial (68%; 28\/41) and deep (32%; 13\/41) infections. The most common pathogen isolated was Staphylococcus aureus. Arthroscopic arthrodesis was found to be the most affected by deep infections. Conclusions: Infection after ankle arthroscopy is an uncommon complication. Superficial infections were successfully treated with antibiotics, while surgical debridement, arthroscopic drainage, and intravenous antibiotics were necessary in cases of deep infections. Considering the amount of information on pathogens associated with knee and shoulder infections, there is still a lack of literature on pathogens associated with ankle infections, which makes their management difficulty.<\/jats:p>","DOI":"10.3390\/jcm13040983","type":"journal-article","created":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T09:04:01Z","timestamp":1707469441000},"page":"983","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Epidemiology and Treatment of Surgical Infection after Ankle Arthroscopy: A Systematic Review"],"prefix":"10.3390","volume":"13","author":[{"given":"Andrea","family":"De Fazio","sequence":"first","affiliation":[{"name":"Department of Orthopaedics and Traumatology, Fondazione Policlinico Universitario A. Gemelli IRCSS, 00168 Roma, Italy"},{"name":"Department of Orthopaedics and Traumatology, Universit\u00e0 Cattolica Del Sacro Cuore, 00168 Roma, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Beatrice","family":"Bocchi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology, Fondazione Policlinico Universitario A. Gemelli IRCSS, 00168 Roma, Italy"},{"name":"Department of Orthopaedics and Traumatology, Universit\u00e0 Cattolica Del Sacro Cuore, 00168 Roma, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guglielmo","family":"Miele","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology, Fondazione Policlinico Universitario A. Gemelli IRCSS, 00168 Roma, Italy"},{"name":"Department of Orthopaedics and Traumatology, Universit\u00e0 Cattolica Del Sacro Cuore, 00168 Roma, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pasquale","family":"Ruberto","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology, Fondazione Policlinico Universitario A. Gemelli IRCSS, 00168 Roma, Italy"},{"name":"Department of Orthopaedics and Traumatology, Universit\u00e0 Cattolica Del Sacro Cuore, 00168 Roma, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabrizio","family":"Forconi","sequence":"additional","affiliation":[{"name":"Clinic Villa Stuart, 00135 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Ziranu","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology, Fondazione Policlinico Universitario A. Gemelli IRCSS, 00168 Roma, Italy"},{"name":"Department of Orthopaedics and Traumatology, Universit\u00e0 Cattolica Del Sacro Cuore, 00168 Roma, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulio","family":"Maccauro","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology, Fondazione Policlinico Universitario A. Gemelli IRCSS, 00168 Roma, Italy"},{"name":"Department of Orthopaedics and Traumatology, Universit\u00e0 Cattolica Del Sacro Cuore, 00168 Roma, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2321-9665","authenticated-orcid":false,"given":"Raffaele","family":"Vitiello","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology, Fondazione Policlinico Universitario A. Gemelli IRCSS, 00168 Roma, Italy"},{"name":"Department of Orthopaedics and Traumatology, Universit\u00e0 Cattolica Del Sacro Cuore, 00168 Roma, Italy"},{"name":"Clinic Villa Stuart, 00135 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,2,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1097\/00003086-198207000-00003","article-title":"The classic. Arthroscope. Kenji Takagi. J. Jap. Orthop. Assoc., 1939","volume":"167","author":"Takagi","year":"1982","journal-title":"Clin. Orthop. Relat. Res."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1097\/00003086-200109000-00003","article-title":"Arthroscopy or the direct visualization of joints: An experimental cadaver study. 1931","volume":"390","author":"Burman","year":"2001","journal-title":"Clin. Orthop. Relat. Res."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1177\/036354658901700103","article-title":"Operative ankle arthroscopy. Long-term followup","volume":"17","author":"Martin","year":"1989","journal-title":"Am. J. Sports Med."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1177\/107110079801900315","article-title":"Arthroscopy of the Foot and Ankle: Current Concepts Review","volume":"19","author":"Chaytor","year":"1998","journal-title":"Foot Ankle Int."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.fcl.2013.02.001","article-title":"The role of ankle arthroscopy in acute ankle injuries of the athlete","volume":"18","author":"Hepple","year":"2013","journal-title":"Foot Ankle Clin."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/S0749-8063(96)90011-0","article-title":"Neurological complications of ankle arthroscopy","volume":"12","author":"Ferkel","year":"1996","journal-title":"Arthroscopy"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.fcl.2006.06.003","article-title":"Anterior and posterior ankle impingement","volume":"11","year":"2006","journal-title":"Foot Ankle Clin."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"2837","DOI":"10.1007\/s00167-014-2980-y","article-title":"Combined arthroscopic management of concurrent posterior and anterior ankle pathologies","volume":"22","author":"Abdelatif","year":"2014","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1097\/00003086-200110000-00010","article-title":"Complications in foot and ankle arthroscopy","volume":"391","author":"Ferkel","year":"2001","journal-title":"Clin. Orthop. Relat. Res."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1302\/0301-620X.105B3.BJJ-2022-0796.R1","article-title":"Complications following ankle arthroscopy","volume":"105-B","author":"Arshad","year":"2023","journal-title":"Bone Jt. J."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"963","DOI":"10.2106\/JBJS.I.00977","article-title":"Complications of ankle arthroscopy utilizing a contemporary noninvasive distraction technique","volume":"93","author":"Young","year":"2011","journal-title":"J. Bone Jt. Surg. Am."},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Complications in arthroscopy: The knee and other joints (1986). Committee on Complications of the Arthroscopy Association of North America. Arthroscopy, 2, 253\u2013258.","DOI":"10.1016\/S0749-8063(86)80080-9"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/S0749-8063(88)80030-6","article-title":"Complications in arthroscopic surgery performed by experienced arthroscopists","volume":"4","author":"Small","year":"1988","journal-title":"Arthroscopy"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1177\/107110079001000504","article-title":"Complications of ankle arthroscopy","volume":"10","author":"Barber","year":"1990","journal-title":"Foot Ankle."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1177\/107110070502600305","article-title":"Survey of tourniquet use in orthopaedic foot and ankle surgery","volume":"26","author":"Younger","year":"2005","journal-title":"Foot Ankle Int."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1097\/JSA.0b013e31828e5c6c","article-title":"Complications in ankle and foot arthroscopy","volume":"21","author":"Carlson","year":"2013","journal-title":"Sports Med. Arthrosc."},{"key":"ref_17","first-page":"279","article-title":"Infections in arthroscopy","volume":"23","author":"Sircana","year":"2019","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.arthro.2015.07.029","article-title":"Risk of Infection After Intra-articular Steroid Injection at the Time of Ankle Arthroscopy in a Medicare Population","volume":"32","author":"Werner","year":"2016","journal-title":"Arthroscopy"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1034\/j.1600-0838.2002.120202.x","article-title":"Arthroscopic treatment of impingement of the ankle reduces pain and enhances function","volume":"12","author":"Rasmussen","year":"2002","journal-title":"Scand. J. Med. Sci. Sports."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1053\/j.jfas.2011.11.011","article-title":"Complications associated with foot and ankle arthroscopy","volume":"51","author":"Deng","year":"2012","journal-title":"J. Foot Ankle Surg."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1016\/j.fas.2018.10.006","article-title":"Comparison of arthroscopic to open tibiotalocalcaneal arthrodesis in high-risk patients","volume":"25","author":"Baumbach","year":"2019","journal-title":"Foot Ankle Surg."},{"key":"ref_22","first-page":"387","article-title":"Complications after ankle and hindfoot arthroscopy","volume":"60","year":"2016","journal-title":"Rev. Esp. Cir. Ortop. Traumatol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1177\/036354659202000502","article-title":"Arthroscopic treatment of sports-related synovitis of the ankle","volume":"20","author":"Thein","year":"1992","journal-title":"Am. J. Sports Med."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"105906","DOI":"10.1016\/j.ijsu.2021.105906","article-title":"The PRISMA 2020 statement: An updated guideline for reporting systematic reviews","volume":"88","author":"Page","year":"2021","journal-title":"Int. J. Surg."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1034\/j.1600-0838.2000.010001002.x","article-title":"Studies of surgical outcome after patellar tendinopathy: Clinical significance of methodological deficiencies and guidelines for future studies. Victorian Institute of Sport Tendon Study Group","volume":"10","author":"Coleman","year":"2000","journal-title":"Scand. J. Med. Sci. Sports"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"2829","DOI":"10.1007\/s00402-021-04214-2","article-title":"Clinical outcomes of anterior tibiofibular ligament\u2019s distal fascicle transfer versus ligament reconstruction with InternalBrace\u2122 for chronic ankle instability patients","volume":"142","author":"Tian","year":"2022","journal-title":"Arch. Orthop. Trauma Surg."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"2309499019862502","DOI":"10.1177\/2309499019862502","article-title":"What should we be careful of ankle arthroscopy?","volume":"27","author":"Ahn","year":"2019","journal-title":"J. Orthop. Surg."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.fas.2017.01.004","article-title":"Arthroscopic versus open ankle arthrodesis","volume":"24","author":"Quayle","year":"2018","journal-title":"Foot Ankle Surg."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1186\/s13018-016-0490-y","article-title":"Arthroscopic arthrodesis for ankle arthritis without bone graft","volume":"11","author":"Duan","year":"2016","journal-title":"J. Orthop. Surg. Res."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1177\/1071100713481775","article-title":"Arthroscopic ankle arthrodesis in hemophilic arthropathy","volume":"34","author":"Bai","year":"2013","journal-title":"Foot Ankle Int."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.fas.2010.12.004","article-title":"Arthroscopic ankle arthrodesis: Are results reproducible irrespective of pre-operative deformity?","volume":"17","author":"Dannawi","year":"2011","journal-title":"Foot Ankle Surg."},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"Kim, E.S., Lee, K.T., Park, J.S., and Lee, Y.K. (2011). Arthroscopic anterior talofibular ligament repair for chronic ankle instability with a suture anchor technique. Orthopedics, 34.","DOI":"10.3928\/01477447-20110228-03"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.fas.2010.01.004","article-title":"Technique and results of arthroscopic treatment of posterior ankle impingement","volume":"17","author":"Galla","year":"2011","journal-title":"Foot Ankle Surg."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"695","DOI":"10.3113\/FAI.2007.0695","article-title":"Arthroscopic ankle arthrodesis","volume":"28","author":"Gougoulias","year":"2007","journal-title":"Foot Ankle Int."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1302\/0301-620X.87B3.15756","article-title":"Arthroscopic ankle arthrodesis","volume":"87","author":"Winson","year":"2005","journal-title":"J. Bone Jt. Surg. Br."},{"key":"ref_36","first-page":"144","article-title":"Arthrod\u00e8se tibio-talienne sous contr\u00f4le arthroscopique: Limites et indications [Arthroscopic tibio-talar arthrodesis: Limitations and indications in 20 patients]","volume":"89","author":"Pierre","year":"2003","journal-title":"Rev. Chir. Orthop. Reparatrice Appar. Mot."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0749-8063(00)90123-3","article-title":"Arthroscopic arthrodesis of the ankle joint","volume":"16","author":"Cameron","year":"2000","journal-title":"Arthroscopy"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1111\/j.1600-0838.1996.tb00100.x","article-title":"Ankle arthroscopy under local and general anaesthesia for diagnostic evaluation and treatment","volume":"6","author":"Rolf","year":"1996","journal-title":"Scand. J. Med. Sci. Sports."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1177\/107110079601700608","article-title":"Complications following arthroscopic ankle arthrodesis","volume":"17","author":"Crosby","year":"1996","journal-title":"Foot Ankle Int."},{"key":"ref_40","first-page":"437","article-title":"Anterior impingement of the ankle treated by arthroscopic removal of bony spurs","volume":"75","author":"Mahomed","year":"1993","journal-title":"J. Bone Joint Surg. Br."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1007\/BF00434550","article-title":"Arthroscopically assisted arthrodesis of the ankle joint","volume":"115","author":"Jerosch","year":"1996","journal-title":"Arch. Orthop. Trauma. Surg."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s00402-007-0389-5","article-title":"Posterior tibial nerve lesions in ankle arthroscopy","volume":"128","author":"Cugat","year":"2008","journal-title":"Arch. Orthop. Trauma. Surg."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"6695648","DOI":"10.1155\/2023\/6695648","article-title":"Stress-Induced Hyperglycemia is a Risk Factor for Surgical-Site Infections in Nondiabetic Patients with Open Leg Fractures","volume":"2023","author":"Cianni","year":"2023","journal-title":"Adv. Orthop."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1016\/j.injury.2021.10.020","article-title":"Are deep infections that present before and after 90 days from orthopaedic trauma different? An analysis of the validity of the recent change in CDC criteria for infections","volume":"53","author":"Wise","year":"2022","journal-title":"Injury"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1007\/s00167-016-4202-2","article-title":"Infections following arthroscopic rotator cuff repair: Incidence, risk factors, and prophylaxis","volume":"25","author":"Pauzenberger","year":"2017","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"3149","DOI":"10.1007\/s00167-021-06525-8","article-title":"Post-operative septic arthritis after arthroscopy: Modern diagnostic and therapeutic concepts","volume":"29","author":"Voss","year":"2021","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"S347","DOI":"10.1016\/j.otsr.2015.09.004","article-title":"Post-arthroscopy septic arthritis: Current data and practical recommendations","volume":"101","author":"Bauer","year":"2015","journal-title":"Orthop. Traumatol. Surg. Res."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/4\/983\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T13:57:06Z","timestamp":1760104626000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/4\/983"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,8]]},"references-count":47,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2024,2]]}},"alternative-id":["jcm13040983"],"URL":"https:\/\/doi.org\/10.3390\/jcm13040983","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,8]]}}}